Post-polycythemia Vera Myelofibrosis
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis [Phase 2]
This update describes a Phase 2 study evaluating momelotinib in combination with luspatercept for transfusion-dependent myelofibrosis; the t…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF) [Phase 3]
This Phase 3 trial evaluates pelabresib in combination with ruxolitinib for myelofibrosis and is currently recruiting across primary MF and …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017) [Phase 3]
Phase 3 study of bomedemstat (MK-3543-017) sponsored by Merck is currently recruiting to evaluate safety and efficacy in essential thrombocy…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With Myelofibrosis [Phase 1]
Phase 1 study evaluating pelabresib added to ruxolitinib in Japanese adults with myelofibrosis (primary, post-polycythemia vera, or post-ess…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Registry Platform Myelofibrosis and Anemia
A ClinicalTrials.gov registry entry for a recruiting trial by iOMEDICO AG focused on myelofibrosis and anemia. It lists several MF-related c…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i) [Phase 1]
Phase 1 study of AJ1-11095 in patients with primary myelofibrosis and post-polycythemia vera or post-essential thrombocythemia myelofibrosis…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Selinexor and Pacritinib in JAK Inhibitor-naïve MF Patients With Cytopenias [Phase 2]
This clinical trial update announces a Phase 2 study evaluating selinexor and pacritinib in JAK inhibitor‑naïve myelofibrosis patients with …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Open Label Phase 1/2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF) [Phase 1, Phase 2]
An open-label Phase 1/2 study evaluating tasquinimod in primary myelofibrosis and myelofibrosis following PV or essential thrombocythemia is…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Elotuzumab for the Treatment of JAK2-Mutated Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating elotuzumab for JAK2-mutated myelofibrosis; the study is active but not recruiting and includes myelofibros…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib [Phase 3]
Phase 3 trial evaluating navtemadlin added to ruxolitinib in JAK inhibitor-naïve myelofibrosis patients with suboptimal response; currently …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions [Phase 3]
This Phase 3 trial compares luspatercept against placebo in patients with myeloproliferative neoplasm-associated myelofibrosis who are on JA…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Ropeginterferon Alfa 2b Plus Ruxolitinib for Myelofibrosis [Phase 2]
A Phase 2 clinical trial evaluating a combination of Ropeginterferon alfa-2b and ruxolitinib for myelofibrosis is currently recruiting, incl…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: A Phase II Clinical Trial of Flonoltinib Maleate Tablet in Intermediate-High Risk Myelofibrosis [Phase 2]
Phase II trial update for Flonoltinib maleate tablets in intermediate-high-risk myelofibrosis; the study is currently recruiting.
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: A Post-Marketing Surveillance Study to Assess the Safety of Fedratinib in Korean Patients With Myelofibrosis
A post-marketing surveillance study to assess the safety of fedratinib in Korean patients with myelofibrosis, currently recruiting.
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CLINICAL_TRIALS research · 2024-05-03Clinical Trial Update: Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition [Phase 1]
A Phase 1 clinical trial at Fox Chase Cancer Center tests the combination of pacritinib and talazoparib in myeloproliferative neoplasms unre…