Plasmodium Vivax Malaria
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate [Phase 1]
A Phase 1 pharmacokinetic study assessing a single dose of tafenoquine co-administered with either artemether+lumefantrine or dihydroartemis…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: PpPfs25/ISA51 and ScPvs25/ISA51 Vaccines for Malaria [Phase 1]
Phase 1 clinical trial update reporting completion of a study evaluating two malaria vaccines, PpPfs25/ISA51 and ScPvs25/ISA51, for Plasmodi…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Tafenoquine Thorough QTc Study in Healthy Subjects [Phase 1]
Phase 1 thorough QTc study of tafenoquine in healthy subjects has been completed to assess potential effects on the QT interval.
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Phase Ia Study of ChAd63/MVA PvDBP [Phase 1]
A Phase Ia study of the ChAd63/MVA PvDBP vaccine for malaria caused by Plasmodium vivax has been completed.
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Efficacy and Safety of Dihydroartemisinin-piperaquine (DHP) for the Treatment of Uncomplicated Malaria
A completed trial evaluating the efficacy and safety of dihydroartemisinin-piperaquine for treating uncomplicated malaria caused by Plasmodi…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Artemether-lumefantrine vs Chloroquine for Uncomplicated P. Vivax Malaria in Malaysia [Phase 3]
Phase 3 trial in Malaysia comparing artemether-lumefantrine with chloroquine for uncomplicated Plasmodium vivax malaria; current status is u…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution [Phase 1]
Phase 1 study assessing how the dissolution profile influences the pharmacokinetics of single oral doses of Tafenoquine tablets and a Tafeno…
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Ethiopia Antimalarial in Vivo Efficacy Study 2012 [Phase 4]
This is a completed Phase 4 clinical trial conducted in Ethiopia evaluating an antimalarial for in vivo efficacy against Plasmodium vivax ma…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Chlorproguanil/Dapsone Compared With Chloroquine and SP for Vivax Malaria [Phase 3]
A Phase 3 trial comparing chlorproguanil/dapsone with chloroquine and sulfadoxine-pyrimethamine for Plasmodium vivax malaria has completed.
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CLINICAL_TRIALS trial_result · 2016-09-30Clinical Trial Update: Antimalarial Drug Susceptibility and Molecular Characterization of Plasmodium Vivax Isolates in Vietnam [Phase 4]
Phase 4 trial update from Vietnam assesses antimalarial drug susceptibility and molecular characteristics of Plasmodium vivax isolates; the …
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or Vivax [Phase 2]
A Phase IIa study of the malaria candidate DSM265 for Plasmodium falciparum and Plasmodium vivax malaria has completed.
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Safety and Efficacy of Chloroquine and Primaquine for Vivax Malaria in Bhutan
A completed clinical trial assessed the safety and efficacy of chloroquine in combination with primaquine for vivax malaria in Bhutan.
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CLINICAL_TRIALS trial_result · 2016-04-28Clinical Trial Update: Comparison Between 7 and 14 Day Primaquine Combined With Dihydroartemisinin-piperaquine or 3 Day Chloroquine Radical Cure of P. Vivax (BPD) [Phase 3]
Phase 3 trial comparing 7-day versus 14-day primaquine regimens used with dihydroartemisinin-piperaquine or a 3-day chloroquine radical cure…
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CLINICAL_TRIALS trial_result · 2016-03-23Clinical Trial Update: Evaluating the Efficacy of Chloroquine for the Treatment of Plasmodium Vivax Infections in Central Vietnam [Phase 4]
A Phase 4 trial is evaluating the efficacy of chloroquine for Plasmodium vivax malaria in Central Vietnam; no results are reported yet.
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax Infection [Phase 2, Phase 3]
Completed Phase 2/Phase 3 trial assessing whether chloroquine alone is as effective as chloroquine with primaquine for Plasmodium vivax mala…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: Primaquine Pharmacokinetics in Lactating Women and Their Infants [Phase 1]
Phase 1 study assessing the pharmacokinetics of primaquine in lactating women and their infants for Plasmodium vivax malaria. The trial stat…
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: Investigation of Short Course, High Dose Primaquine Treatment for Liver Stages of Plasmodium Vivax Infection [Phase 4]
A Phase 4 clinical trial update evaluating a short-course, high-dose primaquine regimen for liver-stage Plasmodium vivax malaria.
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: Assessment of Plasmodium Vivax Chloroquine Resistance in Cambodia: [Phase 4]
Phase 4 clinical trial conducted in Cambodia to assess chloroquine resistance in Plasmodium vivax malaria; study has completed.
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects [Phase 1]
A Phase 1 trial evaluated the safety, tolerability and pharmacokinetics of OZ439 in healthy male and female volunteers.
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CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection [Phase 2]
Phase 2 clinical trial evaluating the efficacy, tolerability, and pharmacokinetics of OZ439 in adults with acute, uncomplicated malaria due …
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CLINICAL_TRIALS trial_result · 2014-05-21Clinical Trial Update: Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and Morbidity [Phase 4]
A Phase 4 clinical trial update evaluating whether liver- and blood-stage treatment affects subsequent reinfection and morbidity from malari…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Parasitic Clearance and Recurrence Rates Among Patients With Vivax Malaria
This clinical trial update reports on parasite clearance and recurrence rates in patients with Plasmodium vivax malaria.
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CLINICAL_TRIALS trial_result · 2013-08-29Clinical Trial Update: Study of ACTs Plus Primaquine for Uncomplicated Plasmodium Vivax Malaria [Phase 3]
A Phase 3 trial evaluating artemisinin-based combination therapy (ACT) plus primaquine for uncomplicated Plasmodium vivax malaria has comple…
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CLINICAL_TRIALS trial_result · 2013-07-18Clinical Trial Update: Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria [Phase 3]
Phase 3 trial comparing artesunate-amodiaquine to chloroquine for efficacy and tolerability in uncomplicated Plasmodium vivax malaria has co…
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: Pilot Human Study of Tinidazole Efficacy For Radical Cure Of Plasmodium Vivax [Phase 2]
Phase 2 pilot study evaluating tinidazole for radical cure of Plasmodium vivax malaria has been completed.