Central Nervous System Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Diagnosis; Objective RespOnse; THErApy [NA]
A clinical trial sponsored by IRCCS San Raffaele is currently recruiting for Primary Central Nervous System Lymphoma; no results reported ye…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Rituximab, Acalabrutinib, and Durvalumab (RAD) in Primary CNS Lymphoma. [Phase 1]
A Phase 1 clinical trial update for a combination of rituximab, acalabrutinib, and durvalumab (RAD) in primary central nervous system lympho…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Rituximab, Methotrexate, and Tepadina Induction Followed by Etoposide and Cytarabine Consolidation in Primary Central Nervous System Lymphoma [NA]
Clinical trial update noting ongoing recruitment for a regimen of rituximab, methotrexate, and thiotepa induction followed by etoposide and …
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Tirabrutinib Maintenance Versus Placebo in Patients With Primary CNS Lymphoma in Complete Remission (JCOG2104) [Phase 2]
A Phase 2 clinical trial evaluating tirabrutinib as maintenance therapy versus placebo in patients with primary central nervous system lymph…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Rituximab, Lenalidomide Combined With Methotrexate and Temozolomide For Primary Central Nervous System Lymphoma [Phase 2]
A Phase 2 clinical trial is evaluating a four-drug combination (rituximab, lenalidomide, methotrexate, and temozolomide) for primary central…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Methotrexate or Thiotepa Combined With R-CHOP and Orelabrutinib in CNSL Patients [Phase 2]
A Phase 2 clinical trial is evaluating methotrexate or thiotepa in combination with R-CHOP and orelabrutinib for central nervous system lymp…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Relma-cel Followed by Tislelizumab for the Treatment of Relapsed/Refractory CNS Large B-Cell Lymphoma [Phase 2]
This clinical trial update describes a Phase 2 study of Relma-cel followed by Tislelizumab for relapsed/refractory central nervous system ly…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Rituximab-Methotrexate-Temozolomide-Thiotepa (RMTT) Regimen As First-line Therapy for PCNS DLBCL [NA]
Clinical trial update for a Rituximab-Methotrexate-Temozolomide-Thiotepa regimen as first-line therapy for primary central nervous system ly…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Adjusted High-dose Chemotherapy With Autologous Stem Cell Transplant vs. Conventional Immunochemotherapy in Elderly PCNSL Patients [Phase 3]
Phase 3 clinical trial comparing adjusted high-dose chemotherapy with autologous stem cell transplant versus conventional immunochemotherapy…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Tafasitamab Plus Lenalidomide in Relapsed CNS Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating tafasitamab plus lenalidomide for relapsed central nervous system lymphomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: [90Y]Y-PTT Endoradiotherapy in CNS Lymphoma Patients [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating [90Y]Y-PTT Endoradiotherapy for primary central nervous system lymphoma is currently recruiting, sponsor…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Human CD19-CD22 Targeted T Cells Injection for Refractory/Relapsed Central Nervous System Leukemia/Lymphoma Patients [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating autologous CD19-CD22 targeted T cells in patients with refractory or relapsed central nervous system…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: CtDNA for Early Response Assessment in PCNSL Treated with 1st Line Curative Intent (NLG-PCNSL-01)
This clinical trial update describes the NLG-PCNSL-01 study evaluating circulating tumor DNA for early response assessment in primary centra…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: NB02 (Poseltinib) Combined Rituximab and Lenalidomide in R/R PCNSL [Phase 2]
A Phase 2 clinical trial evaluating NB02 (Poseltinib) in combination with Rituximab and Lenalidomide for relapsed/refractory Primary Central…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Real-World Evidence of Effectiveness and Safety of Tirabrutinib in Patients with Relapsed or Refractory Primary Central Nervous System Lymphoma in Taiwan: a Nationwide Study
A nationwide real-world study in Taiwan assesses the effectiveness and safety of Tirabrutinib for relapsed or refractory Primary Central Ner…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Camrelizumab for Patients with Recurrent Primary Central Nervous System Lymphoma (PCNSL) [Phase 2]
Phase 2 trial of camrelizumab for recurrent primary central nervous system lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: A Study of Pomadomide in Combination With Rituximab and Methotrexate for Newly-diagnosed Primary Central Nervous System Lymphoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating Pomadomide in combination with Rituximab and Methotrexate for newly diagnosed primary central…
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CLINICAL_TRIALS research · 2024-06-06Clinical Trial Update: A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL [NA]
The document describes a clinical study evaluating the safety and efficacy of the ZRMT Regimen for Primary Central Nervous System Lymphoma, …
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CLINICAL_TRIALS research · 2019-02-05Clinical Trial Update: Cranial Radiotherapy or Intensive Chemotherapy With Hematopoietic Stem Cell Rescue for Primary Central Nervous System Lymphoma in Young Patients [Phase 2]
Phase 2 trial evaluating cranial radiotherapy or intensive chemotherapy with hematopoietic stem cell rescue for young patients with primary …
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CLINICAL_TRIALS research · 2016-10-14Clinical Trial Update: Temozolomide in Treatment of Patients With Primary Central Nervous System Lymphoma [Phase 2]
A Phase 2 clinical trial is evaluating temozolomide for primary central nervous system lymphoma, with the current status listed as UNKNOWN.
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CLINICAL_TRIALS research · 2016-06-22Clinical Trial Update: Study on Pembrolizumab for Recurrent Primary Central Nervous System Lymphoma (PCNSL) [Phase 2]
A Phase 2 clinical trial is evaluating pembrolizumab for recurrent Primary Central Nervous System Lymphoma. Current status is unknown.
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CLINICAL_TRIALS research · 2015-08-25Clinical Trial Update: High-dose Chemotherapy and ASCT or Consolidating Conventional Chemotherapy in Primary CNS Lymphoma [Phase 3]
A Phase 3 clinical trial comparing high-dose chemotherapy with autologous stem cell transplantation to consolidating conventional chemothera…
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CLINICAL_TRIALS research · 2013-04-17Clinical Trial Update: Temsirolimus in Recurrent Primary Central Nervous System (CNS) Lymphoma [Phase 2]
This document reports a Phase 2 clinical trial update for temsirolimus in recurrent primary central nervous system lymphoma.
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CLINICAL_TRIALS research · 2009-11-17Clinical Trial Update: Freiburg ZNS-NHL Study [Phase 2]
A Phase 2 clinical trial at University Hospital Freiburg is investigating primary central nervous system lymphoma, with the study status cur…
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CLINICAL_TRIALS research · 2009-10-05Clinical Trial Update: Methotrexate-based Chemo-immunotherapy Followed by Maintenance Therapy for Patients > 65 Years With Central Nervous System (CNS)-Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating methotrexate-based chemo-immunotherapy followed by maintenance therapy in patients over 65 with primary …