Aldosteronism
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of QLS1410 in the Treatment of Primary Aldosteronism. [Phase 2]
Phase 2 clinical trial update for QLS1410 in primary aldosteronism; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
This ClinicalTrials.gov study investigates the clinical and molecular characteristics of primary aldosteronism in Black participants, focusi…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Steroids-Based Screening for Primary Aldosteronism
A clinical trial is currently recruiting to evaluate steroids-based screening for primary aldosteronism, with hypertension as a related cond…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: REnin-guided TherApy With MinEralocorticoid Receptor Antagonists in Primary Aldosteronism - Feasibility Study [NA]
This feasibility study evaluates renin-guided therapy using mineralocorticoid receptor antagonists in patients with primary aldosteronism; t…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Radiofrequency Ablation Versus Adrenalectomy for Adenoma in Patients With Primary Aldosteronism and Hypertension [NA]
A clinical trial compares radiofrequency ablation to adrenalectomy for Conn adenoma–related primary aldosteronism and hypertension. The stud…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Randomised Trial Comparing Thermal Ablation With Adrenalectomy in the Treatment of Unilateral Asymmetric PA [NA]
A randomized trial comparing thermal ablation with adrenalectomy for unilateral primary aldosteronism is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: 68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Diagnosing Unilateral Subtype of Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion (PREDICT) [NA]
Clinical trial evaluating 68Ga-Pentixafor PET/CT versus adrenal vein sampling for diagnosing unilateral primary aldosteronism with autonomou…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Prognosis of Primary Aldosteronism: A Prospective Cohort Study
A prospective cohort study from Xinjiang Medical University is currently recruiting to investigate the prognosis of primary aldosteronism.
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Genetic Predisposition to High Blood Pressure [NA]
An ongoing study from Linköping University investigates genetic predisposition to hypertension, with enrollment by invitation, and involves …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Trial of Aldosterone-hybrid SteRoid for Guiding curablE Treatment of Primary Aldosteronism (TARGET-PA) [NA]
This entry describes the TARGET-PA trial evaluating an aldosterone-hybrid steroid to guide curable treatment of primary aldosteronism; the s…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: The Association Between Primary Aldosteronism and Cognitive Dysfunction
A clinical trial from Xinjiang Medical University is investigating the association between primary aldosteronism and cognitive dysfunction, …
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Sequential Combined Versus Single-Strategy Adrenal Venous Sampling for Primary Aldosteronism(SCOPE) [NA]
This clinical trial update reports a study (SCOPE) comparing sequential combined versus single-strategy adrenal venous sampling for primary …
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: The Effect of SAAE on Vascular Endothelial Function in PA Patients
This clinical trial update notes that the study assessing the effect of SAAE on vascular endothelium in primary aldosteronism patients is cu…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Multi-omics Studies of Primary Aldosteronism
A clinical trial exploring multi-omics approaches to primary aldosteronism, currently in recruiting status at Peking University First Hospit…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: 11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours [Phase 2, Phase 3]
This clinical trial is evaluating 11C-Metomidate PET/CT imaging in Phase 2/3 to assess endocrine hypertension and characterize adrenal tumor…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Prospective Phenotyping of Autonomous Aldosterone Secretion
This clinical trial update describes a prospective study to phenotype autonomous aldosterone secretion, sponsored by Brigham and Women's Hos…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Overnight Dexamethasone in Primary Aldosteronism Screening
Ongoing clinical trial evaluating overnight dexamethasone as a screening test for primary aldosteronism, currently recruiting at the Medical…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
This document reports enrollment status for a comparative study of perioperative cardiac injury in patients with functional adrenal tumors, …
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Efficacy of Spironolactone Combined With Antihypertensive Drugs in Patients With Primary Aldosteronism
A clinical trial evaluating whether spironolactone together with other antihypertensive medications improves outcomes in patients with prima…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion
A clinical trial is recruiting to determine how often adrenal insufficiency occurs after surgery in patients with primary aldosteronism, wit…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: PETAL Trial: Impact of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Primary Aldosteronism [NA]
Clinical trial update for the PETAL study evaluating whether Gallium-68 Pentixafor PET-CT improves surgical outcomes in primary aldosteronis…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Diagnosing Variable Primary Aldosteronism.
A clinical trial update indicating a study on diagnosing variable primary aldosteronism is currently recruiting. The study involves conditio…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Tissue Sodium Quantification in Patients With Primary Aldosteronism: See Sodium to Treat
This clinical trial update reports ongoing recruitment for a study assessing tissue sodium quantification in patients with primary aldostero…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Continuous Steroid Monitoring in Interstitial Fluid With Wearable and Nanoparticle-enhanced Biosensors for Improved Management of Adrenal Disorders [NA]
This study investigates continuous monitoring of steroid levels in interstitial fluid using a wearable sensor platform and nanoparticle-enha…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: The Effect of SAAE on Ventricular Remodeling in PA Patients [NA]
A clinical trial is investigating the effect of SAAE on ventricular remodeling in patients with primary aldosteronism; the study is currentl…