Aldosteronism
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: A Phase II Clinical Study on the Efficacy and Safety of HRS-1780 in Participants With Primary Aldosteronism [Phase 2]
A Phase II clinical trial evaluating the efficacy and safety of HRS-1780 in patients with primary aldosteronism has been announced, with rec…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: A Study of CIN-107 in Adults With Primary Aldosteronism [Phase 2]
Phase 2 clinical trial of CIN-107 in adults with primary aldosteronism completed; results posted.
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)
A Cleveland Clinic-sponsored trial evaluating the aldosterone-renin ratio (ARR) test for increasing detection of primary aldosteronism has c…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism [Phase 4]
A Phase 4 clinical trial reports on the efficacy and safety of finerenone for treating primary aldosteronism.
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Effect of Anti-hypertensive Medications on the Diagnostic Accuracy in Primary Aldosteronism
A completed clinical trial from Chongqing Medical University evaluated whether anti-hypertensive medications influence the diagnostic accura…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: The Diagnostic Performance of 24-hour Urinary Aldosterone for Primary Aldosteronism
A completed clinical trial assessing how well 24-hour urinary aldosterone performs as a diagnostic test for primary aldosteronism in hyperte…
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: Calcium Channel Blockade in Primary Aldosteronism [Phase 2]
Phase 2 trial evaluating calcium channel blockade for primary aldosteronism has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Prospective Evaluation of Confirmatory Testing for Primary Aldosteronism
A completed prospective study evaluating confirmatory testing strategies for diagnosing primary aldosteronism.
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: DP13 - A Phase II Study in Patients With Primary Aldosteronism [Phase 2]
DP13, a drug developed by Damian Pharma AG, completed a Phase II study in patients with primary aldosteronism. Results from the Phase II tri…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Super Selective Adrenal Artery Embolization for Primary Aldosteronism: a Prospective Cohort Study(SAAE-PA)
This entry reports a recruiting clinical trial (NCT06513676) evaluating super selective adrenal artery embolization as a treatment for prima…
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CLINICAL_TRIALS trial_result · 2024-07-15Clinical Trial Update: The Plasma Metabolomics Profiling of Primary Aldosteronism
A completed clinical trial investigating plasma metabolomics profiling in primary aldosteronism and related hypertensive conditions.
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: Effect of a Proposed Cav1.3 Inhibitor in Primary Aldosteronism [NA]
This clinical trial update reports that the study evaluating a proposed Cav1.3 inhibitor for primary aldosteronism has completed. The sponso…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Efficacy and Safety of Finerenone in Patients With Primary Aldosteronism [Phase 4]
A Phase 4 clinical trial evaluates finerenone in patients with primary aldosteronism. The study has completed, reporting on efficacy and saf…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Outcome of 68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Primary Aldosteronism [NA]
A clinical trial is evaluating whether 68Ga-Pentixafor PET/CT provides advantages over adrenal vein sampling for diagnosing primary aldoster…
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CLINICAL_TRIALS trial_result · 2023-12-11Clinical Trial Update: Efficacy and Safety of Finerenone vs. Spironolactone in Patients With Primary Aldosteronism [Phase 4]
A Phase 4 trial update comparing finerenone to spironolactone in patients with primary aldosteronism, focusing on efficacy and safety.
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: Comparing the Efficacy and Safety of Finerenone and Spironolactone in the Treatment of Primary Aldosteronism [Phase 4]
Phase 4 trial comparing finerenone and spironolactone for primary aldosteronism and hypertension.
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CLINICAL_TRIALS trial_result · 2019-07-08Clinical Trial Update: Adrenal Artery Ablation Treats Primary Aldosteronism [Phase 3]
A Phase 3 clinical trial on adrenal artery ablation for treating primary aldosteronism has completed.
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CLINICAL_TRIALS trial_result · 2019-01-09Clinical Trial Update: Open-label Study on Treatment of Primary Aldosteronism With Everolimus [Phase 2]
Phase 2 open-label trial evaluating everolimus for treatment of primary aldosteronism has completed.
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: Adrenal Artery Ablation for Primary Aldosteronism [Phase 3]
A Phase 3 clinical trial update on adrenal artery ablation for primary aldosteronism and hypertension is ongoing, with status currently unkn…
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: Rapid Cortisol Assay in Adrenal Vein Sampling [NA]
Clinical trial update on using a rapid cortisol assay during adrenal vein sampling for primary aldosteronism due to an aldosterone-producing…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Arterial Stiffness Index as a Predictor of Surgically Correctable Primary Aldosteronism [NA]
A completed clinical trial evaluated whether arterial stiffness index could predict surgically curable primary aldosteronism, often due to a…
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CLINICAL_TRIALS trial_result · 2016-11-11Clinical Trial Update: Optimizing Diagnosis Of Primary Aldosteronism
This ClinicalTrials.gov entry reports the completion of a study evaluating diagnostic approaches for primary aldosteronism conducted by Chon…
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Primary Aldosteronism in General Practice: Organ Damage, Epidemiology and Treatment
A completed clinical trial from Radboud University Medical Center examining organ damage, epidemiology, and treatment of primary aldosteroni…
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: The Effect of Disease-specific Treatment on Bone Turnover Markers in Patients With Primary Aldosteronism
A completed clinical trial evaluating how disease-specific treatment affects bone turnover markers in patients with Primary aldosteronism.
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CLINICAL_TRIALS trial_result · 2015-07-16Clinical Trial Update: SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan. [Phase 3]
A randomized Phase 3 trial (SPARTACUS) comparing adrenal vein sampling versus CT scan for subtyping primary aldosteronism has completed.