Postoperative Pain
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: Transversus Abdominis Plane(TAP) Block Versus Local Anesthetic Infiltration [Phase 4]
Phase 4 clinical trial comparing TAP block to local anesthetic infiltration for postoperative pain management.
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Randomized Trial of Intraoperative IV Versus Preoperative Oral Acetaminophen During Ambulatory Lumbar Discectomy [Phase 3]
A Phase 3 randomized trial compares intraoperative IV acetaminophen to preoperative oral acetaminophen for pain management in ambulatory lum…
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Impact of Advanced Platelet Rich Fibrin and Enamel Matrix Derivative on Clinical and Molecular Wound Healing Parameters After Surgical Removal of Mandibular Third Molars [Phase 4]
Phase 4 clinical trial evaluating the impact of advanced platelet rich fibrin and enamel matrix derivative on wound healing and molecular pa…
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CLINICAL_TRIALS trial_result · 2024-01-03Clinical Trial Update: Effect of Perioperative Oral Pregabalin in Total Knee Replacement [Phase 4]
Clinical trial update on perioperative oral pregabalin for postoperative pain management in total knee replacement (Phase 4).
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CLINICAL_TRIALS trial_result · 2023-12-27Clinical Trial Update: Caudal Block With Bupivacaine and Dexmedetomidine Versus TAP Block With Bupivacaine Alone for Postoperative Analgesia in Pediatric Undergoing Infraumbical Surgeries [Phase 2]
Phase 2 clinical trial comparing caudal block with bupivacaine and dexmedetomidine versus TAP block with bupivacaine for postoperative analg…
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: Influence of Aging on Perioperative Methadone Dosing [Phase 4]
A Phase 4 trial examining how aging affects perioperative methadone dosing for postoperative pain management and opioid use.
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CLINICAL_TRIALS trial_result · 2023-12-19Clinical Trial Update: Combined Use of Naldebain® ER Injection and Precedex® After VATS [Phase 4]
Phase 4 clinical trial updating the combined use of Naldebain ER injection and Precedex following VATS for postoperative pain management and…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty [Phase 4]
Phase 4 trial comparing single-injection liposomal bupivacaine interscalene block to a continuous interscalene block for pain control after …
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FDA approval · 2023-12-15FDA Approved: DSUVIA — Supplemental Application (AcelRx Pharmaceuticals, Inc.)
FDA approved a supplemental application for DSUVIA (sufentanil) by AcelRx Pharmaceuticals, Inc., pertaining to this analgesic product.
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CLINICAL_TRIALS trial_result · 2023-12-15Clinical Trial Update: Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures [Phase 4]
Phase 4 clinical trial evaluating multimodal periarticular injections for pain management after operative treatment of ankle fractures; resu…
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FDA approval · 2023-12-15FDA Approved: MEPERIDINE HYDROCHLORIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approves Hikma Pharmaceuticals USA Inc.’s supplemental application for Meperidine Hydrochloride, approving a generic version of this opi…
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FDA approval · 2023-12-14FDA Approved: HYDROMORPHONE HYDROCHLORIDE — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved hydromorphone hydrochloride from Hikma Pharmaceuticals USA Inc. under Original Application NDA217812 for pain management.
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Use of Corticosteroids in Third Molar Surgery [Phase 2, Phase 3]
Phase 2/3 clinical trial assessing corticosteroids for inflammation and pain management after third molar surgery has been completed.
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CLINICAL_TRIALS trial_result · 2023-12-05Clinical Trial Update: Intraoperative Methadone for Postoperative Pain in Patients Undergoing Tonsillectomy [Phase 4]
A Phase 4 clinical trial evaluating intraoperative methadone for postoperative pain in tonsillectomy patients; current status is unknown.
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CLINICAL_TRIALS trial_result · 2023-12-01Clinical Trial Update: Effectiveness of Adductor Canal Block Using Liposomal Bupivacaine [Phase 4]
Phase 4 trial update evaluating the effectiveness of adductor canal block with liposomal bupivacaine for postoperative pain.
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FDA approval · 2023-11-28FDA Approved: EXPAREL — Supplemental Application (Pacira Pharmaceuticals, Inc.)
The FDA approved a supplemental application for EXPAREL (bupivacaine) from Pacira Pharmaceuticals, Inc. This action approves changes to the …
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Effect of Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Ankle Surgery [Phase 4]
Phase 4 clinical trial assessing whether perineural dexamethasone extends the duration of the popliteal nerve block after ankle surgery.
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Magnesium Sulphate in Oblique Subcostal TAP Block [Phase 2, Phase 3]
A clinical trial update regarding magnesium sulfate in oblique subcostal TAP block across Phase 2 and Phase 3 for postoperative pain managem…
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Postoperative Analgesia After Minithoracotomy [Phase 4]
A Phase 4 clinical trial update on postoperative analgesia following minithoracotomy for mitral valve disease has completed.
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Bupivacaine Versus Lidocaine Infiltration for Postoperative Pain in Thyroid Surgery [Phase 2]
A Phase 2 clinical trial comparing bupivacaine vs lidocaine infiltration for postoperative pain relief after thyroid surgery.
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CLINICAL_TRIALS trial_result · 2023-11-27Clinical Trial Update: Virtual Reality Distraction for Reduction [NA]
Clinical trial assessing virtual reality distraction for postoperative pain reduction has completed and posted results.
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: A COMPARISON OF TRANSDERMAL DICLOFENAC AND ORAL COMBINATION OF PARACETAMOL AND IBUPROFEN IN POSTOPERATIVE PAIN MANAGEMENT FOLLOWING SURGICAL EXTRACTION OF MANDIBULAR THIRD MOLAR- A RANDOMISD CONTROLLED TRIALS. [Phase 4]
A Phase 4 randomized trial comparing transdermal diclofenac to an oral paracetamol+ibuprofen combination for postoperative pain after surgic…
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: TAP vs QLB in Patients After Cesarean Delivery [Phase 4]
Phase 4 trial update comparing TAP block vs QLB for postoperative pain after cesarean delivery has completed.
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: THRIVE Feasibility Trial [Phase 3]
A Phase 3 feasibility trial called THRIVE completed, investigating surgical and anesthesia-related outcomes.
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EMA withdrawal · 2023-11-22EMA Withdrawn: Zynrelef (bupivacaine;meloxicam) — Heron Therapeutics, B.V.
The EMA has withdrawn Zynrelef, a bupivacaine/meloxicam combination, from the market for postoperative pain management.