Plasmodium Vivax Malaria
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Tafenoquine Combinations for Improved Radical Cure Efficacy of Plasmodium Vivax [NA]
A clinical trial update investigating tafenoquine combinations to improve radical cure efficacy for uncomplicated Plasmodium vivax malaria; …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Safety, Immunogenicity and Efficacy Study of PvRII/Matrix-M in Healthy Thai Adults Living in Thailand ( MIST3 ) [Phase 2]
Phase 2 clinical trial evaluating safety, immunogenicity, and efficacy of PvRII/Matrix-M malaria vaccine in healthy Thai adults, currently n…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru
A feasibility study in Peru assessed using tafenoquine or primaquine for radical cure of Plasmodium vivax malaria after semi-quantitative G6…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases. [Phase 4]
Phase 4 clinical trial is evaluating the use of primaquine for Plasmodium vivax malaria in individuals with intermediate or deficient G6PD a…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: An Ultra-short Course of Primaquine for the Radical Cure of Vivax Malaria [Phase 3]
Phase 3 study evaluating an ultra-short course of primaquine for radical cure of Plasmodium vivax malaria; recruitment is not yet started.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax Malaria [Phase 2]
A Phase 2 clinical study is evaluating the safety and rapid anti-malarial activity of combining SJ733 with tafenoquine for radical cure of P…
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FDA approval · 2026-02-02FDA Approved: PRIMAQUINE PHOSPHATE — Supplemental Application (Sanofi-Aventis U.S. LLC)
FDA approved a supplemental application for Primaquine Phosphate from Sanofi-Aventis U.S. LLC, leading to a labeling update for the product.
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Phase IIa/b Trial of PvCS/Montanide ISA-51 Malaria Vaccine in Adults in Chocó, Colombia [Phase 2]
Phase IIa/b clinical trial evaluating the PvCS/Montanide ISA-51 malaria vaccine in adults in Chocó, Colombia. The study is not yet recruitin…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Safety and Immunogenicity of Pvs25-IMX313/Matrix-M1 Vaccine [EARLY_Phase 1]
An early Phase 1 trial evaluating the safety and immunogenicity of the Pvs25-IMX313/Matrix-M1 malaria vaccine was terminated, and results ha…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia [NA]
The trial update confirms the completion of a study evaluating a short course of primaquine for radical cure of Plasmodium vivax malaria in …
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Vivax Malaria Human Infection Studies in Thailand [NA]
This clinical trial update notes that recruitment is ongoing for vivax malaria human infection studies in Thailand, sponsored by the Univers…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: A Controlled Human Vivax Malaria Infection Study Through Inoculation of Infected Erythrocytes [NA]
The University of Oxford is conducting a controlled human vivax malaria infection study using inoculation of infected erythrocytes. The tria…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Vivax Elimination With Tafenoquine (VET) Study [Phase 4]
Phase 4 clinical trial update evaluating tafenoquine for eliminating Plasmodium vivax malaria; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea [NA]
A completed trial in Papua New Guinea evaluated a short course of primaquine for radical cure of Plasmodium vivax malaria with G6PD deficien…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: FocaL Mass Drug Administration for Vivax Malaria Elimination [Phase 3]
Phase 3 clinical trial evaluating focal mass drug administration to eliminate Plasmodium vivax malaria; recruitment is ongoing, sponsored by…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Clinical Trial to Evaluate the Safety and Immunogenicity of the Vivaxin Vaccine for Malaria Caused by Plasmodium Vivax." [Phase 1]
Phase 1 clinical trial to evaluate the safety and immunogenicity of the Vivaxin vaccine for Plasmodium vivax malaria; currently not yet recr…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Comparative Study of Thrombocytopenia in Plasmodium Vivax and Falciparum Malaria
This clinical trial update reports the completion and results of a comparative study on thrombocytopenia in Plasmodium vivax malaria versus …
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older [Phase 3]
A Phase 3 interventional trial in India comparing tafenoquine vs primaquine, each given with chloroquine, for treatment of Plasmodium vivax …
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: ACT vs CQ With Tafenoquine for P. Vivax Mono-infection [Phase 4]
Phase 4 clinical trial comparing artemisinin-based combination therapy (ACT) versus chloroquine with tafenoquine for Plasmodium vivax malari…
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: VAC069: A Study of Blood-stage Controlled Human P. Vivax Infection [EARLY_Phase 1]
This update reports completion of VAC069, a Phase 1 study evaluating blood-stage controlled human Plasmodium vivax infection, with results p…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Rigorous Assessment of P. Vivax Relapses and Primaquine Efficacy for Radical Cure [Phase 4]
Phase 4 clinical trial assessing the efficacy of primaquine for radical cure of Plasmodium vivax malaria has completed.
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Southeast Asia Dose Optimization of Tafenoquine [Phase 4]
A Phase 4 clinical trial in Southeast Asia is evaluating dose optimization of tafenoquine for Plasmodium vivax malaria and is currently recr…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients [Phase 2]
A Phase 2 trial comparing different primaquine regimens for Plasmodium vivax malaria in patients with glucose-6-phosphate dehydrogenase defi…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Study to Evaluate Primaquine for Radical Cure of Uncomplicated Plasmodium Vivax Malaria in Children [Phase 2]
A Phase 2 clinical trial evaluating primaquine for radical cure of uncomplicated Plasmodium vivax malaria in children has completed.
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Short Course Radical Cure of P. Vivax Malaria in Nepal [Phase 4]
This clinical trial update reports the completion of a Phase 4 study in Nepal evaluating a short-course radical cure for Plasmodium vivax ma…