Postoperative Cognitive Dysfunction
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study [Phase 2]
Phase 2 study evaluating caffeine to prevent or reduce postoperative delirium and postoperative cognitive dysfunction after surgery; status …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Post Operative Cognitive Dysfunction After Breast Surgery
A University of Padova-sponsored clinical trial studying postoperative cognitive dysfunction after breast surgery is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients [Phase 4]
Phase 4 trial evaluating esketamine for preventing delayed neurocognitive recovery in elderly patients after noncardiac surgery. The study f…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: GDFT and Postoperative Cognitive Function in Geriatric Cancer Surgery
The study investigates goal-directed fluid therapy (GDFT) and its effect on postoperative cognitive function in elderly patients undergoing …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Depth of Anaesthesia and Long-term Survival: The Balanced Anaesthesia Follow-up Study
This clinical trial update describes a follow-up study evaluating whether depth of anesthesia during surgery is associated with long-term ou…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium
A completed clinical trial evaluated whether serum S100B levels and S100B gene polymorphisms predict postoperative cognitive dysfunction and…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Value of the Time-Weighted Average (TWA) of Mean Arterial Pressure (MAP) and Cerebral Oximetry (rSO₂) as Predictors of Postoperative Tissue Perfusion Impairment in Patients Undergoing Cardiac Surgery
A clinical trial evaluating whether time-weighted MAP and cerebral oximetry predict postoperative tissue perfusion impairment in patients un…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Effect of Low Tidal Volume Ventilation on Postoperative Delirium [NA]
A completed clinical trial investigated whether low tidal volume ventilation influences the development of postoperative delirium in patient…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Prediction Model for Postoperative Cognitive Dysfunction in Elderly Cardiac Patients: A Special Disease Cohort Study
A clinical trial update about a study aimed at predicting postoperative cognitive dysfunction in elderly patients undergoing cardiac surgery…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Venous Congestion And Cognitive Dysfunction After Cardiac Surgery
A recruiting clinical trial investigating intraoperative venous congestion and postoperative cognitive dysfunction following cardiac surgery…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Anesthesia Maintenance With Target-controlled Infusion of Propofol and Remifentanil at Fixed Ratio [Phase 4]
Phase 4 clinical trial from Peking University First Hospital evaluating anesthesia maintenance using a fixed-ratio target-controlled infusio…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Minimal-flow Anesthesia and Cognitive Outcomes in Elderly Surgical Patients [NA]
A clinical trial evaluating minimal-flow anesthesia and its impact on postoperative cognitive dysfunction in elderly surgical patients has c…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: EEG-based Depth of Anesthesia-monitoring, Effects on Dosage and Cognition [NA]
A completed clinical trial evaluating EEG-based depth of anesthesia monitoring and its impact on anesthetic dosing and postoperative cogniti…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery [NA]
This clinical trial update notes the completion of a study assessing whether dexmedetomidine affects postoperative cognitive function in pat…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: The Effect of Intravenous Versus Volatile Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients [NA]
The clinical trial comparing intravenous versus volatile anesthesia for postoperative cognitive dysfunction in elderly patients has complete…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Impact of Obesity on Post-operative Cognitive Dysfunction: Role of Adipose Tissue
A completed clinical trial from University Hospital, Toulouse examined the impact of obesity and adipose tissue on postoperative cognitive d…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Investigation of the Effect of Preoperative Bowel Cleansing on Postoperative Cognitive Impairment [NA]
A completed clinical trial from Erciyes University evaluated whether preoperative bowel cleansing influences postoperative cognitive impairm…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Optic Nerve Sheath Diameter and Cognitive Outcomes in Bentall Surgery
Clinical trial evaluating whether optic nerve sheath diameter predicts cognitive outcomes after Bentall surgery. It is currently recruiting …
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Effect of Targeted Fluid Therapy on Postoperative Cognitive Dysfunction. [NA]
This entry notes a completed clinical trial assessing targeted fluid therapy for postoperative cognitive dysfunction.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass
A clinical trial is investigating whether Transcranial Doppler can predict postoperative cognitive dysfunction and postoperative delirium af…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients [NA]
This clinical trial is evaluating whether increasing preoperative cognitive reserve can prevent postoperative cognitive dysfunction and deli…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients. [NA]
An ongoing clinical trial in Germany is exploring whether reducing preoperative stress can prevent postoperative delirium and postoperative …
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Effect of Perioperative IV Ibuprofen on Cerebral Oxygenation and Postoperative Cognition During One-Lung Ventilation [NA]
This clinical trial will evaluate whether perioperative intravenous ibuprofen affects cerebral oxygenation and postoperative cognitive outco…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Postoperative Cognitive Dysfunction in Elderly and it's Relation With Sleep Disorders and Melanin Concentrating Hormone
A clinical trial from Minia University is investigating postoperative cognitive dysfunction in elderly patients and its relation to sleep di…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Audio-Recorded Messages Delivered Via iPad to Prevent Delirium in Hip Fracture Patients [NA]
This clinical trial evaluates whether audio-recorded messages delivered via an iPad can prevent delirium in hip fracture patients after surg…