Polyneuropathy
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Accuracy of the Polymerase Chain Reaction of Ulnar Perineural Subcutaneous Aspirate Guided by Ultrasound for the Diagnosis and Monitoring of Leprosy Cure [NA]
This clinical trial update reports on evaluating the accuracy of ultrasound-guided PCR of ulnar perineural aspirates for diagnosing and moni…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia
This document reports the completion of a clinical trial investigating hereditary transthyretin amyloidosis with polyneuropathy in patients …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant [Phase 3]
This entry notes that Acoramidis is being evaluated in a Phase 3 ACT-EARLY prevention trial in asymptomatic carriers of pathogenic TTR varia…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: ChatGPT in the Diagnosis and Management of Complex Polyneuropathies: Comparative Analysis With Neurologists Using Real-World Cases
A completed study evaluated how well ChatGPT can assist in diagnosing and managing complex polyneuropathies. The analysis compared its perfo…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Turkish Validation and Reliability of the John Hopkins In-Room Independence Scale
Turkish validation and reliability assessment of the John Hopkins In-Room Independence Scale, a tool for measuring functional independence i…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Effect of Exercise and Surgical Weight Loss on Polyneuropathy [NA]
This completed clinical trial evaluated the impact of exercise and surgical weight loss on polyneuropathy in individuals with obesity, with …
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Individual Patient Expanded Access IND to Treat Polyneuropathy
An update indicates that an individual patient expanded access IND for polyneuropathy is no longer available.
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease) [NA]
A clinical trial investigating the effects of resistance exercises in Charcot-Marie-Tooth disease is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Ultrasound Evaluation of Hematoma Risk After Needle EMG in Patient on DOAC Therapy
A Masaryk University-sponsored trial is evaluating ultrasound-detected hematoma risk after needle EMG in patients taking direct-acting antic…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause. [NA]
A clinical trial evaluating how prevalent wild-type transthyretin cardiac amyloidosis is among patients with polyneuropathy of unknown cause…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects
This clinical trial update describes the TRAMmoniTTR study, a genetic screening program for individuals at risk of hereditary transthyretin …
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: A New Cancer Rehabilitation Process for Chemotherapy-Induced Foot Neuropathy Using Orthopedic Devices [NA]
A clinical trial is testing a novel rehabilitation method using orthopedic devices to treat chemotherapy-induced foot neuropathy in breast c…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System
Enrollment by invitation is ongoing for a prodromal Parkinson's disease model confined to the peripheral nervous system.
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Assessment of Effectiveness and Stimulation Coverage of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Patients with Cervical Lead Placement
A clinical trial evaluating the effectiveness and stimulation coverage of closed-loop spinal cord stimulation (CL-SCS) in patients with cerv…
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.
This is a completed retrospective study collecting neurological follow-up data from hereditary transthyretin amyloidosis (ATTRv) patients en…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Ultrasonography in Diagnosis of Polyneuropathy
Clinical trial evaluating ultrasonography as a diagnostic tool for polyneuropathy. The study status is not yet recruiting.
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CLINICAL_TRIALS withdrawal · 2018-05-31Clinical Trial Update: Neuromuscular Electrical Stimulation in the Critically Ill [NA]
A clinical trial evaluating neuromuscular electrical stimulation for polyneuropathy has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-04-18Clinical Trial Update: Trial of Quercetin in the Treatment and Prevention of Chemotherapy-induced Neuropathic Pain in Cancer Patients [EARLY_Phase 1]
An early-phase trial investigating quercetin for chemotherapy-induced peripheral neuropathy in cancer patients has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Rituximab to Treat Neuropathy With Anti-MAG Antibodies [Phase 2]
A Phase 2 clinical trial evaluating rituximab for anti-MAG antibody-associated polyneuropathy has completed.
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Evaluate The Efficacy and Safety Of Pregabalin In Prevention, Reduction of Oxaliplatin-Induced Painful Neuropathy [Phase 3]
A Phase 3 clinical trial evaluated pregabalin for the prevention and reduction of oxaliplatin-induced painful peripheral neuropathy; the stu…
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: The Influence of Sensory Phenotype on the Risk of Developing Neuropathic Pain
This update reports on a University of Kiel clinical study investigating how sensory phenotype affects the risk of developing neuropathic pa…
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CLINICAL_TRIALS trial_result · 2015-04-10Clinical Trial Update: Neurogenic Inflammation in Diabetes [NA]
The trial NCT01370837, investigating neurogenic inflammation in diabetes, has completed and posted results in 2015.
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CLINICAL_TRIALS trial_result · 2014-06-30Clinical Trial Update: Study of Ranexa in Patients With Coronary Artery Disease and Painful Polyneuropathy [Phase 4]
A Phase 4 study of ranolazine (Ranexa) in patients with coronary artery disease and painful polyneuropathy was terminated, with results post…
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CLINICAL_TRIALS trial_result · 2014-05-05Clinical Trial Update: Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Pain [Phase 4]
Phase 4 clinical trial update shows completion of oxcarbazepine for chronic peripheral neuropathic pain, including polyneuropathy, periphera…
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CLINICAL_TRIALS research · 2014-04-28Clinical Trial Update: National Registry for Egyptian Pediatric Neuromuscular Diseases
This document provides an update on Egypt's National Registry for Pediatric Neuromuscular Diseases, cataloging Spinal Muscular Atrophy, Musc…