Plasmodium Falciparum Malaria
📧 Sign up to get email alerts when something new happens for Plasmodium Falciparum Malaria.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Low Dose Primaquine for Clearance of Gametocytes [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating low-dose primaquine to clear gametocytes in malaria has completed.
-
CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: Artemether-lumefantrine (AL) Versus Artesunate + Amodiaquine (ASAQ) for the Treatment of Uncomplicated Falciparum Malaria in Burkina Faso [Phase 4]
Phase 4 trial comparing artemether-lumefantrine (AL) with artesunate–amodiaquine (ASAQ) for treating uncomplicated Plasmodium falciparum mal…
-
CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kg [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial update assessing the efficacy, safety, and pharmacokinetics of an artemether-lumefantrine dispersible table…
-
CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Tracking Resistance to Artemisinin (TRAC) [Phase 4]
The Phase 4 TRAC trial tracking resistance to artemisinin in Plasmodium falciparum malaria has been completed.
-
CLINICAL_TRIALS trial_result · 2015-04-23Clinical Trial Update: Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ Challenge [Phase 1]
A Phase 1 trial evaluating how Plasmodium falciparum exposure and sickle cell trait influence infection rates and kinetics after IV administ…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: A Study of Safety and Immunogenicity of a Malaria Vaccine Candidate [Phase 1]
A Phase 1 study evaluating safety and immunogenicity of a malaria vaccine candidate has completed. The sponsor reported completion of a Phas…
-
CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa [Phase 3]
Phase 3 trial evaluating the combination of azithromycin and chloroquine for parasitological clearance and pharmacokinetics in asymptomatic …
-
CLINICAL_TRIALS trial_result · 2015-01-09Clinical Trial Update: A Phase I/IIa Study of the Safety, Immunogenicity and Efficacy of FMP2.1/AS01B, an Asexual Blood-Stage Vaccine for Plasmodium Falciparum Malaria [Phase 1, Phase 2]
This Phase 1/2a study evaluated the safety, immunogenicity, and efficacy of the malaria vaccine FMP2.1/AS01B for Plasmodium falciparum malar…
-
CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjects [Phase 1]
A Phase 1 trial evaluated the safety, tolerability and pharmacokinetics of OZ439 in healthy male and female volunteers.
-
CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: Efficacy and Safety of a Single Low-dose Primaquine for the Clearance of Gametocytes [Phase 4]
This Phase 4 trial evaluates the efficacy and safety of a single low-dose primaquine for clearance of gametocytes in Plasmodium falciparum m…
-
CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection [Phase 2]
Phase 2 clinical trial evaluating the efficacy, tolerability, and pharmacokinetics of OZ439 in adults with acute, uncomplicated malaria due …
-
CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: A Safety and Efficacy Study of ChAd63/MVA METRAP + RTS,S [Phase 1, Phase 2]
Safety and efficacy study of ChAd63/MVA METRAP combined with RTS,S in malaria has completed Phase 1 and Phase 2.
-
CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria [Phase 2]
Phase 2 trial evaluating a three-day course of azithromycin plus chloroquine for uncomplicated Plasmodium falciparum malaria; results were p…
-
CLINICAL_TRIALS trial_result · 2014-05-21Clinical Trial Update: Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and Morbidity [Phase 4]
A Phase 4 clinical trial update evaluating whether liver- and blood-stage treatment affects subsequent reinfection and morbidity from malari…
-
CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,S [Phase 1, Phase 2]
This report summarizes safety and early efficacy data from Phase 1/2 trials of two malaria vaccine candidates, FMP1 and RTS,S, in Plasmodium…
-
CLINICAL_TRIALS trial_result · 2014-03-18Clinical Trial Update: Efficacy of Artemether/Lumefantrine for the Treatment of Uncomplicated Malaria. [Phase 4]
A Phase 4 trial assessed the efficacy of artemether/lumefantrine for uncomplicated Plasmodium falciparum malaria. The study has completed.
-
CLINICAL_TRIALS trial_result · 2014-02-28Clinical Trial Update: Superiority of ArTiMist Versus Quinine in Children With Severe Malaria [Phase 3]
A Phase 3 trial reports that ArTiMist is superior to quinine in treating children with severe Plasmodium falciparum malaria.
-
CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma [NA]
A completed clinical trial assessed how malaria, hookworm infection, and schistosomiasis affect iron absorption and utilization in adolescen…
-
CLINICAL_TRIALS trial_result · 2013-08-23Clinical Trial Update: Azithromycin Combination Therapy for the Treatment of Severe Malaria [Phase 2]
Phase 2 trial evaluating azithromycin in combination therapy for severe Plasmodium falciparum malaria has completed.
-
CLINICAL_TRIALS trial_result · 2013-06-12Clinical Trial Update: Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in Uganda [Phase 3]
This Phase 3 trial evaluated the gametocytocidal efficacy and safety of primaquine in adults with uncomplicated Plasmodium falciparum malari…
-
CLINICAL_TRIALS trial_result · 2013-06-03Clinical Trial Update: AMA1-C1/Alhydrogel + CpG 7909 for Malaria [Phase 1]
A Phase 1 clinical trial of the AMA1-C1 malaria vaccine formulated with Alhydrogel and CpG 7909 has completed, evaluating safety and immunog…
-
CLINICAL_TRIALS trial_result · 2013-05-28Clinical Trial Update: Optimisation of Controlled Human Malaria Infection Using Sporozoites Administered by Needle and Syringe [NA]
This is an update on a clinical trial optimizing controlled human malaria infection using Plasmodium falciparum sporozoites delivered by nee…
-
CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Rapid Diagnostic Tests for Assessment of Initial Clearance and Detection of Recurrent Malaria Infections
This clinical trial update reports the completion of a study evaluating rapid diagnostic tests for assessing initial clearance and detecting…
-
CLINICAL_TRIALS trial_result · 2013-04-29Clinical Trial Update: Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis [NA]
A completed clinical trial evaluating immunization with Plasmodium falciparum sporozoites under chloroquine versus mefloquine prophylaxis fo…
-
CLINICAL_TRIALS trial_result · 2013-04-12Clinical Trial Update: ICC-1132 - Candidate Vaccine Against P Falciparum Malaria [Phase 1]
Phase 1 clinical trial update showing completion of Phase 1 testing for ICC-1132, a vaccine candidate targeting Plasmodium falciparum malari…