Premature Ovarian Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-20Clinical Trial Results: The Impact of Granulocyte Colony Stimulating Factor on Premature Ovarian Insufficiency [Phase 2]
Phase 2 trial assessing the impact of Granulocyte Colony Stimulating Factor on Premature Ovarian Insufficiency with results posted.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This clinical trial update notes that enrollment is ongoing for an intra-ovarian Muse cell injection (Muse cell therapy) aimed at alleviatin…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Long Term Follow up Patients With Premature Ovarian Failure ex Vivo Gene Therapy
Clinical trial NCT04675970 presents long-term follow-up data for patients with primary ovarian insufficiency and premature ovarian failure t…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Cryopreservation of Ovarian Tissue [NA]
Clinical trial on cryopreservation of ovarian tissue to preserve fertility in cancer patients and those at risk of premature ovarian failure…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Evolution of Sexual Life Quality of Women With POI Before and After Introduction of Hormone Replacement Therapy [NA]
This trial studies whether hormone replacement therapy improves sexual life quality in women with Premature Ovarian Failure; recruitment is …
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Autologous Heterotopic Fresh Ovarian Graft in Woman With LACC Eligible for Pelvic Radiotherapy Treatment. [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous heterotopic fresh ovarian grafting in women with locally advanced cervical cancer eligible for pelvic …
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Safety and Efficacy of Autologous Adipose-Derived Regenerative Cells (ADRCs) Injection for Improving Diminished Ovarian Reserve [NA]
Clinical trial evaluating safety and efficacy of autologous adipose-derived regenerative cells (ADRCs) injections to improve diminished ovar…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: The Impact of Granulocyte Colony Stimulating Factor on Premature Ovarian Insufficiency [Phase 2]
Phase 2 trial evaluating the impact of granulocyte colony-stimulating factor on primary ovarian insufficiency and premature ovarian failure;…
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CLINICAL_TRIALS other · 2025-01-28Clinical Trial Update: The Use of Expandeded Mesenchymal Stromal Cells (MSC) in Premature Ovarian Failure (POF) in Adult Humans [Phase 1]
Phase 1 clinical trial evaluating expanded mesenchymal stromal cells for premature ovarian failure in adult women; the study is currently ac…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients [Phase 2, Phase 3]
Clinical trial evaluating autologous platelet-rich plasma (PRP) infusion to restore ovarian function in women with premature ovarian failure…
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Prevention of Chemotherapy-Induced Ovarian Failure With Goserelin in Premenopausal Lymphoma Patients [Phase 2]
Phase 2 trial evaluating goserelin to prevent chemotherapy-induced ovarian failure in premenopausal lymphoma patients.
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CLINICAL_TRIALS trial_result · 2024-01-11Clinical Trial Update: Intra-ovarian Injection of MSC-EVs in Idiopathic Premature Ovarian Failure [Phase 1, Phase 2]
Clinical trial investigating intra-ovarian injection of mesenchymal stem cell-derived extracellular vesicles for idiopathic premature ovaria…
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CLINICAL_TRIALS trial_result · 2021-09-21Clinical Trial Update: Filgrastim for Premature Ovarian Insufficiency [Phase 4]
Phase 4 clinical trial update for filgrastim in premature ovarian insufficiency has completed.
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Ovarian Injection of PRP (Platelet -Rich Plasma) Vs Normal Saline in Premature Ovarian Insufficiency [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing ovarian injection of platelet-rich plasma to normal saline in premature ovarian insufficiency is in ear…
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: Stem Cell Therapy and Growth Factor Ovarian in Vitro Activation [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating stem cell therapy and growth factors for ovarian activation in menopause-related conditions and prema…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Transplantation of HUC-MSCs With Injectable Collagen Scaffold for POF [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating transplantation of human umbilical cord-derived mesenchymal stem cells with an injectable collagen sca…
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CLINICAL_TRIALS research · 2018-05-24Clinical Trial Update: Autologous Bone Marrow Stem Cell Ovarian Transplantation to Restore Ovarian Function in Premature Ovarian Failure [Phase 4]
This is a Phase 4 clinical trial update evaluating autologous bone marrow stem cell ovarian transplantation to restore ovarian function in w…
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Autologous Bone Marrow-Derived Stem Cell Transplantation in Patients With Premature Ovarian Failure (POF) [Phase 1, Phase 2]
This clinical trial update reports on autologous bone marrow-derived stem cell transplantation for Premature Ovarian Failure in Phase 1/Phas…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: Estrogen Treatment (Oral vs. Patches) in Turner Syndrome [Phase 3]
A Phase 3 trial comparing oral estrogen to estrogen delivered via skin patches in Turner syndrome has completed.
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CLINICAL_TRIALS withdrawal · 2017-07-02Clinical Trial Update: Effects of an Estrogen Replacement Therapy Skin Patch on Ovulation in Women With Premature Ovarian Failure [Phase 2]
Phase 2 trial evaluating a transdermal estradiol patch for ovulation induction in women with Premature ovarian failure has been withdrawn. N…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Autologous Adipose Derived Mesenchymal Stromal Cells Transplantation in Women With Premature Ovarian Failure (POF) [Phase 1, Phase 2]
Clinical trial update on autologous adipose-derived mesenchymal stromal cell transplantation for Premature Ovarian Failure (Phase 1/2); curr…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: Comparison of Transdermal and Oral Estrogens in Adolescent Girls With Ovarian Failure [NA]
A Stanford-sponsored trial compared transdermal versus oral estrogen therapy in adolescent girls with premature ovarian failure; results wer…
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CLINICAL_TRIALS research · 2016-05-02Clinical Trial Update: Oral Contraceptives as Infertility Treatments for Premature Ovarian Failure [NA]
This is a clinical trial update about using oral contraceptives as a treatment for infertility in women with primary ovarian insufficiency o…
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CLINICAL_TRIALS trial_result · 2015-02-26Clinical Trial Update: "It is a Real" The First Baby Of Autologous Stem Cell Therapy in Premature Ovarian Failure [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating autologous stem cell therapy for Premature Ovarian Failure has completed, with reports of the first ba…
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CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: X-Chromosome Inactivation Status and Premature Ovarian Failure
This trial investigated the relationship between X-chromosome inactivation status and premature ovarian failure, and the study has completed…