Sclerosing Cholangitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-05-10Clinical Trial Update: Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis Despite Ursodeoxycholic Acid Therapy [Phase 3]
Phase 3 clinical trial evaluating 24 months of bezafibrate for primary sclerosing cholangitis with persistent cholestasis despite ursodeoxyc…
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CLINICAL_TRIALS trial_result · 2022-04-06Clinical Trial Update: A POC and Dose-Ranging Study of HTD1801 in PSC Patients [Phase 2]
A Phase 2 dose-ranging and proof-of-concept study of HTD1801 in Primary Sclerosing Cholangitis (PSC) has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis [Phase 2]
Phase 2 trial of low-dose all-trans retinoic acid in primary sclerosing cholangitis was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases [Phase 2]
Phase 2 clinical trial evaluating low-dose IL-2 to induce regulatory T cells in various autoimmune and inflammatory diseases; trial complete…
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: Vidofludimus Calcium for Primary Sclerosing Cholangitis [Phase 2]
Phase 2 clinical trial of vidofludimus calcium in primary sclerosing cholangitis completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Trial of High-dose Urso in Primary Sclerosing Cholangitis [Phase 2, Phase 3]
Phase 2/3 trial of high-dose ursodeoxycholic acid in primary sclerosing cholangitis was terminated with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-09-30Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Cilofexor in Adults With Normal and Impaired Hepatic Function [Phase 1]
Phase 1 study reporting pharmacokinetics and pharmacodynamics of cilofexor in adults with normal and impaired hepatic function; completed wi…
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis (PSC) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating the safety and efficacy of curcumin in patients with primary sclerosing cholangitis has completed with…
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CLINICAL_TRIALS trial_result · 2019-10-22Clinical Trial Update: Simtuzumab (GS-6624) in the Prevention of Progression of Liver Fibrosis in Adults With Primary Sclerosing Cholangitis (PSC) [Phase 2]
Phase 2 trial update for simtuzumab (GS-6624) in adults with primary sclerosing cholangitis (PSC) completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Fecal Microbiota Transplantation for the Treatment of Primary Sclerosing Cholangitis. [Phase 1, Phase 2]
Clinical trial update on fecal microbiota transplantation for primary sclerosing cholangitis (phases 1 and 2) completed with results posted …
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CLINICAL_TRIALS trial_result · 2019-05-03Clinical Trial Update: A Trial of BTT1023 in Patients With Primary Sclerosing Cholangitis [Phase 2]
Phase 2 clinical trial of BTT1023 in patients with primary sclerosing cholangitis has completed.
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CLINICAL_TRIALS trial_result · 2019-03-12Clinical Trial Update: Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Sclerosing Cholangitis Without Cirrhosis [Phase 2]
Phase 2 trial evaluating cilofexor in adults with primary sclerosing cholangitis without cirrhosis has completed; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: PERSEUS: Preliminary Efficacy and Safety of Cenicriviroc in Adult Participants With Primary Sclerosing Cholangitis [Phase 2]
Phase 2 trial update on cenicriviroc in adults with primary sclerosing cholangitis reports preliminary efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2018-09-21Clinical Trial Update: Primary Sclerosing Cholangitis With Oral Vancomycin by the Study of Its Antimicrobial and Immunomodulating Effects [Phase 3]
Phase 3 trial evaluating oral vancomycin for primary sclerosing cholangitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC) [Phase 2]
Phase 2 trial update for obeticholic acid in primary sclerosing cholangitis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis [Phase 1]
This document reports the completion of a Phase 1 safety and efficacy trial evaluating ursodeoxycholic acid in pediatric primary sclerosing …
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis [Phase 1]
This clinical trial update reports the completion of a Phase 1 pilot study evaluating budesonide in patients with primary sclerosing cholang…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing Cholangitis [Phase 2]
Open-label Phase 2 trial evaluating safety and efficacy of LUM001 in patients with primary sclerosing cholangitis (PSC) has completed with r…
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Detection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel Disease
This completed clinical trial evaluated stool DNA testing as a non-invasive method to detect advanced colorectal neoplasia in patients with …
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Digital SpyGlass Confirmed Common Bile Duct Stones Clearance Without Fluoroscopy [Phase 3]
The Phase 3 trial using the Digital SpyGlass system demonstrated clearance of common bile duct stones without fluoroscopy.
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Norursodeoxycholic Acid in the Treatment of Primary Sclerosing Cholangitis [Phase 2]
A Phase 2 clinical trial evaluating norursodeoxycholic acid for primary sclerosing cholangitis has completed. The trial was sponsored by Dr.…
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing Cholangitis [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating the combination of ursodeoxycholic acid (UDCA) and all-trans…
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Surgical Reconstruction in Ulcerative Colitis With Primary Sclerosing Cholangitis
A completed clinical trial evaluated surgical reconstruction for patients with ulcerative colitis and primary sclerosing cholangitis.
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin [Phase 1]
Phase 1 study assessing the effects of vancomycin on gastrointestinal microbiota in patients with Primary Sclerosing Cholangitis and Biliary…
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Compare Conventional Colonosocpy to Endoscopic AFI, NBI for Dysplasia Detection for Ulcerative Colitis & Cholangitis
A completed clinical trial comparing conventional colonoscopy to endoscopic autofluorescence imaging (AFI) and narrow-band imaging (NBI) for…