Plasmodium Falciparum Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-08-07Clinical Trial Update: Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, Thailand [NA]
A completed clinical trial evaluated the efficacy of artesunate-mefloquine combination therapy for Plasmodium falciparum malaria in Trat Pro…
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CLINICAL_TRIALS safety_alert · 2012-04-27Clinical Trial Update: Safety of Artemether - Lumefantrine, and Other Malaria Drugs and Their Effect on the Auditory Function [Phase 4]
Phase 4 safety update examining whether artemether-lumefantrine and other malaria drugs affect auditory function.
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CLINICAL_TRIALS trial_result · 2012-04-05Clinical Trial Update: Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria [Phase 4]
Phase 4 trial evaluating the efficacy of the amodiaquine-artesunate combination in treating uncomplicated Plasmodium falciparum malaria in c…
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CLINICAL_TRIALS trial_result · 2012-04-02Clinical Trial Update: Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis [NA]
This trial evaluated immunization with different doses of Plasmodium falciparum sporozoites under chloroquine prophylaxis. The study status …
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CLINICAL_TRIALS trial_result · 2012-03-30Clinical Trial Update: Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria [NA]
A completed clinical trial assessed the efficacy of two standard treatments for uncomplicated Plasmodium falciparum malaria: amodiaquine-art…
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CLINICAL_TRIALS trial_result · 2012-01-31Clinical Trial Update: Assessing the Efficacy of Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria Infection in Children [Phase 3]
This clinical trial update reports the completion of a Phase 3 study evaluating artemisinin-based combination therapies for uncomplicated Pl…
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CLINICAL_TRIALS trial_result · 2011-07-27Clinical Trial Update: Chloroquine Alone or in Combination for Malaria in Children in Malawi [Phase 3]
Phase 3 trial in Malawi evaluated chloroquine alone and in combination for treating Plasmodium falciparum malaria in children; results were …
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CLINICAL_TRIALS trial_result · 2011-06-28Clinical Trial Update: Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
Phase 2 dose-ranging study of ferroquine in combination with artesunate for uncomplicated Plasmodium falciparum malaria in African adults an…
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CLINICAL_TRIALS research · 2011-05-26Clinical Trial Update: Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
This clinical trial update describes a Phase 2 study evaluating fosmidomycin in combination with clindamycin for acute uncomplicated Plasmod…
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CLINICAL_TRIALS trial_result · 2011-05-10Clinical Trial Update: Trial of Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine for the Treatment of Uncomplicated Malaria in India [Phase 2, Phase 3]
Completed Phase 2/3 trial comparing azithromycin plus chloroquine versus sulfadoxine-pyrimethamine plus chloroquine for uncomplicated Plasmo…
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CLINICAL_TRIALS trial_result · 2011-04-26Clinical Trial Update: Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum [Phase 2]
Pfizer-sponsored Phase 2 trial evaluating azithromycin with chloroquine versus chloroquine alone for eradication of asymptomatic Plasmodium …
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CLINICAL_TRIALS trial_result · 2011-03-16Clinical Trial Update: Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function [Phase 4]
Phase 4 trial evaluating potential auditory effects of artemether-lumefantrine and other malaria drugs; results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2010-12-09Clinical Trial Update: Safety and Effectiveness of Artemisinin-based Combination Therapies (ACTs) With Repeated Treatments for Uncomplicated Falciparum Malaria Over a Three-year Period [Phase 4]
Phase 4 trial update evaluating the safety and effectiveness of repeated use of artemisinin-based combination therapies for uncomplicated Pl…
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CLINICAL_TRIALS trial_result · 2010-11-09Clinical Trial Update: Comparison of Three Plasmodium Falciparum Isolates in an Experimental Human Malaria Infection [NA]
This clinical trial compared three Plasmodium falciparum isolates in an experimental human malaria infection and is marked as completed.
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CLINICAL_TRIALS trial_result · 2010-11-09Clinical Trial Update: Re-exposure of EHMI-8 Human Volunteers to Live Malaria Sporozoites [NA]
The trial NCT00757887 reports a re-exposure study in humans to live Plasmodium falciparum malaria sporozoites; the study is completed.
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CLINICAL_TRIALS trial_result · 2010-10-18Clinical Trial Update: A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™ [Phase 1]
Phase 1 pharmacokinetic study in healthy Asian and Caucasian volunteers to characterize the PK profile of Eurartesim; the trial has complete…
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CLINICAL_TRIALS trial_result · 2010-09-14Clinical Trial Update: Pharmacokinetic of Mefloquine-Artesunate in Plasmodium Falciparum Malaria Infection in Pregnancy [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluating the pharmacokinetics of the Mefloquine-Artesunate combination for Plasmodium falciparum mala…
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CLINICAL_TRIALS trial_result · 2010-08-27Clinical Trial Update: Azithromycin Combination Therapy for Malaria [Phase 2]
A Phase 2 trial sponsored by NIAID evaluating azithromycin in combination therapy for Plasmodium falciparum malaria has completed.
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CLINICAL_TRIALS trial_result · 2010-08-27Clinical Trial Update: CQSP in Malawi: Chloroquine and Sulfadoxine-pyrimethamine Efficacy for the Treatment of Malaria in Malawi [Phase 4]
Phase 4 trial in Malawi evaluated the efficacy of chloroquine and sulfadoxine-pyrimethamine for treating malaria caused by Plasmodium falcip…
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CLINICAL_TRIALS trial_result · 2010-08-10Clinical Trial Update: Phase II AMA-1 Malaria Vaccine FMP2.1/AS02A Trial in Mali [Phase 2]
Phase II malaria vaccine trial (AMA-1 FMP2.1/AS02A) conducted in Mali has completed with results posted.
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CLINICAL_TRIALS trial_result · 2010-07-27Clinical Trial Update: Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian Amazon [NA]
A completed clinical trial evaluating the efficacy of Fansidar (pyrimethamine/sulfadoxine) for treating uncomplicated malaria caused by Plas…
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CLINICAL_TRIALS trial_result · 2010-07-07Clinical Trial Update: The Effect of Paracetamol in the Treatment of Non-severe Malaria in Children in Guinea-Bissau [Phase 4]
This Phase 4 trial assesses whether adding paracetamol influences treatment outcomes for non-severe malaria in children in Guinea-Bissau.
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CLINICAL_TRIALS trial_result · 2010-06-29Clinical Trial Update: Cohort Study in Uganda Comparing Artesunate + Amiodaquine (Coarsucam) Versus Artemether + Lumenfantrine (Coartem) in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks [Phase 4]
A Phase 4 cohort trial in Uganda comparing artesunate plus amodiaquine (Coarsucam) versus artemether plus lumefantrine (Coartem) for treatme…
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CLINICAL_TRIALS trial_result · 2010-06-23Clinical Trial Update: Cohort Study in Senegal Comparing Artesunate + Amiodaquine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks [Phase 4]
Phase 4 trial in Senegal evaluating artesunate plus amodiaquine for repeated uncomplicated Plasmodium falciparum malaria attacks; study comp…
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CLINICAL_TRIALS research · 2010-02-25Clinical Trial Update: Dihydroartemisinin- Piperaquine Versus Artemether- Lumefantrine in the Treatment Uncomplicated Plasmodium Falciparum Malaria in Sudan [Phase 4]
This clinical trial update compares dihydroartemisinin-piperaquine with artemether-lumefantrine for treating uncomplicated Plasmodium falcip…