Perihilar Cholangiocarcinoma

• CLINICAL_TRIALS research · 2026-04-03
  Clinical Trial Update: LIver TrAnspLantation for Non-resectable Peri-HIlar cholangioCArcinoma (LITALHICA) [NA]

  A clinical trial update notes that a study evaluating liver transplantation for non-resectable perihilar cholangiocarcinoma is currently rec…

• CLINICAL_TRIALS research · 2026-03-13
  Clinical Trial Update: A Prospective, Single-Arm, Phase II Study: PD-L1 Monoclonal Antibody + Chemoradiotherapy as Bridge Therapy to Liver Transplantation for Locally Advanced Perihilar Cholangiocarcinoma (ACHIEVE-LT) [Phase 2]

  This is a Phase II prospective, single-arm trial evaluating a PD-L1 monoclonal antibody combined with chemoradiotherapy as a bridge to liver…

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: PD-1 Antibody Plus GEMOX as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma [Phase 2]

  Phase 2 trial evaluating a PD-1 antibody plus GEMOX as postoperative adjuvant therapy for perihilar cholangiocarcinoma is currently recruiti…

• CLINICAL_TRIALS trial_result · 2026-01-28
  Clinical Trial Update: Perioperative Treatment of High-risk Resectable CCA With HAIC Plus A+T: Neobrave CCA [Phase 2]

  This clinical trial update reports termination of a Phase 2 study evaluating perioperative hepatic arterial infusion chemotherapy with A+T (…

• CLINICAL_TRIALS trial_result · 2026-01-16
  Clinical Trial Update: Preoperative Right Hepatic Artery Embolization for Locally Advanced Bismuth IIIb and IV Perihilar Cholangiocarcinoma [NA]

  This clinical trial update covers preoperative right hepatic artery embolization for locally advanced, non-resectable Bismuth IIIb/IV perihi…

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• CLINICAL_TRIALS trial_result · 2025-12-18
  Clinical Trial Update: Biliary Drainage Plus HAIC in Locally Advanced pCCA [Phase 2]

  Phase 2 trial evaluating biliary drainage plus hepatic arterial infusion chemotherapy in locally advanced perihilar cholangiocarcinoma has c…

• CLINICAL_TRIALS research · 2025-12-01
  Clinical Trial Update: Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma [Phase 2]

  Phase 2 clinical trial evaluating durvalumab in combination with intraductal radiofrequency ablation for unresectable extrahepatic cholangio…

• CLINICAL_TRIALS research · 2025-09-09
  Clinical Trial Update: Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)

  This clinical trial POELH-III evaluates preoperative evaluation of lymph nodes in cholangiocarcinoma and is currently not yet recruiting.

• CLINICAL_TRIALS research · 2025-09-02
  Clinical Trial Update: Volume-Restricted Resection for Perihilar Cholangiocarcinoma

  This clinical trial update describes a study on volume-restricted resection for perihilar cholangiocarcinoma. It notes that enrollment has n…

• CLINICAL_TRIALS research · 2025-07-31
  Clinical Trial Update: Liver Transplantation for Non-resectable Perihilar Cholangiocarcinoma [NA]

  A clinical trial sponsored by Oslo University Hospital is evaluating liver transplantation for non-resectable perihilar cholangiocarcinoma (…

• CLINICAL_TRIALS trial_result · 2025-07-10
  Clinical Trial Update: Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer

  This clinical trial update reports the termination of a feasibility study evaluating multi-platform profiling of resected biliary tract canc…

• CLINICAL_TRIALS research · 2025-05-23
  Clinical Trial Update: Liver Transplantation for Unresectable Perihilar Cholangiocarcinoma

  A clinical trial is evaluating liver transplantation for unresectable perihilar cholangiocarcinoma (Klatskin tumor). The study is currently …

• CLINICAL_TRIALS research · 2025-04-11
  Clinical Trial Update: Neoadjuvant Gemcitabine and Cisplatin in Combination With Perioperative Pembrolizumab Versus Upfront Surgery for Patients With Primary Resectable and Borderline Resectable Perihilar and Distal Cholangiocarcinoma [Phase 2, Phase 3]

  A Phase 2/3 clinical trial compares neoadjuvant gemcitabine and cisplatin with perioperative pembrolizumab versus upfront surgery in patient…

• CLINICAL_TRIALS trial_result · 2025-03-18
  Clinical Trial Update: Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)

  Expanded Access for ABC294640 (Yeliva) in advanced cholangiocarcinoma has been closed and is no longer available.

• CLINICAL_TRIALS research · 2024-12-06
  Clinical Trial Update: Robotically Assisted Surgery For Perihilar Cholangiocarcinoma: A Prospective Study

  Prospective study evaluating robotically assisted surgery for perihilar cholangiocarcinoma is currently recruiting. Sponsored by Azienda Osp…

• CLINICAL_TRIALS trial_result · 2017-03-01
  Clinical Trial Update: Single Versus Multiple Deployment of Metallic Stents for Inoperable Malignant Hilar Biliary Obstruction [NA]

  This clinical trial update notes the completion of a study comparing single versus multiple deployments of metallic stents for inoperable ma…