Post-traumatic Osteoarthritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-06Clinical Trial Results: Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA [Phase 1, Phase 2]
Phase 1/2 clinical trial that investigated metabolic responses and early interventions to prevent post-traumatic osteoarthritis; the study s…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA [NA]
The trial update reports a completed study evaluating an imaging framework to clinically test new treatments aimed at preventing post-trauma…
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CLINICAL_TRIALS withdrawal · 2026-02-27Clinical Trial Update: Stromal Vascular Fraction (SVF) for Knee Post-Trauma Osteoarthritis (PTOA) [EARLY_Phase 1]
The EARLY Phase 1 trial evaluating Stromal Vascular Fraction for knee post-trauma osteoarthritis has been withdrawn.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: PRP in ACLR to Prevent PTOA [Phase 3]
A Phase 3 clinical trial is evaluating platelet-rich plasma (PRP) in anterior cruciate ligament reconstruction to prevent post-traumatic ost…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: UK Infinity, Post-Market Clinical Follow-up Study
This is a post-market clinical follow-up study of the Stryker UK Infinity device. It monitors long-term safety and performance in arthritis-…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics [NA]
A completed clinical trial evaluated carbon fiber orthosis cuff designs for preference, comfort, and mechanics. The study enrolled healthy v…
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CLINICAL_TRIALS withdrawal · 2026-01-15Clinical Trial Update: Custom Dynamic Orthoses to Reduce Articular Contact Stress [NA]
A University of Iowa-sponsored trial evaluating custom dynamic orthoses to reduce articular contact stress in ankle fractures and post-traum…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Exactech Shoulder Post Market Clinical Follow-up Study
Exactech is conducting a post-market clinical follow-up study for shoulder implants, and participant recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Randomized Comparison of PARtial Wrist Fusion With or Without Triquetral Excision (PARTE) [NA]
A randomized trial compares partial wrist fusion with versus without triquetral excision (PARTE) for various wrist conditions, and the study…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Efficacy of an Evidence-based Telehealth Intervention in Modifying Health Behavior [NA]
A clinical trial is ongoing but not currently recruiting, evaluating a telehealth program designed to modify health behaviors in people with…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Long Term Follow-up of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement
Long-term follow-up data for the Integra Cadence Total Ankle System in primary ankle joint replacement is provided, with the study status li…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Inflammatory Response Following Intraarticular Fracture
An update on a University of Utah clinical trial investigating the inflammatory response after intraarticular fractures; the study is curren…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Gait Rehabilitation to Treat FastOA [NA]
This ClinicalTrials.gov entry shows a gait rehabilitation study for fast osteoarthritis (FastOA) that is currently recruiting, sponsored by …
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Avenir Complete Post-Market Clinical Follow-Up Study [NA]
Zimmer Biomet's Avenir Complete post-market clinical follow-up study is active but not recruiting, monitoring patients with hip osteoarthrit…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: PMCF Study on the Safety and Performance of the Zimmer® Maxera™ Acetabular System in Total Hip Arthroplasty
This entry describes a post-market clinical follow-up (PMCF) study evaluating the safety and performance of the Zimmer Maxera Acetabular Sys…
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CLINICAL_TRIALS other · 2025-06-04Clinical Trial Update: Insignia™ Hip Stem Outcomes Study [NA]
This document provides a status update on the Insignia Hip Stem Outcomes Study (NCT05144191) sponsored by Stryker Orthopaedics. The trial is…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury [NA]
A UNC-Chapel Hill-led clinical trial is recruiting to evaluate whether vibration therapy affects the risk of post-traumatic osteoarthritis a…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: STABILITY: Physical Activity Intervention at 7 Years Post-Anterior Cruciate Ligament Reconstruction [NA]
This update reports that the STABILITY trial evaluating a physical activity intervention seven years after anterior cruciate ligament recons…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Mirror Medacta Shoulder System Pivotal Trial [NA]
An update on the pivotal Mirror Medacta Shoulder System trial indicates the study is currently recruiting for its indicated shoulder conditi…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial) [EARLY_Phase 1]
Early-phase clinical trial evaluating montelukast as a potential chondroprotective treatment after ACL reconstruction; currently recruiting.
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Preventing Injured Knees From osteoArthritis: Severity Outcomes [Phase 2]
Phase 2 clinical trial at Brigham and Women's Hospital aims to prevent progression of knee osteoarthritis after injury. The trial's conditio…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Prevention of Post mEniscectomy Osteoarthritis: From New Animal Model to Patient pRofiLing
Clinical trial aiming to prevent osteoarthritis after meniscectomy, progressing from an animal model to patient profiling and currently enro…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Exercise Loading Biology Post-Traumatic OsteoArthritis Study - a Pilot and Feasibility Study
A pilot and feasibility study evaluating exercise loading biology in post-traumatic osteoarthritis following ACL injury; currently enrolling…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: SMR Stemless Shoulder Arthroplasty Clinical Study [NA]
A completed clinical study of the SMR Stemless Shoulder Arthroplasty sponsored by Limacorporate S.p.a. evaluating outcomes in shoulder osteo…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress [NA]
A completed clinical trial from the University of Iowa evaluating custom dynamic ankle orthoses to reduce articular contact stress in ankle …