Central Nervous System Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-09-22Clinical Trial Update: Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating a combination regimen (methotrexate, mannitol, rituximab, and carboplatin) for newly diagnosed primar…
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CLINICAL_TRIALS trial_result · 2021-07-16Clinical Trial Update: A Trial to Compare Ibrutinib Versus Lenalidomide in Combination With MRE-chemotherapy for Adult Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) [Phase 2]
Phase 2 trial comparing ibrutinib versus lenalidomide in combination with MRE-chemotherapy for adult patients with recurrent or refractory p…
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: Rituximab,Zanubrutinib in Combination With Lenalidomide, Followed by Zanubrutinib or Lenalidomide Maintenance in Patients With Primary or Secondary CNS Lymphoma [Phase 2]
Phase 2 clinical trial evaluating rituximab, zanubrutinib, and lenalidomide with subsequent maintenance in CNS lymphoma.
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CLINICAL_TRIALS trial_result · 2021-05-24Clinical Trial Update: Phase II Study of Orelabrutinib Combined With PD-1 Inhibitor in Relapsed/Refractory Primary Central Nervous System Lymphoma [Phase 2]
Phase II study evaluating orelabrutinib in combination with a PD-1 inhibitor for relapsed/refractory primary CNS lymphoma is in progress wit…
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma [Phase 2]
Phase 2 trial evaluating rituximab, methotrexate, vincristine, procarbazine, and cytarabine with or without radiation for primary CNS lympho…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Efficacy of Lenalidomide With Rituximab in Refractory or Relapse of Primary Central Nervous System Lymphoma [Phase 2]
Phase 2 trial evaluating lenalidomide with rituximab in refractory or relapsed primary central nervous system lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL) [Phase 2]
Phase 2 trial of nivolumab in relapsed/refractory primary CNS lymphoma and primary testicular lymphoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: A Study of F520 in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) or Secondary Central Nervous System Lymphoma (SCNSL) [Phase 2]
Phase 2 clinical trial update for F520 in relapsed/refractory PCNSL and SCNSL.
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CLINICAL_TRIALS trial_result · 2020-09-09Clinical Trial Update: Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL [Phase 2, Phase 3]
A study evaluating R-IDARAM and intrathecal immunochemotherapy for elderly patients with primary central nervous system lymphoma is in Phase…
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CLINICAL_TRIALS trial_result · 2020-09-09Clinical Trial Update: Treatment of PCNSL With R-IDARAM and Intrathecal Immunochemotherapy [Phase 2, Phase 3]
Phase 2/3 trial update for treatment of primary central nervous system lymphoma using R-IDARAM and intrathecal immunochemotherapy.
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CLINICAL_TRIALS trial_result · 2020-08-18Clinical Trial Update: A Phase II Trail of Chidamide ,Rituximab and Methotrexate in Lymphoma Patients [Phase 2]
Phase II trial evaluating chidamide, rituximab, and methotrexate in Central Nervous System lymphoma is ongoing with status unknown.
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CLINICAL_TRIALS trial_result · 2020-06-05Clinical Trial Update: R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL：a Multicenter Phase Ib/II Stuty [Phase 1, Phase 2]
A multicenter phase Ib/II trial evaluating R2-MTX with lenalidomide maintenance for newly diagnosed primary central nervous system lymphoma …
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Open Randomized Prospective Clinical Study of R-FPD Versus R-MAD Regimen in the Treatment of Primary Central Nervous System Lymphoma [Phase 4]
Open randomized prospective Phase 4 trial comparing R-FPD to R-MAD in primary CNS lymphoma.
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CLINICAL_TRIALS trial_result · 2019-08-26Clinical Trial Update: IBER Salvage Treatment Followed by Ibrutinib Maintenance for Relapsed or Refractory PCNSL [Phase 2]
Phase 2 trial evaluating salvage treatment with IBER followed by Ibrutinib maintenance for relapsed or refractory primary central nervous sy…
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CLINICAL_TRIALS trial_result · 2019-07-09Clinical Trial Update: PQR309 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma [Phase 2]
Phase 2 clinical trial update for PQR309 in relapsed or refractory primary central nervous system lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2019-01-22Clinical Trial Update: Comparison of Creatinine Clearance Calculation for Estimation of GFR in Patients Receiving HD Methotrexate
The trial update compares creatinine clearance calculations for estimating GFR in patients receiving high-dose methotrexate, in the context …
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CLINICAL_TRIALS trial_result · 2018-11-07Clinical Trial Update: BUCYE Conditioning Regimen for PCNSL Undergoing Auto-HSCT [Phase 2, Phase 3]
Clinical trial update for a BUCYE conditioning regimen in primary CNS lymphoma patients undergoing autologous HSCT, spanning Phase 2 and Pha…
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CLINICAL_TRIALS trial_result · 2018-09-04Clinical Trial Update: Rituximab, Temozolomide, and Methylprednisolone in Treating Patients With Recurrent Primary CNS Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 clinical trial investigating rituximab, temozolomide, and methylprednisolone for recurrent primary CNS non-Hodgkin's lymphoma; the s…
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating a combination of chemotherapy, a monoclonal antibody, and radiation therapy for primary central nervou…
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CLINICAL_TRIALS trial_result · 2018-01-08Clinical Trial Update: Bendamustine-based Combination Therapy for PCNSL [Phase 2]
A Phase 2 clinical trial update evaluating bendamustine-based combination therapy for primary central nervous system lymphoma (PCNSL).
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL) [Phase 2]
Phase 2 clinical trial of buparlisib (BKM120) in patients with recurrent/refractory primary central nervous system lymphoma and recurrent/re…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma
A completed clinical trial evaluating brain lesions in HIV-infected patients to aid in the diagnosis of primary central nervous system lymph…
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma [Phase 2]
Phase 2 trial update evaluating rituximab with combination chemotherapy in primary central nervous system lymphoma; study terminated with re…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer [NA]
Clinical trial update reports results of a conditioning regimen using fludarabine and total-body irradiation followed by donor stem cell tra…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma [Phase 2]
This report summarizes a Phase 2 trial evaluating a multi-agent regimen of methotrexate, procarbazine, lomustine, dexamethasone, and cytarab…