Aldosteronism
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of QLS1410 in the Treatment of Primary Aldosteronism. [Phase 2]
Phase 2 clinical trial update for QLS1410 in primary aldosteronism; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
This ClinicalTrials.gov study investigates the clinical and molecular characteristics of primary aldosteronism in Black participants, focusi…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: A Phase II Clinical Study on the Efficacy and Safety of HRS-1780 in Participants With Primary Aldosteronism [Phase 2]
A Phase II clinical trial evaluating the efficacy and safety of HRS-1780 in patients with primary aldosteronism has been announced, with rec…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Steroids-Based Screening for Primary Aldosteronism
A clinical trial is currently recruiting to evaluate steroids-based screening for primary aldosteronism, with hypertension as a related cond…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: REnin-guided TherApy With MinEralocorticoid Receptor Antagonists in Primary Aldosteronism - Feasibility Study [NA]
This feasibility study evaluates renin-guided therapy using mineralocorticoid receptor antagonists in patients with primary aldosteronism; t…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Radiofrequency Ablation Versus Adrenalectomy for Adenoma in Patients With Primary Aldosteronism and Hypertension [NA]
A clinical trial compares radiofrequency ablation to adrenalectomy for Conn adenoma–related primary aldosteronism and hypertension. The stud…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: A Study of CIN-107 in Adults With Primary Aldosteronism [Phase 2]
Phase 2 clinical trial of CIN-107 in adults with primary aldosteronism completed; results posted.
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)
A Cleveland Clinic-sponsored trial evaluating the aldosterone-renin ratio (ARR) test for increasing detection of primary aldosteronism has c…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Randomised Trial Comparing Thermal Ablation With Adrenalectomy in the Treatment of Unilateral Asymmetric PA [NA]
A randomized trial comparing thermal ablation with adrenalectomy for unilateral primary aldosteronism is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: 68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Diagnosing Unilateral Subtype of Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion (PREDICT) [NA]
Clinical trial evaluating 68Ga-Pentixafor PET/CT versus adrenal vein sampling for diagnosing unilateral primary aldosteronism with autonomou…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Prognosis of Primary Aldosteronism: A Prospective Cohort Study
A prospective cohort study from Xinjiang Medical University is currently recruiting to investigate the prognosis of primary aldosteronism.
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Genetic Predisposition to High Blood Pressure [NA]
An ongoing study from Linköping University investigates genetic predisposition to hypertension, with enrollment by invitation, and involves …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Trial of Aldosterone-hybrid SteRoid for Guiding curablE Treatment of Primary Aldosteronism (TARGET-PA) [NA]
This entry describes the TARGET-PA trial evaluating an aldosterone-hybrid steroid to guide curable treatment of primary aldosteronism; the s…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: The Association Between Primary Aldosteronism and Cognitive Dysfunction
A clinical trial from Xinjiang Medical University is investigating the association between primary aldosteronism and cognitive dysfunction, …
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Sequential Combined Versus Single-Strategy Adrenal Venous Sampling for Primary Aldosteronism(SCOPE) [NA]
This clinical trial update reports a study (SCOPE) comparing sequential combined versus single-strategy adrenal venous sampling for primary …
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: The Effect of SAAE on Vascular Endothelial Function in PA Patients
This clinical trial update notes that the study assessing the effect of SAAE on vascular endothelium in primary aldosteronism patients is cu…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Multi-omics Studies of Primary Aldosteronism
A clinical trial exploring multi-omics approaches to primary aldosteronism, currently in recruiting status at Peking University First Hospit…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: 11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours [Phase 2, Phase 3]
This clinical trial is evaluating 11C-Metomidate PET/CT imaging in Phase 2/3 to assess endocrine hypertension and characterize adrenal tumor…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Prospective Phenotyping of Autonomous Aldosterone Secretion
This clinical trial update describes a prospective study to phenotype autonomous aldosterone secretion, sponsored by Brigham and Women's Hos…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Overnight Dexamethasone in Primary Aldosteronism Screening
Ongoing clinical trial evaluating overnight dexamethasone as a screening test for primary aldosteronism, currently recruiting at the Medical…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
This document reports enrollment status for a comparative study of perioperative cardiac injury in patients with functional adrenal tumors, …
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism [Phase 4]
A Phase 4 clinical trial reports on the efficacy and safety of finerenone for treating primary aldosteronism.
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Efficacy of Spironolactone Combined With Antihypertensive Drugs in Patients With Primary Aldosteronism
A clinical trial evaluating whether spironolactone together with other antihypertensive medications improves outcomes in patients with prima…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Effect of Anti-hypertensive Medications on the Diagnostic Accuracy in Primary Aldosteronism
A completed clinical trial from Chongqing Medical University evaluated whether anti-hypertensive medications influence the diagnostic accura…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion
A clinical trial is recruiting to determine how often adrenal insufficiency occurs after surgery in patients with primary aldosteronism, wit…