Peripheral T-cell Lymphoma Not Otherwise Specified
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies. [Phase 1, Phase 2]
This document describes a Phase 1/Phase 2 clinical trial evaluating AZD3470 as a monotherapy or in combination with other anticancer agents …
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Aclarubicin Plus Cyclophosphamide, Vincristine, and Prednisone (CAOP) in Patients With Previously Untreated Peripheral T-Cell Lymphoma [Phase 2]
Phase 2 trial evaluating CAOP (Aclarubicin, Cyclophosphamide, Vincristine, Prednisone) for previously untreated peripheral T-cell lymphoma. …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma [Phase 1]
A Phase 1 clinical trial is evaluating intravenous vesicular stomatitis virus in patients with peripheral T-cell lymphoma and related condit…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma [Phase 3]
Soquelitinib is being studied in a Phase 3 trial versus standard of care for relapsed/refractory peripheral T-cell lymphomas, including PTCL…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma [Phase 2]
A Phase 2 trial evaluating adding duvelisib or CC-486 to standard therapy for several peripheral T-cell lymphomas has been suspended.
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma [Phase 1, Phase 2]
Clinical trial update for AUTO4 in TRBC1-positive T-cell lymphomas shows Phase 1/2 results with the study terminated and results posted.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Combination With Romidepsin [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pembrolizumab in combination with romidepsin for recurrent or refractory T-cell lymphomas; the study i…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas [Phase 2]
Phase 2 clinical trial evaluating duvelisib as maintenance therapy for peripheral T-cell lymphomas, currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas [Phase 1]
Phase 1 trial evaluating ruxolitinib in combination with CHOP chemotherapy as first-line therapy for untreated nodal Follicular Helper T-cel…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Ro Plus CHOEP as First Line Treatment Before HSCT in Young Patients With Nodal Peripheral T-cell Lymphomas [Phase 1, Phase 2]
A Phase 1/2 clinical trial (NCT02223208) evaluates Ro plus CHOEP as first-line therapy before hematopoietic stem cell transplantation in you…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas [Phase 1, Phase 2]
This is a completed Phase 1/2 clinical trial from MD Anderson evaluating AFM13 and AFM13-NK in patients with recurrent or refractory CD30-po…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating durvalumab with or without lenalidomide in patients with relapsed or refractory cutaneous or periph…
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: An Open-Label Phase 2 Trial of Nanatinostat Plus Valganciclovir in Patients With EBV+ Relapsed/Refractory Lymphomas [Phase 2]
An open-label Phase 2 trial evaluating nanatinostat plus valganciclovir in EBV-positive relapsed/refractory lymphomas has been terminated, w…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Daratumumab Plus Gemcitabine, Dexamethasone, Cisplatin in pt R/R CD38+ PTCL-NOS, AITL and TFH [Phase 2]
Phase 2 trial of daratumumab with gemcitabine, dexamethasone, and cisplatin in relapsed/refractory CD38+ peripheral T-cell lymphoma subtypes…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy [Phase 3]
Phase 3 trial to evaluate whether high-dose chemotherapy followed by autologous stem cell transplantation improves survival in peripheral T-…
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CLINICAL_TRIALS trial_result · 2021-06-18Clinical Trial Update: Combination Chemotherapy & Lenalidomide in Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating combination chemotherapy with lenalidomide in newly diagnosed peripheral T-cell lymphoma (multiple subtypes) ha…
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CLINICAL_TRIALS research · 2018-03-15Clinical Trial Update: CHOP vs GEM-P in 1st Line Treatment of T-cell Lymphoma, Multicentre Phase II Study [Phase 2]
Multicentre Phase II trial comparing CHOP versus GEM-P as first-line therapy for various peripheral T-cell lymphomas; current study status i…
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: CTOP/ITE/MTX Compared With CHOP as the First-line Therapy for Newly Diagnosed Young Patients With T Cell Lymphoma [Phase 4]
A Phase 4 clinical trial compares the CTOP/ITE/MTX regimen against CHOP as first-line therapy for newly diagnosed young patients with variou…
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CLINICAL_TRIALS research · 2016-07-26Clinical Trial Update: GDP in Frontline Chemotherapy for Patients With PTCL-NOS [Phase 2]
Phase 2 clinical trial evaluating GDP (gemcitabine, cisplatin, dexamethasone) as frontline chemotherapy for peripheral T-cell lymphoma not o…
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CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Study of Bortezomib and Panobinostat in Treating Patients With Relapsed/Refractory Peripheral T-cell Lymphoma or NK/T-cell Lymphoma [Phase 2]
A completed Phase 2 study evaluating the combination of bortezomib and panobinostat in relapsed or refractory peripheral T-cell lymphomas an…