Premature Rupture of Membranes
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: I.V Papavrine for Labor Induction in Term PROM [Phase 4]
Phase 4 clinical trial evaluating intravenous papaverine for labor induction in term premature rupture of membranes is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: PPROM Registry (Preterm Premature Rupture of Membranes)
A PPROM Registry study is currently recruiting to collect real-world data on outcomes of preterm premature rupture of membranes.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: PGE2 Followed by Oxytocin vs Oxytocin in Term PROM (POXY-PROM) [NA]
A recruiting clinical trial comparing dinoprostone (PGE2) followed by oxytocin versus oxytocin alone for labor induction in term pregnancies…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: HOME: Home Monitoring of High-risk Pregnancies
HOME: Home Monitoring of High-risk Pregnancies is currently enrolling by invitation. The study focuses on hypertensive disorders of pregnanc…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Intervention for Fear of Childbirth in High-Risk Pregnant Women [NA]
A completed clinical trial evaluating an intervention to reduce fear of childbirth in high-risk pregnant women.
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Early V/S Delayed Induction of Labour in Patients With Prelabour Rupture of Membranes [NA]
A ClinicalTrials.gov entry reports the completion of a study comparing early versus delayed induction of labor in women with premature ruptu…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Cranberry, Hibiscus, and Vitamin C Extracts Versus Placebo in Latency of Premature Rupture of Membranes. [NA]
A completed clinical trial compared cranberry, hibiscus, and vitamin C extracts against placebo to evaluate their effect on latency of labor…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: PROMMO Trial: Oral Misoprostol vs IV Oxytocin [EARLY_Phase 1]
The study is a completed early-phase 1 trial comparing oral misoprostol with IV oxytocin for management of premature rupture of membranes.
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor [NA]
Clinical trial update describing a study comparing two prophylactic antibiotic protocols in pregnant women with term prolonged pre-labor rup…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Vaginal Probiotics During Pregnancy After Premature (24-32 Weeks of Gestation) Preterm Rupture of Membranes [NA]
A not-yet-recruiting clinical trial assessing vaginal probiotics in pregnant individuals with a history of preterm rupture of membranes betw…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age [Phase 4]
This ClinicalTrials.gov update describes a Phase 4 study evaluating outpatient antibiotics for pregnancies affected by previable rupture of …
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Group B Streptococcus Infection and PROM Incidince
Assiut University is conducting a clinical trial investigating Group B streptococcal infection and premature rupture of membranes; the study…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Dilapan-S®: A Multicenter US E-registry
A multicenter US electronic registry update for the Dilapan-S device in obstetric indications; the registry is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Effects of Acupuncture in Spontaneous Rapture of Membranes: Applicability and Effectiveness [NA]
A completed clinical trial evaluated the applicability and effectiveness of acupuncture for spontaneous rupture of membranes in pregnancy, i…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Magnesium Sulphate in Premature Rupture of Membranes
A clinical trial update from Assiut University evaluating magnesium sulfate for premature rupture of membranes; the study is not yet recruit…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Pitocin or Oral Misoprostol for PROM IOL [Phase 4]
Phase 4 trial comparing Pitocin (oxytocin) versus oral misoprostol for induction of labor after premature rupture of membranes has completed…
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CLINICAL_TRIALS trial_result · 2023-07-25Clinical Trial Update: PeRinatal Outcomes With ACTive Versus Expectant Management of Women With Pre-labor Rupture Of Membranes [Phase 3]
A Phase 3 clinical trial comparing active management versus expectant management for pre-labor rupture of membranes to assess perinatal outc…
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: Cervical Ripening in Premature Rupture of Membranes [NA]
Clinical trial update for cervical ripening in the setting of premature rupture of membranes; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-09-24Clinical Trial Update: FOLCROM Trial: Foley Catheter in Rupture of Membranes [NA]
Completed clinical trial (FOLCROM Trial: Foley Catheter in Rupture of Membranes) with results posted.
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CLINICAL_TRIALS trial_result · 2018-04-25Clinical Trial Update: PROMComplete for Determination of Rupture of Fetal Membranes
Clinical trial update for PROMComplete, a diagnostic test intended to determine rupture of the fetal membranes, sponsored by Pro-Lab Diagnos…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial. [Phase 1, Phase 2]
Clinical trial investigating progesterone for managing preterm premature rupture of membranes (PPROM) across Phase 1 and Phase 2; completed …
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CLINICAL_TRIALS trial_result · 2018-02-19Clinical Trial Update: Cook Balloon Versus Propess After 12 Hours of Rupture of Membranes [Phase 4]
A Phase 4 clinical trial comparing Cook Balloon to Propess for management after 12 hours of membrane rupture (PROM). Status is UNKNOWN.
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CLINICAL_TRIALS research · 2017-07-12Clinical Trial Update: Urea and Creatinine Level in Vaginal Fluid as a Predicator for Length of Latency Period in Prelabour Membranes Rupture
A clinical trial update examining whether urea and creatinine levels in vaginal fluid can predict the length of the latency period after pre…
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CLINICAL_TRIALS research · 2017-07-11Clinical Trial Update: The Use of Quantitative Pregnancy Test in Amniotic Fluid as a Diagnostic Tool for Rupture of Fetal Membranes [NA]
This clinical trial update reports the completion of a study evaluating the use of a quantitative pregnancy test in amniotic fluid as a diag…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Predictive Score for Neonatal Mortality for Women With Premature Rupture of Membranes Between 22 and 28 Weeks of Gestation
This clinical trial (NCT03108404) evaluates a predictive score for neonatal mortality in women with preterm premature rupture of membranes b…