Prader-willi Syndrome
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Prader-Willi Syndrome Body Composition [NA]
This ClinicalTrials.gov entry reports a completed study at Taipei Tzu Chi Hospital examining body composition in Prader-Willi syndrome, incl…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Long-term Interventional Follow-up Study of Children With Prader-Willi Syndrome Included in the OTBB3 Clinical Trial [Phase 3]
A long-term interventional follow-up study of children with Prader-Willi Syndrome included in the OTBB3 Phase 3 trial is currently recruitin…
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: Open-Label Extension Study of DCCR in PWS Followed by Double-Blind, Placebo-Controlled, Randomized Withdrawal Period [Phase 3]
Phase 3 open-label extension of DCCR in Prader-Willi syndrome followed by a double-blind withdrawal period; trial completed.
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CLINICAL_TRIALS trial_result · 2024-02-26Clinical Trial Update: Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS) [Phase 2]
Phase 2 trial on co-administration of tesofensine and metoprolol in Prader-Willi syndrome has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Evaluation of Tolerance, Suckling and Food Intake After Repeated Nasals Administrations of Oxytocin in PWS Infants [Phase 1, Phase 2]
Phase 1/2 trial evaluating tolerance, suckling, and food intake after repeated nasal oxytocin in infants with Prader-Willi syndrome; study c…
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: A Study to Assess RAD011 (Cannabidiol Oral Solution) for the Treatment of Participants With Prader-Willi Syndrome [Phase 2, Phase 3]
A Phase 2/3 trial evaluating RAD011 (cannabidiol oral solution) for Prader-Willi Syndrome has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: A Study of Diazoxide Choline in Patients With Prader-Willi Syndrome [Phase 3]
Phase 3 trial of diazoxide choline in Prader-Willi Syndrome completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Cannabidiol Oral Solution for the Treatment of Patients With Prader-Willi Syndrome [Phase 2]
Phase 2 trial update for cannabidiol oral solution in Prader-Willi syndrome; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome [Phase 2]
Phase 2 trial assessing safety and efficacy of setmelanotide (RM-493) in obese participants with Prader-Willi syndrome has completed with re…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: A Study to Assess the Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Participants With Prader-Willi Syndrome [Phase 2]
Phase 2 trial assessing long-term safety of pharmaceutical grade synthetic cannabidiol oral solution in Prader-Willi syndrome was terminated…
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Effect of Intranasal Oxytocin on Dysphagia in Children and Adolescents With Prader-Willi Syndrome [Phase 2, Phase 3]
Phase 2/3 trial evaluating intranasal oxytocin for dysphagia in children and adolescents with Prader-Willi syndrome has completed.
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Oxytocin Treatment in Neonates and Infants With Prader-Willi Syndrome [Phase 3]
Phase 3 clinical trial evaluating oxytocin treatment in neonates and infants with Prader-Willi syndrome has completed.
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CLINICAL_TRIALS trial_result · 2023-03-20Clinical Trial Update: Effect of Rimonabant on Weight Gain and Body Composition in Adults With Prader Willi Syndrome [Phase 3]
Phase 3 trial assessing the effect of rimonabant on weight gain and body composition in adults with Prader-Willi syndrome was terminated.
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CLINICAL_TRIALS withdrawal · 2022-10-06Clinical Trial Update: A Phase 3 Extension Study of RAD011 (Cannabidiol Oral Solution) in Patients With Prader-Willi Syndrome [Phase 3]
Phase 3 extension study of RAD011 (cannabidiol oral solution) for Prader-Willi Syndrome has been withdrawn.
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CLINICAL_TRIALS trial_result · 2022-02-03Clinical Trial Update: Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi Syndrome [Phase 3]
Phase 3 trial evaluating liraglutide for weight management in pediatric Prader-Willi syndrome completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-11-17Clinical Trial Update: Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome [Phase 3]
Phase 3 study of intranasal carbetocin (LV-101) in Prader-Willi syndrome completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-10-07Clinical Trial Update: Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome [Phase 2]
Phase 2 trial evaluating oxytocin versus placebo for hyperphagia in children and adolescents with Prader-Willi syndrome has completed with p…
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Is There a Sensibility Increased in the Growth Hormone at Child With Prader-Willi Syndrome? [Phase 4]
Phase 4 clinical trial update assessing sensitivity to growth hormone in children with Prader-Willi Syndrome and growth hormone deficiency.
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CLINICAL_TRIALS withdrawal · 2021-08-03Clinical Trial Update: An Open-Label Study of DCCR Tablet in Patients With PWS [Phase 3]
An open-label Phase 3 study of DCCR Tablet in Prader-Willi Syndrome was withdrawn.
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CLINICAL_TRIALS trial_result · 2021-02-17Clinical Trial Update: Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome [Phase 2, Phase 3]
Phase 2/3 trial evaluating Livoletide (AZP-531) for food-related behaviors in Prader-Willi Syndrome was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: GH in Adults With PWS, Effect on Hypotonia Evaluated by Functional MRI, Relationship With Strength and Body Composition [Phase 4]
Phase 4 trial update evaluating growth hormone effects on hypotonia in adults with Prader-Willi Syndrome, by functional MRI and relation to …
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CLINICAL_TRIALS trial_result · 2021-01-11Clinical Trial Update: Weight Change in PWS Over Six Months
A completed clinical trial update reports weight change outcomes over six months in individuals with Prader-Willi syndrome.
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CLINICAL_TRIALS trial_result · 2021-01-08Clinical Trial Update: Growth Hormone Use in Adults With Prader-Willi Syndrome [Phase 3]
Phase 3 trial update on growth hormone use in adults with Prader-Willi syndrome; results posted after completion.
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CLINICAL_TRIALS withdrawal · 2020-08-26Clinical Trial Update: Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome [Phase 4]
Phase 4 clinical trial of guanfacine extended release for aggression and self-injury in Prader-Willi Syndrome was withdrawn.
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CLINICAL_TRIALS trial_result · 2020-03-27Clinical Trial Update: A Study of GLWL-01 in Patients With Prader-Willi Syndrome [Phase 2]
Phase 2 trial of GLWL-01 in Prader-Willi Syndrome completed; results posted in 2020.