Prosthetic Joint Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Impact of Three Probabilistic Antibiotic Therapy on Digestive Microbiota and Colonization With Multi-resistant Bacteria [NA]
This clinical trial investigates the impact of three probabilistic antibiotic regimens on the digestive microbiota and colonization with mul…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Antibiotic Prophylaxis in High-Risk Arthroplasty Patients [Phase 4]
Phase 4 Mayo Clinic clinical trial evaluating antibiotic prophylaxis in high-risk arthroplasty patients, currently enrolling by invitation. …
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Use of Biocompatible Thermoplastic Impregnated With Vancomycin as a Temporary Orthopedic Spacer [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a vancomycin-impregnated biocompatible thermoplastic spacer for temporary orthopedic use to address…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Bacteriophage Therapy for Morganella Morganii Prosthetic Joint Infection [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating bacteriophage therapy for prosthetic joint infection of the hip caused by …
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection [Phase 1, Phase 2]
A clinical trial update describes a bacteriophage therapy being evaluated for methicillin-susceptible Staphylococcus aureus prosthetic joint…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Rate of Total Joint Infection 90-day After Surgery Following Irrigation With Next Science No-Rinse Solution vs SOC Alone [NA]
This clinical trial update notes a recruiting study comparing irrigation with Next Science No-Rinse Solution versus standard of care for red…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Microbiota as Early Diagnostic and predictivE Factor for Osteoarthritic Degeneration and Microbial Contamination [NA]
This clinical trial explores whether the microbiota can serve as an early diagnostic and predictive marker for osteoarthritic degeneration a…
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: Short or Long Antibiotic Regimes in Orthopaedics [NA]
Completed clinical trial examining short versus long antibiotic regimens in orthopaedic infections, including osteomyelitis and prosthetic j…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With a Fracture [NA]
Clinical trial comparing single versus multiple prophylactic antibiotic doses to prevent prosthetic joint infection after primary total hip …
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol [Phase 4]
Phase 4 trial evaluating intraosseous vancomycin in primary total hip arthroplasty has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Efficacy and Tolerance of 4 Weeks of Tedizolid in Prosthetic Joint Infections Treated With Implant Removal [Phase 4]
A completed Phase 4 trial evaluating the efficacy and tolerability of a 4-week course of tedizolid in prosthetic joint infections treated wi…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Randomised Arthroplasty Infection Worldwide Multidomain Adaptive Platform (ROADMAP) Trial [Phase 4]
Phase 4 randomized adaptive platform trial ROADMAP evaluating management of prosthetic joint infections; currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With OA [NA]
A clinical trial evaluating whether a single versus multiple prophylactic antibiotic doses affects the risk of prosthetic-joint infection af…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Assessing the Performance of Shotgun Metagenomics in the Diagnosis of Complex Prosthetic Joint Infections
This study evaluates shotgun metagenomics as a diagnostic tool for complex prosthetic joint infections. The trial is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: PCA Loading Time Before Knee Prosthetic Joint Infection Revision [NA]
A clinical trial is evaluating PCA loading time prior to knee prosthetic joint infection revision surgery; recruitment has not started.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Is This PJI Really Acute: A Quantitative Sonication Fluid Analysis (Sonic)
A completed study evaluating a quantitative sonication fluid analysis for prosthetic joint infection.
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: A Second Trial of the Abbreviated Protocol Two-Stage Exchange [Phase 2]
This clinical trial update reports the completion of a Phase 2 trial evaluating an abbreviated protocol two-stage exchange for prosthetic jo…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty [Phase 4]
Phase 4 trial comparing SURGX Antimicrobial Gel to povidone-iodine skin incision prep in total shoulder arthroplasty has completed and resul…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections [Phase 1]
This update reports the completion of a Phase 1 study evaluating safety and activity of TRL1068 in prosthetic joint infections.
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: New Molecular Approaches for Diagnosis of Prosthetic Joint Infection
This clinical trial update describes new molecular approaches being explored to diagnose prosthetic joint infection. Enrollment is by invita…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Egyptian Arthroplasty Surgeons' Antibiotics Usage Awareness
A completed clinical trial from South Valley University assessed antibiotic usage awareness among Egyptian arthroplasty surgeons for prosthe…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-II) [NA]
A single-center study (PHOMIC-II) from the University of Zurich evaluated the effect of photodynamic therapy on the skin microbiome in the s…
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CLINICAL_TRIALS withdrawal · 2024-08-07Clinical Trial Update: Safety Study of High-dose Methylprednisolone in Fast-track Total Knee Arthroplasty
A safety study of high-dose methylprednisolone in fast-track total knee arthroplasty was withdrawn.
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: SHort Interval Full Two-stage Implant Exchange [NA]
A clinical trial titled 'SHort Interval Full Two-stage Implant Exchange' is currently recruiting at University Hospital, Montpellier to stud…
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Educatıon in Patıents Who Had Total Knee Prosthesıs [NA]
A clinical trial evaluating education for patients who have undergone total knee arthroplasty; the study is currently not yet recruiting.