Pemphigus
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: Efficacy and Safety of Different Doses of Rituximab Therapy in Pemphigus Patients
A completed clinical trial evaluated the efficacy and safety of different rituximab dosing regimens in patients with pemphigus.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Comparison of a Personalized Maintenance Therapy With the Standard Treatment in Pemphigus [Phase 4]
Phase 4 clinical trial update comparing personalized maintenance therapy with standard treatment in pemphigus; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: FARD (RaDiCo Cohort) (RaDiCo-FARD)
The RaDiCo-FARD clinical trial sponsored by INSERM is currently recruiting, studying a cohort of patients with inherited skin and ectodermal…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Clinical and Immunological Long-term Follow-up of Patients With Pemphigus Included in the "RITUXIMAB 3" Trial [Phase 3]
This clinical trial update provides long-term clinical and immunological follow-up data from pemphigus patients in the Phase 3 RITUXIMAB 3 t…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Identification of Vulnerability Factors in the Course of Pemphigus Patients [NA]
Clinical trial update investigating vulnerability factors in the progression of pemphigus; the study has completed.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: ONO-4059 Study in Patients With Steroid-resistant Pemphigus [Phase 3]
A Phase 3 clinical trial evaluating ONO-4059 for steroid-resistant pemphigus is currently recruiting.
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EMA approval · 2025-10-06EMA Authorised: Rixathon (rituximab) — Sandoz GmbH
EMA authorised Rixathon (rituximab) by Sandoz as a biosimilar to Rituxan for several autoimmune and hematologic diseases, expanding access t…
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EMA approval · 2025-07-14EMA Authorised: Ruxience (rituximab) — Pfizer Europe MA EEIG
The EMA authorised Ruxience, a rituximab biosimilar by Pfizer Europe MA EEIG, for several indications including chronic lymphocytic leukemia…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus [Phase 2]
A Phase 2 clinical trial conducted by The University of Hong Kong is evaluating intravenous immunoglobulin plus rituximab versus rituximab a…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: A Single Cycle of Intravenous Immunoglobulin as Adjuvant to Rituximab in Patients With Pemphigus: A Retrospective Cohort Study at a Tertiary Referral Center
A retrospective cohort study evaluates a single cycle of intravenous immunoglobulin as an adjuvant to rituximab in patients with pemphigus.
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: A Single-center Study of CM313 in Patients With Pemphigus [NA]
A single-center study evaluating CM313 in patients with pemphigus; the trial is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Assessment of the 1-year Relapse Rate in Patients with Pemphigus Treated According to the Revised Pemphigus PNDS
This clinical trial update reports on the 1-year relapse rate in patients with pemphigus treated according to the revised Pemphigus PNDS.
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Impact of a Lifestyle Program on Quality of Life in Pemphigus Patients [NA]
This entry notes a clinical trial evaluating a lifestyle program to improve quality of life in pemphigus patients. The study is not yet recr…
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CLINICAL_TRIALS research · 2024-10-10Clinical Trial Update: A Clinical Study of B007 in the Treatment of Pemphigus. [Phase 2, Phase 3]
This document reports an ongoing Phase 2/3 clinical study of B007 for pemphigus that is currently recruiting. Pemphigus is an autoimmune bli…
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CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: A Study of PRN1008 in Patients With Pemphigus [Phase 3]
Phase 3 study of PRN1008 in pemphigus was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: A Safety and Dose-Finding Study of SYNT001 in Subjects With Pemphigus (Vulgaris or Foliaceus) [Phase 1, Phase 2]
A safety and dose-finding study of SYNT001 in pemphigus (vulgaris or foliaceus) was conducted in Phase 1/2 and subsequently terminated; resu…
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CLINICAL_TRIALS trial_result · 2019-04-22Clinical Trial Update: Pharmacokinetics Study of Mycophenolic Acid in Patients With an Autoimmune Bullous Dermatose, Pemphigus or Cicatricial Pemphigoid. [Phase 3]
Phase 3 pharmacokinetics study of mycophenolic acid in patients with autoimmune bullous skin diseases (pemphigus and cicatricial pemphigoid)…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Role of Proteasomes in a Dermatological Autoimmune Disease: Bullous Pemphigoid
A clinical trial investigating the role of proteasomes in bullous pemphigoid has been terminated; the study included bullous pemphigoid, pem…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Comparison Between Rituximab Treatment and General Corticotherapy Treatment in Patients With Pemphigus [Phase 3]
Phase 3 clinical trial comparing rituximab to general corticosteroid therapy in pemphigus has completed.
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CLINICAL_TRIALS trial_result · 2016-12-22Clinical Trial Update: Immunoadsorption, Dexamethasone Pulse Therapy and Rituximab for Pemphigus [Phase 2]
A Phase 2 clinical trial evaluating a combination of immunoadsorption, dexamethasone pulse therapy, and rituximab for pemphigus has complete…
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis Pemphigus [EARLY_Phase 1]
An early-phase 1 trial evaluating sirolimus for pemphigus was terminated, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-02-19Clinical Trial Update: Wound Dressings for Pemphigus and Pemphigoid [NA]
This document provides a clinical trial update on the use of wound dressings for Pemphigus and Pemphigoid. The trial phase information is no…
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CLINICAL_TRIALS trial_result · 2014-10-30Clinical Trial Update: Comparative Study of Rituximab Versus Combination of Rituximab and Intravenous Cyclophosphamide in Severe Pemphigus [Phase 3]
An update on a Phase 3 trial comparing rituximab alone to rituximab plus intravenous cyclophosphamide in severe pemphigus.
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CLINICAL_TRIALS trial_result · 2013-06-18Clinical Trial Update: Effect of Anti CD20 in Pemphigus Desease [Phase 2, Phase 3]
Clinical trial update reporting results for anti-CD20 therapy in pemphigus across phase 2 and phase 3, with the study now completed.
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CLINICAL_TRIALS trial_result · 2013-04-08Clinical Trial Update: Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders [Phase 1]
A Phase 1 study evaluating hematopoietic stem cell support in patients with pemphigus, an autoimmune bullous skin disorder, has terminated.