Postoperative Pain
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-craniotomy Pain [Phase 4]
Phase 4 trial update on scalp infiltration with dexamethasone plus ropivacaine for post-craniotomy pain.
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Effect of Intra-Canal Cryotherapy on Postoperative Pain After Endodontic Procedures [Phase 4]
A Phase 4 clinical trial assessing whether intra-canal cryotherapy reduces postoperative pain after endodontic procedures.
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FDA approval · 2023-11-09FDA Approved: EXPAREL — Supplemental Application (Pacira Pharmaceuticals, Inc.)
FDA approved a supplemental application for EXPAREL (bupivacaine) filed by Pacira Pharmaceuticals.
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CLINICAL_TRIALS trial_result · 2023-11-08Clinical Trial Update: Multimodal Versus Opioid aNalgesia in carDiAc Surgery [Phase 4]
A Phase 4 trial comparing multimodal analgesia to opioid analgesia in cardiac surgery has completed with results posted in 2023. The study f…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Comparing Analgesic Effects of Wound Infiltration Using Bupivacaine, Tramadol, and Tramadol Plus Bupivacaine [Phase 4]
Phase 4 clinical trial update comparing analgesic effects of wound infiltration with bupivacaine, tramadol, and tramadol plus bupivacaine fo…
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp [Phase 4]
A Phase 4 clinical trial comparing Vachellia nilotica versus sodium hypochlorite as root canal irrigants for reducing postoperative pain and…
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Effects of Intrathecal Dexmedetomidine as an Adjuvant to Low Dose Hyperbaric 0.5% Bupivacaine [Phase 4]
Phase 4 clinical trial evaluating intrathecal dexmedetomidine as an adjuvant to low-dose hyperbaric bupivacaine for postoperative pain, comp…
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CLINICAL_TRIALS trial_result · 2023-10-27Clinical Trial Update: Efficacy of Rectal Sheath Analgesia After Midline Laparotomy [Phase 4]
A Phase 4 clinical trial evaluating the efficacy of rectal sheath analgesia after midline laparotomy has completed.
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: Tramadol-paracetamol Combination in Treatment of Patients Undergoing Spinal Surgery [Phase 4]
Phase 4 clinical trial update evaluating a tramadol-paracetamol combination for postoperative pain in spinal surgery patients.
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: Study of Postoperative ICC Analgesia [Phase 3]
A Phase 3 clinical trial update for a postoperative analgesia study completed by University Hospital Basel.
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: TAP Block vs Spinal Orphine for Postoperative Caesarean Section Analgetics [Phase 2]
Phase 2 trial comparing TAP block to spinal morphine for postoperative analgesia after cesarean section has completed.
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management [Phase 4]
Phase 4 trial update on bilateral continuous erector spinae blocks for post-sternotomy pain management after cardiac surgery; completed with…
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CLINICAL_TRIALS trial_result · 2023-10-16Clinical Trial Update: Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia [Phase 4]
Phase 4 clinical trial update evaluating adjuvants with intrathecal bupivacaine for postoperative analgesia.
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Evaluation of the Efficacy and Safety of HTX-011 for Postoperative Analgesia Following Abdominoplasty Surgery [Phase 2]
Phase 2 trial evaluating HTX-011 for postoperative analgesia after abdominoplasty has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Pilot Herniorrhaphy Study for Postoperative Analgesia [Phase 2]
A Phase 2 pilot study by Heron Therapeutics evaluated Zynrelef (HTX-011) for postoperative analgesia after herniorrhaphy; the trial has comp…
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy [Phase 2]
Phase 2 trial evaluating the efficacy and safety of HTX-011, a local analgesic combining bupivacaine and meloxicam, for postoperative pain r…
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Ultrasound Guided Erector Spinae Plane Block vs Intrathecal Morphine [Phase 4]
Phase 4 trial comparing ultrasound-guided erector spinae plane block with intrathecal morphine for postoperative pain demonstrates completed…
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CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone [NA]
This completed clinical trial evaluated perioperative opioid-induced hyperalgesia and whether prophylaxis with ketamine and methadone could …
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FDA approval · 2023-09-29FDA Approved: OXYCODONE AND ACETAMINOPHEN — Supplemental Application (Granules Pharmaceuticals Inc.)
FDA approved a supplemental application for Granules Pharmaceuticals Inc.'s generic oxycodone/acetaminophen product.
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CLINICAL_TRIALS withdrawal · 2023-09-26Clinical Trial Update: Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery [Phase 4]
A Phase 4 trial evaluating dexamethasone via epidural catheter as an adjunct in cesarean delivery has been withdrawn.
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: Ketamine Effects as Preemptive Analgesia [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating ketamine as preemptive analgesia for postoperative pain has completed.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Efficacy of Adding Dexmedetomidine Versus Ibuprofen as an Adjuvant to Intraperitoneal Bupivacaine for Pain Control After Laparoscopic Gynecological Procedures [Phase 2, Phase 3]
Clinical trial investigating dexmedetomidine vs ibuprofen as adjuvants to intraperitoneal bupivacaine for pain control after laparoscopic gy…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Safety and Pharmacokinetics of N1539 in Children 2 to <17 Years of Age Following Surgery [Phase 4]
Phase 4 trial evaluating safety and pharmacokinetics of N1539 in children aged 2 to under 17 years after surgery; study terminated with resu…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Continuous Nerve Block Block vs Combination of Single Block Plus Intravenous Lidocaine for Postoperative Pain. [Phase 4]
A Phase 4 trial comparing continuous nerve block to a combination of a single block plus intravenous lidocaine for postoperative pain; the s…
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CLINICAL_TRIALS trial_result · 2023-09-11Clinical Trial Update: Efficacy Side-effect Score (ESS): Development and Evaluation of a New Tool for Patients After Surgery [NA]
Clinical trial evaluating a new Efficacy Side-effect Score (ESS) tool for patients after surgery; study status completed with results posted…