Plasmodium Falciparum Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-04-12Clinical Trial Update: Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly [Phase 1]
Phase 1 trial evaluating the safety and immunogenicity of the EBA-175 RII-NG malaria vaccine administered intramuscularly.
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CLINICAL_TRIALS trial_result · 2013-03-29Clinical Trial Update: EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly in Semi-immune Adults [Phase 1]
Phase 1 trial assessing the intramuscular EBA-175 RII-NG malaria vaccine in semi-immune adults has been completed.
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CLINICAL_TRIALS trial_result · 2013-03-15Clinical Trial Update: Phase Ib Trial of Two Virosome Formulated Malaria Vaccine Components (PEV 301, PEV 302) in Tanzania [Phase 1]
A Phase Ib/Phase 1 trial evaluating two virosome-formulated malaria vaccine components, PEV 301 and PEV 302, in Tanzania has completed.
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Efficacy of Artemether-lumefantrine, Artesunate-amodiaquine and Dihydroartemisinin-piperaquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Malawi [NA]
This completed clinical trial in Malawi evaluates the efficacy of three artemisinin-based combination therapies—artemether-lumefantrine, art…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Efficacy, Safety and Pharmacokinetic of ArtequinTM P. Falciparum Malaria [Phase 2]
Phase 2 trial of Artequin for Plasmodium falciparum malaria assessing efficacy, safety, and pharmacokinetics has completed.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Interactions Between Artemether-lumefantrine and Antiretrovirals in HIV-patients With Uncomplicated Malaria in Tanzania [Phase 4]
Phase 4 clinical trial evaluating interactions between artemether-lumefantrine and antiretrovirals in HIV-infected patients with uncomplicat…
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CLINICAL_TRIALS trial_result · 2012-11-16Clinical Trial Update: EP1300 Polyepitope DNA Vaccine Against Plasmodium Falciparum Malaria [Phase 1]
Phase 1 trial evaluating the EP1300 polyepitope DNA vaccine for Plasmodium falciparum malaria has completed.
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CLINICAL_TRIALS trial_result · 2012-11-01Clinical Trial Update: Azithromycin Combination Therapy for the Treatment of Uncomplicated Falciparum Malaria in Bangladesh [Phase 2]
Phase 2 clinical trial in Bangladesh evaluating azithromycin in combination therapy for uncomplicated Plasmodium falciparum malaria has comp…
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CLINICAL_TRIALS trial_result · 2012-09-27Clinical Trial Update: Amodiaquine Plus Artesunate Versus Lapdap Plus Artesunate in the Treatment of Uncomplicated P. Falciparum Malaria in Malawi [Phase 4]
Phase 4 clinical trial comparing amodiaquine plus artesunate versus Lapdap plus artesunate for uncomplicated Plasmodium falciparum malaria i…
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CLINICAL_TRIALS trial_result · 2012-09-11Clinical Trial Update: Efficacy and Effectiveness of Combined Therapy for Uncomplicated Malaria Treatment in Peru
A completed clinical trial in Peru evaluated the efficacy and real-world effectiveness of a combined therapy for uncomplicated malaria due t…
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CLINICAL_TRIALS trial_result · 2012-09-11Clinical Trial Update: Efficacy of Chloroquine + Sulfadoxine Pyrimethamine Versus Artemether + Lumefantrine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in the Philippines [NA]
Clinical trial completed comparing chloroquine plus sulfadoxine-pyrimethamine against artemether plus lumefantrine for uncomplicated Plasmod…
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CLINICAL_TRIALS trial_result · 2012-08-07Clinical Trial Update: Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, Thailand [NA]
A completed clinical trial evaluated the efficacy of artesunate-mefloquine combination therapy for Plasmodium falciparum malaria in Trat Pro…
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CLINICAL_TRIALS trial_result · 2012-04-05Clinical Trial Update: Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria [Phase 4]
Phase 4 trial evaluating the efficacy of the amodiaquine-artesunate combination in treating uncomplicated Plasmodium falciparum malaria in c…
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CLINICAL_TRIALS trial_result · 2012-04-02Clinical Trial Update: Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis [NA]
This trial evaluated immunization with different doses of Plasmodium falciparum sporozoites under chloroquine prophylaxis. The study status …
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CLINICAL_TRIALS trial_result · 2012-03-30Clinical Trial Update: Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria [NA]
A completed clinical trial assessed the efficacy of two standard treatments for uncomplicated Plasmodium falciparum malaria: amodiaquine-art…
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CLINICAL_TRIALS trial_result · 2012-01-31Clinical Trial Update: Assessing the Efficacy of Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria Infection in Children [Phase 3]
This clinical trial update reports the completion of a Phase 3 study evaluating artemisinin-based combination therapies for uncomplicated Pl…
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CLINICAL_TRIALS trial_result · 2011-07-27Clinical Trial Update: Chloroquine Alone or in Combination for Malaria in Children in Malawi [Phase 3]
Phase 3 trial in Malawi evaluated chloroquine alone and in combination for treating Plasmodium falciparum malaria in children; results were …
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CLINICAL_TRIALS trial_result · 2011-06-28Clinical Trial Update: Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
Phase 2 dose-ranging study of ferroquine in combination with artesunate for uncomplicated Plasmodium falciparum malaria in African adults an…
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CLINICAL_TRIALS trial_result · 2011-05-10Clinical Trial Update: Trial of Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine for the Treatment of Uncomplicated Malaria in India [Phase 2, Phase 3]
Completed Phase 2/3 trial comparing azithromycin plus chloroquine versus sulfadoxine-pyrimethamine plus chloroquine for uncomplicated Plasmo…
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CLINICAL_TRIALS trial_result · 2011-04-26Clinical Trial Update: Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum [Phase 2]
Pfizer-sponsored Phase 2 trial evaluating azithromycin with chloroquine versus chloroquine alone for eradication of asymptomatic Plasmodium …
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CLINICAL_TRIALS trial_result · 2011-03-16Clinical Trial Update: Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function [Phase 4]
Phase 4 trial evaluating potential auditory effects of artemether-lumefantrine and other malaria drugs; results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2010-12-09Clinical Trial Update: Safety and Effectiveness of Artemisinin-based Combination Therapies (ACTs) With Repeated Treatments for Uncomplicated Falciparum Malaria Over a Three-year Period [Phase 4]
Phase 4 trial update evaluating the safety and effectiveness of repeated use of artemisinin-based combination therapies for uncomplicated Pl…
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CLINICAL_TRIALS trial_result · 2010-11-09Clinical Trial Update: Comparison of Three Plasmodium Falciparum Isolates in an Experimental Human Malaria Infection [NA]
This clinical trial compared three Plasmodium falciparum isolates in an experimental human malaria infection and is marked as completed.
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CLINICAL_TRIALS trial_result · 2010-11-09Clinical Trial Update: Re-exposure of EHMI-8 Human Volunteers to Live Malaria Sporozoites [NA]
The trial NCT00757887 reports a re-exposure study in humans to live Plasmodium falciparum malaria sporozoites; the study is completed.
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CLINICAL_TRIALS trial_result · 2010-10-18Clinical Trial Update: A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™ [Phase 1]
Phase 1 pharmacokinetic study in healthy Asian and Caucasian volunteers to characterize the PK profile of Eurartesim; the trial has complete…