Prion Disease

• CLINICAL_TRIALS research · 2026-04-24
  Clinical Trial Update: PrProfile: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ION717 [Phase 1, Phase 2]

  Clinical trial update for ION717 in prion disease, currently recruiting in Phase 1/2 to assess safety, tolerability, pharmacokinetics and ph…

• CLINICAL_TRIALS trial_result · 2026-04-17
  Clinical Trial Update: PrP-targeting siRNA Safety & Mechanism Study [Phase 1]

  Ongoing Phase 1 safety and mechanism study of a PrP-targeting siRNA for prion disease; the trial is currently recruiting.

• CLINICAL_TRIALS trial_result · 2015-04-07
  Clinical Trial Update: PRION-1: Quinacrine for Human Prion Disease [NA]

  PRION-1 is a completed clinical trial evaluating quinacrine for human prion disease.