Prosthetic Joint Infection
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Abbreviated Protocol for Two-Stage Exchange [Phase 2]
This clinical trial update reports Phase 2 results for an abbreviated two-stage exchange protocol in the treatment of prosthetic joint infec…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Expanded Access to Cyclic Irrigation in Patients Undergoing Exchange Arthroplasty
This clinical trial update notes that expanded access to the cyclic irrigation treatment for prosthetic joint infection in patients undergoi…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Methylene Blue in Total Knee Arthroplasty (TKA) [Phase 1]
Phase 1 clinical trial from University of Miami evaluating methylene blue in total knee arthroplasty, including potential use for prosthetic…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Can Intraosseous Antibiotics Improve the Results of Irrigation & Debridement and Prosthetic Retention for PJI? [Phase 4]
A Phase 4 study is investigating whether intraosseous antibiotics improve outcomes after irrigation and debridement with prosthetic retentio…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty [Phase 2, Phase 3]
Clinical trial update indicates PLG0206 is being evaluated in Phase 2/3 to prevent recurrent infection after DAIR in periprosthetic joint in…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Antibiotic-coated Braided Suture Study [NA]
A University of Miami-led clinical trial is evaluating an antibiotic-coated braided suture for preventing prosthetic joint infections, with …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Long Term Follow-up of Patients With Prosthetic Joint Infection of the Hip Treated at University Hospitals Leuven
A long-term follow-up study of patients with prosthetic joint infection of the hip treated at Universitaire Ziekenhuizen KU Leuven, currentl…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture [Phase 3]
Phase 3 trial comparing dual versus single-antibiotic impregnated cement in hemiarthroplasty for femoral neck fracture; the study is current…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Bacteriophage Therapy for Staphylococcus Lugdunensis Prosthetic Joint Infection [Phase 1, Phase 2]
A Phase 1/2 clinical trial at the University of Calgary is evaluating bacteriophage therapy for prosthetic joint infections of the hip cause…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Reduction of Bacterial Seeding in Total Shoulder Arthroplasty [NA]
An ongoing clinical trial is recruiting to evaluate strategies to reduce bacterial seeding during total shoulder arthroplasty to lower prost…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: The Effect of Peri-Operative Adjunctive Probiotics on Immunological Markers in Cases of Prosthetic Joint Infection of the Hip and Knee [NA]
A clinical trial update on whether peri-operative adjunctive probiotics affect immunological markers in prosthetic joint infection of the hi…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections.
A clinical trial update examining delafloxacin plasma and tissue concentrations in patients with soft tissue, mediastinitis, and bone/joint …
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Study of the Lived Experience of Patients With Prosthetic Joint Infection, Their Families, and Healthcare Professionals. Development of a Therapeutic Education Program for Patient Care (TEP).
This clinical trial studies the lived experiences of patients with prosthetic joint infection, their families, and healthcare professionals.…
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CLINICAL_TRIALS withdrawal · 2026-02-05Clinical Trial Update: Knee Prosthetic Joint Infection Antibiotic Elution
A knee prosthetic joint infection antibiotic elution trial (NCT06023238) sponsored by the University of Pittsburgh has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Treatment of the Infections on Osteo-articular Prostheses by 6 Versus 12 Weeks of Antibiotherapy [Phase 3]
Phase 3 trial comparing six weeks versus twelve weeks of antibiotic therapy for prosthetic joint infections has completed, with results inte…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection [Phase 2]
A Phase 2 clinical trial is evaluating TRL1068 for the treatment of prosthetic joint infections of the hip and knee. The study is currently …
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Metal Artifact Reduction Sequence MRI for Surgical Decision-Making in Infected Unicompartmental Knee Arthroplasty
Completed clinical trial evaluating Metal Artifact Reduction Sequence MRI to aid surgical decision-making in infected unicompartmental knee …
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Prosthetic Joint Infection : Lessons From Deceased Patients in Critical Care.
A clinical trial update on prosthetic joint infection focusing on lessons from deceased patients in critical care; the study is currently re…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Periprosthetic Joint Infections: Diagnostic Accuracy and Cost-effectiveness Analysis of Serum and Synovial Markers
This clinical trial assesses the diagnostic accuracy and cost-effectiveness of serum and synovial markers for prosthetic joint infection. Th…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Importance of Patient Selection for Treatment of Infected Total Knee Prosthesis
A completed clinical trial from University Hospital Strasbourg examines how patient selection influences treatment outcomes for infected tot…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee [Phase 4]
Phase 4 clinical trial evaluating whether probiotics can prevent recurrent prosthetic joint infection in the hip and knee; enrollment is by …
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: PCA Administration in Prosthetic Joint Infection [NA]
A clinical trial investigating PCA administration for Prosthetic Joint Infection is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: F18-MHF: Orthopedic Implants-Associated Infection Detection
A clinical trial evaluating F18-MHF for detection of orthopedic implant-associated infections in the knee is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement. [Phase 2, Phase 3]
A phase 2/3 clinical trial is evaluating an antibiotic-impregnated bone graft to reduce infections in hip replacement surgery, currently rec…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: OsteoArticular Sepsis in Intensive Care unitS
Clinical trial update indicating a study on osteoarticular sepsis in intensive care patients, recruiting in Paris, focusing on osteomyelitis…