Postoperative Pain
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2026-04-03Clinical Trial Update: Vaginal Cuff Infiltration With Liposomal Bupivacaine for Pain Relief: A Double Blind, Randomized Controlled Trial [Phase 4]
A Phase 4 randomized, double-blind trial evaluating vaginal cuff infiltration with liposomal bupivacaine for postoperative pain relief has b…
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CLINICAL_TRIALS withdrawal · 2026-03-03Clinical Trial Update: Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation [NA]
The clinical trial evaluating auricular acupuncture as part of a multimodal regimen after distal radius open reduction and internal fixation…
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CLINICAL_TRIALS withdrawal · 2026-02-05Clinical Trial Update: The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty [Phase 4]
A Phase 4 clinical trial evaluating a methylprednisolone taper to improve outcomes after total knee arthroplasty has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2026-01-15Clinical Trial Update: Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients [Phase 4]
A Phase 4 study evaluating micro-dosing buprenorphine/naloxone for postoperative pain management in opioid-tolerant patients has been withdr…
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CLINICAL_TRIALS withdrawal · 2025-11-26Clinical Trial Update: Parasternal Subpectoral Plane Blocks for Cardiac Surgery Via a Midline Sternotomy [NA]
Clinical trial investigating parasternal subpectoral plane blocks for cardiac surgery via midline sternotomy; the study has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-09-11Clinical Trial Update: Psychological and Social Factors and Risk Chronic Pain After Surgery in Women With Breast Cancer
A clinical trial examining psychosocial factors and the risk of chronic postoperative pain after breast cancer surgery has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-08-11Clinical Trial Update: Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom Limb Pain [NA]
This clinical trial evaluating preoperative cryoanalgesia to reduce phantom limb pain after amputation has been withdrawn from ClinicalTrial…
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CLINICAL_TRIALS withdrawal · 2025-06-15Clinical Trial Update: Pain Profile and Pain Medication Use After THA and TKA
The clinical trial NCT03714711 assessing postoperative pain and pain medication use after total hip and total knee arthroplasty has been wit…
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CLINICAL_TRIALS withdrawal · 2025-04-11Clinical Trial Update: Beneficial Side Effects of Topiramate in Obese Patients Undergoing Total Joint Arthroplasty [EARLY_Phase 1]
A Phase 1 clinical trial evaluating topiramate for weight loss in obese patients undergoing total joint arthroplasty has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-02-17Clinical Trial Update: Continuous Erector Spinae Block Versus Continuous Paravertebral Block [Phase 3]
A Phase 3 trial comparing continuous erector spinae block with continuous paravertebral block for postoperative pain has been terminated.
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CLINICAL_TRIALS withdrawal · 2025-02-03Clinical Trial Update: Management of Postoperative Pain After Cesarean Delivery Using Bridge Auricular Percutaneous Nerve Field Stimulator [NA]
The clinical trial assessing Bridge Auricular Percutaneous Nerve Field Stimulator for managing acute postoperative pain after cesarean deliv…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD [NA]
Clinical trial comparing propofol and dexmedetomidine versus midazolam for intraoperative sedation and postoperative cognitive dysfunction; …
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section. [Phase 4]
Phase 4 trial comparing intrathecal morphine alone to intrathecal morphine with regional anesthesia for cesarean-section analgesia has been …
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CLINICAL_TRIALS withdrawal · 2024-07-08Clinical Trial Update: Efficacy of Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy [Phase 3]
A Phase 3 trial evaluating transversus abdominis plane block for postoperative pain control after laparoscopic cholecystectomy has been with…
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CLINICAL_TRIALS withdrawal · 2024-04-10Clinical Trial Update: Liposomal Bupivacaine + Bupivacaine vs. Bupivacaine Alone on Opioid Use After Elective c/Section [Phase 4]
A Phase 4 trial comparing liposomal bupivacaine plus bupivacaine to bupivacaine alone for postoperative opioid use after cesarean section ha…
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EMA withdrawal · 2023-11-22EMA Withdrawn: Zynrelef (bupivacaine;meloxicam) — Heron Therapeutics, B.V.
The EMA has withdrawn Zynrelef, a bupivacaine/meloxicam combination, from the market for postoperative pain management.
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CLINICAL_TRIALS withdrawal · 2023-09-26Clinical Trial Update: Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery [Phase 4]
A Phase 4 trial evaluating dexamethasone via epidural catheter as an adjunct in cesarean delivery has been withdrawn.
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EMA withdrawal · 2022-09-27EMA Withdrawn: Zalviso (sufentanil) — FGK Representative Service GmbH
Zalviso (sufentanil) has been withdrawn from the European market per EMA decision in 2022.
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CLINICAL_TRIALS withdrawal · 2022-06-03Clinical Trial Update: Pericapsular Nerve Group Block (PENG) for Hip Surgery [Phase 4]
Phase 4 trial of Pericapsular Nerve Group (PENG) block for hip surgery was withdrawn.
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CLINICAL_TRIALS withdrawal · 2022-05-31Clinical Trial Update: Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low Transverse (Pfannenstiel) Incision [Phase 4]
A Phase 4 trial evaluating continuous erector spinae plane blocks for postoperative pain after open gynecologic surgery with Pfannenstiel in…
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CLINICAL_TRIALS withdrawal · 2021-10-29Clinical Trial Update: Post Operative Pain Control for Distal Radius Surgery: Does Exparel Injected at the Surgery Site Improve Postoperative Pain Scores at 24 and 48 Hours ? [Phase 4]
A Phase 4 trial evaluating Exparel for postoperative pain after distal radius surgery was withdrawn.
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CLINICAL_TRIALS withdrawal · 2021-05-25Clinical Trial Update: Combination of Preoperative Gabapentin and TAP Blocks in Decreasing Postoperative Pain [Phase 4]
A Phase 4 trial evaluating preoperative gabapentin with TAP blocks to reduce postoperative pain was withdrawn.
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CLINICAL_TRIALS withdrawal · 2021-02-16Clinical Trial Update: Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies [Phase 4]
Phase 4 clinical trial comparing different quadratus lumborum block strategies in nephrectomies has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-07-31Clinical Trial Update: Liposomal Bupivacaine After Cesarean Delivery [Phase 4]
Phase 4 trial of liposomal bupivacaine after cesarean delivery was withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-07-15Clinical Trial Update: Comparison of Exparel to Marcaine in Post-Surgical Analgesia in Bariatrics [Phase 4]
Clinical trial comparing Exparel to Marcaine for post-surgical analgesia in bariatric patients was withdrawn (Phase 4).