Postoperative Cognitive Dysfunction
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study [Phase 2]
Phase 2 study evaluating caffeine to prevent or reduce postoperative delirium and postoperative cognitive dysfunction after surgery; status …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Post Operative Cognitive Dysfunction After Breast Surgery
A University of Padova-sponsored clinical trial studying postoperative cognitive dysfunction after breast surgery is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients [Phase 4]
Phase 4 trial evaluating esketamine for preventing delayed neurocognitive recovery in elderly patients after noncardiac surgery. The study f…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Depth of Anaesthesia and Long-term Survival: The Balanced Anaesthesia Follow-up Study
This clinical trial update describes a follow-up study evaluating whether depth of anesthesia during surgery is associated with long-term ou…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Value of the Time-Weighted Average (TWA) of Mean Arterial Pressure (MAP) and Cerebral Oximetry (rSO₂) as Predictors of Postoperative Tissue Perfusion Impairment in Patients Undergoing Cardiac Surgery
A clinical trial evaluating whether time-weighted MAP and cerebral oximetry predict postoperative tissue perfusion impairment in patients un…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Effect of Low Tidal Volume Ventilation on Postoperative Delirium [NA]
A completed clinical trial investigated whether low tidal volume ventilation influences the development of postoperative delirium in patient…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Prediction Model for Postoperative Cognitive Dysfunction in Elderly Cardiac Patients: A Special Disease Cohort Study
A clinical trial update about a study aimed at predicting postoperative cognitive dysfunction in elderly patients undergoing cardiac surgery…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Venous Congestion And Cognitive Dysfunction After Cardiac Surgery
A recruiting clinical trial investigating intraoperative venous congestion and postoperative cognitive dysfunction following cardiac surgery…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Anesthesia Maintenance With Target-controlled Infusion of Propofol and Remifentanil at Fixed Ratio [Phase 4]
Phase 4 clinical trial from Peking University First Hospital evaluating anesthesia maintenance using a fixed-ratio target-controlled infusio…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Optic Nerve Sheath Diameter and Cognitive Outcomes in Bentall Surgery
Clinical trial evaluating whether optic nerve sheath diameter predicts cognitive outcomes after Bentall surgery. It is currently recruiting …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass
A clinical trial is investigating whether Transcranial Doppler can predict postoperative cognitive dysfunction and postoperative delirium af…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients [NA]
This clinical trial is evaluating whether increasing preoperative cognitive reserve can prevent postoperative cognitive dysfunction and deli…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients. [NA]
An ongoing clinical trial in Germany is exploring whether reducing preoperative stress can prevent postoperative delirium and postoperative …
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Effect of Perioperative IV Ibuprofen on Cerebral Oxygenation and Postoperative Cognition During One-Lung Ventilation [NA]
This clinical trial will evaluate whether perioperative intravenous ibuprofen affects cerebral oxygenation and postoperative cognitive outco…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Postoperative Cognitive Dysfunction in Elderly and it's Relation With Sleep Disorders and Melanin Concentrating Hormone
A clinical trial from Minia University is investigating postoperative cognitive dysfunction in elderly patients and its relation to sleep di…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Audio-Recorded Messages Delivered Via iPad to Prevent Delirium in Hip Fracture Patients [NA]
This clinical trial evaluates whether audio-recorded messages delivered via an iPad can prevent delirium in hip fracture patients after surg…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery
A clinical trial from University Hospital Basel is evaluating personalized cardiac anesthesia and cerebral autoregulation to improve neurolo…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Target-Controlled Infusion and Postoperative Neurocognitive Outcomes in Geriatric Patients
A completed clinical trial evaluating target-controlled infusion and its effect on postoperative neurocognitive outcomes in elderly patients…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: "Effects of Fluid Status and Regional Cerebral Oxygenation on Postoperative Cognitive Dysfunction in Patients Undergoing Lower Extremity Surgery Under General and Spinal Anesthesia."
This clinical trial update describes an ongoing study looking at how fluid status and regional cerebral oxygenation may affect postoperative…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Impact of Combined PSi + NIRS Monitoring in the Prevention of Postoperative Cognitive Disorders in Cardiac Surgery. [NA]
A clinical trial evaluating whether combined PSi and NIRS monitoring during cardiac surgery can prevent postoperative cognitive disorders; c…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients [Phase 4]
Phase 4 clinical trial update on cognitive outcomes after dexmedetomidine sedation in adults undergoing cardiac surgery; currently recruitin…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Retrospective Evaluation of POCD Data of Studies From KAI, Charité - Universitätsmedizin Berlin
A retrospective evaluation of postoperative cognitive dysfunction (POCD) data from studies at Charité – Universitätsmedizin Berlin is curren…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State
A clinical trial update states that CEReBral AutorEgulation in non-cardiac surgery is currently recruiting to study its relationship with po…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Perioperative GDNF as a Predictive Factor for Postoperative Delirium and Adverse Neurological Outcomes in Pediatric Surgery [NA]
A pediatric perioperative trial is investigating whether perioperative GDNF levels can serve as a predictive biomarker for postoperative del…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: WashIn /WashOut Procedure To Prevent Agitation During Recovery After Inhalational Anesthesia With Sevoflurane [NA]
Clinical trial evaluating a wash-in/wash-out procedure to reduce agitation, emergence delirium, and postoperative cognitive dysfunction afte…