Plasmodium Vivax Malaria
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru
A feasibility study in Peru assessed using tafenoquine or primaquine for radical cure of Plasmodium vivax malaria after semi-quantitative G6…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Phase IIa/b Trial of PvCS/Montanide ISA-51 Malaria Vaccine in Adults in Chocó, Colombia [Phase 2]
Phase IIa/b clinical trial evaluating the PvCS/Montanide ISA-51 malaria vaccine in adults in Chocó, Colombia. The study is not yet recruitin…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Safety and Immunogenicity of Pvs25-IMX313/Matrix-M1 Vaccine [EARLY_Phase 1]
An early Phase 1 trial evaluating the safety and immunogenicity of the Pvs25-IMX313/Matrix-M1 malaria vaccine was terminated, and results ha…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia [NA]
The trial update confirms the completion of a study evaluating a short course of primaquine for radical cure of Plasmodium vivax malaria in …
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: A Controlled Human Vivax Malaria Infection Study Through Inoculation of Infected Erythrocytes [NA]
The University of Oxford is conducting a controlled human vivax malaria infection study using inoculation of infected erythrocytes. The tria…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Vivax Elimination With Tafenoquine (VET) Study [Phase 4]
Phase 4 clinical trial update evaluating tafenoquine for eliminating Plasmodium vivax malaria; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea [NA]
A completed trial in Papua New Guinea evaluated a short course of primaquine for radical cure of Plasmodium vivax malaria with G6PD deficien…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: FocaL Mass Drug Administration for Vivax Malaria Elimination [Phase 3]
Phase 3 clinical trial evaluating focal mass drug administration to eliminate Plasmodium vivax malaria; recruitment is ongoing, sponsored by…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Clinical Trial to Evaluate the Safety and Immunogenicity of the Vivaxin Vaccine for Malaria Caused by Plasmodium Vivax." [Phase 1]
Phase 1 clinical trial to evaluate the safety and immunogenicity of the Vivaxin vaccine for Plasmodium vivax malaria; currently not yet recr…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Comparative Study of Thrombocytopenia in Plasmodium Vivax and Falciparum Malaria
This clinical trial update reports the completion and results of a comparative study on thrombocytopenia in Plasmodium vivax malaria versus …
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: VAC069: A Study of Blood-stage Controlled Human P. Vivax Infection [EARLY_Phase 1]
This update reports completion of VAC069, a Phase 1 study evaluating blood-stage controlled human Plasmodium vivax infection, with results p…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Rigorous Assessment of P. Vivax Relapses and Primaquine Efficacy for Radical Cure [Phase 4]
Phase 4 clinical trial assessing the efficacy of primaquine for radical cure of Plasmodium vivax malaria has completed.
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients [Phase 2]
A Phase 2 trial comparing different primaquine regimens for Plasmodium vivax malaria in patients with glucose-6-phosphate dehydrogenase defi…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: Short Course Radical Cure of P. Vivax Malaria in Nepal [Phase 4]
This clinical trial update reports the completion of a Phase 4 study in Nepal evaluating a short-course radical cure for Plasmodium vivax ma…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar [NA]
This clinical trial update describes the efficacy of focal primaquine mass administration to eliminate Plasmodium vivax malaria in northern …
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: VAC071: A Study to Assess Efficacy of the ChAd63/MVA PvDBP Vaccines [Phase 2]
Phase 2 trial investigating the ChAd63/MVA PvDBP vaccines for Plasmodium vivax malaria has completed with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2022-03-02Clinical Trial Update: P.Vivax Treatment Trial [Phase 1, Phase 2]
Clinical trial update for a Plasmodium vivax treatment showing completed Phase 1 and Phase 2 studies.
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil [NA]
Clinical trial evaluating three regimens of chloroquine and primaquine for treatment of Plasmodium vivax malaria completed with posted resul…
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria [Phase 2]
Phase 2 pediatric pharmacokinetics, safety, and efficacy study of tafenoquine for Plasmodium vivax malaria has been completed with results p…
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria [Phase 3]
Phase 3 trial evaluating tafenoquine co-administered with dihydroartemisinin-piperaquine for radical cure of Plasmodium vivax malaria has co…
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve Adults [Phase 1, Phase 2]
Clinical trial update for a malaria vaccine study (VMP001 with AS01B adjuvant) in healthy adults shows completed Phase 1/2 with posted resul…
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: Papua New Guinean Duffy Negativity And Vivax Malar
Clinical trial status update indicates the study examining Duffy negativity and Plasmodium vivax malaria in Papua New Guinea has been termin…
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria [Phase 3]
Phase 3 clinical trial comparing tafenoquine to primaquine in Plasmodium vivax malaria to evaluate incidence of hemolysis, safety, and effic…
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CLINICAL_TRIALS trial_result · 2018-03-01Clinical Trial Update: Assessment of Any Potential Retinal Effects of Tafenoquine (TQ) [Phase 1]
Phase 1 trial completed that assessed potential retinal effects of tafenoquine in patients with Plasmodium vivax malaria.
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CLINICAL_TRIALS trial_result · 2018-01-25Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults [Phase 2]
Phase 2 trial assessing tafenoquine for Plasmodium vivax treatment in adults; study is terminated with results posted.