Plasmodium Falciparum Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-03-27Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31F [Phase 1]
Phase 1 trial update reporting safety, tolerability, pharmacokinetics, and pharmacodynamics of TB31F for malaria caused by Plasmodium falcip…
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CLINICAL_TRIALS trial_result · 2023-01-13Clinical Trial Update: Safety and Preliminary Protective Efficacy of Genetically Attenuated GA2 Parasites. [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating safety and preliminary protective efficacy of genetically attenuated GA2 parasites for Plasmodium …
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CLINICAL_TRIALS trial_result · 2022-05-11Clinical Trial Update: Safety and Efficacy of NF135 CPS Immunization [NA]
Clinical trial update for NF135 CPS immunization shows termination with posted results, involving malaria falciparum and controlled human ma…
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine [Phase 2, Phase 3]
Phase 2/3 trial comparing pyronaridine-artesunate to artemether-lumefantrine for malaria shows efficacy and safety data from completed study…
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CLINICAL_TRIALS trial_result · 2022-01-28Clinical Trial Update: Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) [Phase 3]
Phase 3 trial update on seasonal malaria vaccination (RTS,S/AS01) and seasonal malaria chemoprevention (SP/AQ) completed with results posted…
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CLINICAL_TRIALS trial_result · 2021-12-15Clinical Trial Update: Safety and Protective Efficacy of Pb(PfCS@UIS4) [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and protective efficacy of Pb(PfCS@UIS4); results completed with posted results in 2021.
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Comparison of Arterolane-piperaquine Versus Arterolane-piperaquine+Mefloquine Versus Artemether-lumefantrine in Kenyan Children [Phase 3]
Phase 3 trial comparing arterolane-piperaquine alone, with mefloquine, and artemether-lumefantrine in Kenyan children for treatment of Plasm…
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CLINICAL_TRIALS trial_result · 2021-09-17Clinical Trial Update: Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria [Phase 2]
Phase II dose-ranging study of Pyronaridine/Artesunate in adults with Plasmodium falciparum malaria completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-05-21Clinical Trial Update: NMRC-M3V-Ad-PfCA Vaccine - Clinical Trial 1 [Phase 1, Phase 2]
This clinical trial update reports completed Phase 1/Phase 2 results for the NMRC-M3V-Ad-PfCA vaccine targeting Plasmodium falciparum.
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Assessment of the Therapeutic Efficacy and Tolerability of the Artesunate/Amodiaquina Combination and Artemether/Lumefantrine Combination, Treatment of Uncomplicated P. Falciparum Malaria in the Department of Chocó (Colombia) [Phase 4]
Phase 4 clinical trial assessing artesunate/amodiaquine vs artemether/lumefantrine for uncomplicated Plasmodium falciparum malaria with comp…
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: Drug Combinations of Atovaquone-Proguanil (AP) With ACT [Phase 4]
Phase 4 clinical trial update evaluating combinations of atovaquone-proguanil with artemisinin-based combination therapy for drug-resistant …
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Targeted Active Case Detection Among High Risk Populations in Southern Lao Peoples Democratic Republic [Phase 4]
Phase 4 trial update evaluating targeted active case detection in high-risk populations for Plasmodium falciparum malaria in southern Lao PD…
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CLINICAL_TRIALS trial_result · 2020-12-11Clinical Trial Update: Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults. [Phase 2]
Phase 2 trial update assessing safety and immunogenicity of RTS,S/AS02A and RTS,S/AS01B malaria vaccines in malaria-experienced adults.
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: DSM265 Chemoprophylaxis of Plasmodium Falciparum Malaria [Phase 1]
Phase 1 trial updates for DSM265 as a chemoprophylaxis against Plasmodium falciparum malaria; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: SJ733 Induced Blood Stage Malaria Challenge Study [Phase 1]
Phase 1 clinical trial update for SJ733 inducing blood-stage malaria, completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Fetal Immunity to Falciparum Malaria
This clinical trial update reports a completed study investigating fetal immunity to Plasmodium falciparum malaria sponsored by NIAID.
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Malaria Prevalence in Children
A completed clinical trial update reporting malaria prevalence in children caused by Plasmodium falciparum, sponsored by NIAID.
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Malaria Transmission and Immunity in Highland Kenya
This clinical trial update documents the completed status of a study on malaria transmission and immunity in highland Kenya. The sponsor is …
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Plasmodium Resistance in A. Gambiae
Completed clinical trial update examining Plasmodium resistance in Anopheles gambiae in the context of malaria (Plasmodium falciparum).
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CLINICAL_TRIALS trial_result · 2018-12-12Clinical Trial Update: Efficacy and Safety of Artesunate + Amodiaquine With SLD of Primaquine for Treatment of Falciparum Malaria in Zanzibar [Phase 4]
Phase 4 clinical trial updating the efficacy and safety of artesunate plus amodiaquine with primaquine as single low dose in treating Plasmo…
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CLINICAL_TRIALS trial_result · 2018-12-07Clinical Trial Update: Efficacy of Artesunate + Amodiaquine Versus Artemether-lumefantrine for Falciparum Malaria in Zanzibar, 2005 [Phase 4]
Phase 4 trial comparing artesunate + amodiaquine versus artemether-lumefantrine for Plasmodium falciparum malaria conducted in Zanzibar; com…
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CLINICAL_TRIALS trial_result · 2018-12-06Clinical Trial Update: Tolerability and Efficacy of Artemether-Lumefantrine Versus Artesunate + Amodiaquine in Zanzibar [Phase 4]
Phase 4 trial comparing tolerability and efficacy of artemether-lumefantrine versus artesunate + amodiaquine for Plasmodium falciparum malar…
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CLINICAL_TRIALS trial_result · 2018-11-26Clinical Trial Update: Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America [Phase 1, Phase 2]
Phase I/II clinical trial update for a malaria vaccine in adults in the United States (completed; results posted).
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CLINICAL_TRIALS trial_result · 2018-11-26Clinical Trial Update: Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America [Phase 1, Phase 2]
A Phase 1/2 clinical trial of a malaria vaccine conducted in adults in the United States has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-10-05Clinical Trial Update: Triple Antimalarial Combination to Accelerate the Parasite Clearance and to Prevent the Selection of Resistant Parasites [Phase 2]
Phase 2 clinical trial evaluating a triple antimalarial combination to speed parasite clearance and reduce emergence of resistance in drug-r…