Poorly Differentiated Thyroid Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial [Phase 1]
Phase 1 feasibility trial evaluating repurposed drugs for thyroid carcinoma; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Sacituzumab Tirumotecan Combined With Immunotherapy in Advanced Thyroid Cancer [NA]
A clinical trial update indicates recruitment for a study of Sacituzumab Govitecan in combination with immunotherapy for advanced thyroid ca…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Lenvatinib and Pembrolizumab for the Treatment of Stage IVB Locally Advanced and Unresectable or Stage IVC Metastatic Anaplastic Thyroid Cancer [Phase 2]
A Phase 2 clinical trial update for lenvatinib plus pembrolizumab in stage IVB unresectable or stage IVC metastatic anaplastic thyroid cance…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: [177Lu]Lu-AKIR001 First-in-human Study [EARLY_Phase 1]
First-in-human early-phase trial of a Lu-177 radiopharmaceutical, [177Lu]Lu-AKIR001, currently recruiting for various advanced cancers.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Atezolizumab With Chemotherapy in Treating Patients With Anaplastic or Poorly Differentiated Thyroid Cancer [Phase 2]
Phase 2 trial evaluating atezolizumab with chemotherapy for anaplastic and poorly differentiated thyroid carcinoma; the study is active but …
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: MRG003 and Pucotenlimab to Treat Locally Advanced or Metastatic ATC/PDTC [Phase 2]
Phase 2 clinical trial evaluating MRG003 in combination with pucotenlimab for anaplastic thyroid carcinoma and poorly differentiated thyroid…
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer [Phase 2]
Phase 2 clinical trial evaluating selpercatinib given before surgery for RET-altered thyroid cancers is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Testing the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer [Phase 2]
Phase 2 trial update reports results from CaboNivoIpi (cabozantinib, nivolumab, ipilimumab) in advanced differentiated thyroid cancer, inclu…
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer [Phase 2]
Phase 2 clinical trial evaluating PDR001 in combination therapy for radioiodine-refractory thyroid cancer is active but not recruiting.
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Phase II Trial of Tunlametinib in NRAS-Mutant Advanced Thyroid Cancer [Phase 2]
Phase II trial of tunlametinib in NRAS-mutant advanced thyroid cancer is currently recruiting, evaluating differentiated, poorly differentia…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer [Phase 2]
Phase 2 clinical trial update indicating that XL092 for locally advanced or metastatic radioiodine-refractory differentiated thyroid cancer …
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: Lenvatinib and Pembrolizumab in Differentiated Thyroid Cancers (DTC) [Phase 2]
A Phase 2 trial evaluating the combination of lenvatinib and pembrolizumab in differentiated thyroid cancers has completed, with results pos…
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CLINICAL_TRIALS trial_result · 2022-12-28Clinical Trial Update: Trametinib in Increasing Tumoral Iodine Incorporation in Patients With Recurrent or Metastatic Thyroid Cancer [Phase 2]
Phase 2 trial evaluating trametinib for increasing tumoral iodine incorporation in patients with recurrent or metastatic thyroid cancer; res…
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CLINICAL_TRIALS trial_result · 2021-08-03Clinical Trial Update: Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer [Phase 2]
Phase 2 trial evaluating whether adding selumetinib to radioactive iodine improves outcomes in patients with recurrent or metastatic thyroid…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer [Phase 2]
Phase 2 trial of cabozantinib-s-malate in patients with refractory thyroid cancer has been completed, with results posted in 2018. The study…
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: PLD Combined With Cisplatin in the Treatment of Advanced Poorly Differentiated Thyroid Carcinoma [Phase 2]
Phase 2 trial evaluating the combination of pegylated liposomal doxorubicin (PLD) with cisplatin for advanced poorly differentiated thyroid …
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CLINICAL_TRIALS trial_result · 2014-01-17Clinical Trial Update: A Pilot Clinical Trial for Poorly Differentiated Thyroid Cancer - Correlation to Retinoid and Peroxisome-proliferator-activated Receptor (PPARy) Expression [EARLY_Phase 1]
This early Phase 1 pilot trial in poorly differentiated thyroid cancer evaluated correlations with retinoid and PPAR gamma expression; resul…