Central Nervous System Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Methotrexate, Cyclophosphamide, and Etoposide Phosphate Given With Osmotic Blood-Brain Barrier Disruption Plus Dexamethasone and Cytarabine in Treating Patients With Primary CNS Lymphoma [Phase 2]
A Phase 2 trial evaluates methotrexate, cyclophosphamide, and etoposide phosphate with osmotic blood-brain barrier disruption plus dexametha…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Neurotoxicity in Primary Central Nervous System Lymphoma (PCNSL): An International Observational Study of Cognition in Long Term Survivors
An international observational study on neurotoxicity and cognition in long-term survivors of Primary Central Nervous System Lymphoma has be…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Combined Immunochemotherapy Followed By Reduced Dose Radiation Therapy (RT) for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma [NA]
This clinical trial update describes results from a regimen of immunochemotherapy followed by reduced-dose radiation therapy in newly diagno…
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CLINICAL_TRIALS trial_result · 2017-03-13Clinical Trial Update: Phase II Study of Vismodegib in Patients With Refractory or Relapsed B-cell Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
Phase II study of vismodegib in refractory or relapsed B-cell lymphoma or chronic lymphocytic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma [Phase 2]
This clinical trial update notes the completion of a Phase 2 study evaluating idarubicin-based combined modality therapy for primary central…
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Study of High-Dose Rituximab With Temozolomide as Treatment for Primary Central Nervous System (CNS) Lymphoma [Phase 2]
A Phase 2 study evaluating high-dose rituximab with temozolomide for Primary Central Nervous System Lymphoma was terminated; results were po…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: Ketogenic Diet Adjunctive to HD-MTX Chemotherapy for Primary Central Nervous System Lymphoma [Phase 1, Phase 2]
This entry describes a Phase 1/Phase 2 clinical trial evaluating a ketogenic diet as an adjunct to high-dose methotrexate chemotherapy for p…
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Chemotherapy and Whole-Brain Radiation Therapy in Treating Patients With Primary Central Nervous System Non- Hodgkin's Lymphoma [Phase 2]
Phase 2 clinical trial evaluating chemotherapy plus whole-brain radiotherapy for primary central nervous system lymphoma (non-Hodgkin's). Th…
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Radiation Therapy and High-Dose Corticosteroids in Treating Older Patients With Primary CNS Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 clinical trial update evaluating the use of radiation therapy and high-dose corticosteroids in older patients with primary central n…
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CLINICAL_TRIALS trial_result · 2015-11-24Clinical Trial Update: Study of Tissue Samples From Patients With Glioma or Other Brain Tumors
A completed clinical trial update describing a study that collected tissue samples from patients with glioma or other brain tumors; central …
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CLINICAL_TRIALS trial_result · 2015-09-23Clinical Trial Update: Treatment of Recurrent Primary or Secondary Central Nervous System (CNS) Lymphoma With ALIMTA (Pemetrexed) [Phase 1]
A Phase 1 clinical trial assessing the safety and preliminary activity of pemetrexed (ALIMTA) for recurrent central nervous system lymphoma …
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CLINICAL_TRIALS trial_result · 2015-08-20Clinical Trial Update: Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Primary CNS Lymphoma [NA]
A completed clinical trial evaluating the combination of chemotherapy and rituximab in newly diagnosed primary central nervous system lympho…
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CLINICAL_TRIALS trial_result · 2015-07-21Clinical Trial Update: Treatment of Primary CNS Lymphoma [Phase 4]
Phase 4 clinical trial update for primary central nervous system lymphoma; current trial status is not provided.
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: Phase II Study Evaluating a Combination of Pegylated Liposomal Doxorubicin and Dexamethasone for the Treatment of Immunocompetent Patients With Cerebral Lymphoma Relapsed or Refractory to First-line Chemotherapy With High Dose Methotrexate (MTXHD) and / or High-dose Cytarabine. [Phase 2]
A Phase II trial evaluating the combination of pegylated liposomal doxorubicin and dexamethasone in immunocompetent patients with cerebral l…
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CLINICAL_TRIALS trial_result · 2015-04-13Clinical Trial Update: MT-R Followed by Autologous Stem Cells Transplantation in Newly-diagnosed Primary Central Nervous System Lymphoma [Phase 2]
This clinical trial update describes a Phase 2 study of MT-R followed by autologous stem cell transplantation in patients with newly diagnos…
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Phase II Trial of Combined Modality Treatment in Primary Central Nervous System Lymphoma [Phase 2]
ClinicalTrials.gov reports completion of a Phase II trial evaluating a combined modality treatment for primary central nervous system lympho…
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CLINICAL_TRIALS trial_result · 2015-02-16Clinical Trial Update: A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain Lymphoma [Phase 1]
A Phase 1 safety study evaluating the intrathecal combination of rituximab and methotrexate for central nervous system lymphoma and intraocu…
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CLINICAL_TRIALS trial_result · 2015-02-16Clinical Trial Update: Intrathecal Rituximab in Treating Patients With Recurrent CNS Lymphoma [Phase 1]
A Phase 1 trial evaluating intrathecal rituximab in patients with recurrent central nervous system lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2014-09-12Clinical Trial Update: Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Primary CNS Lymphoma [Phase 2]
Phase 2 study evaluating rituximab in combination chemotherapy for newly diagnosed primary central nervous system lymphoma; results have bee…
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CLINICAL_TRIALS trial_result · 2014-08-08Clinical Trial Update: A Study of MabThera (Rituximab) in Primary Central Nervous System Lymphoma. [Phase 2]
A Phase 2 study evaluating MabThera (rituximab) in primary central nervous system lymphoma was terminated. Results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-01-27Clinical Trial Update: Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating a combination of methotrexate, glucarpidase, and leucovorin in newly diagnosed primary central nervous system lym…
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CLINICAL_TRIALS trial_result · 2013-11-15Clinical Trial Update: Pemetrexed and Temozolomide in Treating Patients With Relapsed Primary Central Nervous System Lymphoma （PCNSL） [Phase 2]
Phase 2 clinical trial update evaluating pemetrexed plus temozolomide in relapsed primary central nervous system lymphoma. The current statu…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma [Phase 1]
Phase 1 trial evaluating Triapine (3-AP) in combination with gemcitabine in patients with advanced solid tumors or lymphoma has completed. I…
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CLINICAL_TRIALS trial_result · 2013-08-28Clinical Trial Update: Rituximab in Treating Patients With Refractory or Relapsed Primary CNS Lymphoma [Phase 2]
Phase 2 trial of Rituximab in patients with refractory or relapsed primary central nervous system lymphoma; the study was terminated and res…
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CLINICAL_TRIALS trial_result · 2013-06-24Clinical Trial Update: Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma [Phase 2]
A Phase 2 trial evaluating the combination of methotrexate and thiotepa for newly diagnosed primary central nervous system lymphoma has comp…