Patent Foramen Ovale
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Abbott Structural Heart Device Registry
Abbott's Structural Heart Device Registry is currently recruiting to evaluate outcomes across several congenital and structural heart condit…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pulmonary Embolism and Right-to-Left Shunts
A Tufts Medical Center-led clinical trial update shows recruitment ongoing for a study on pulmonary embolism and right-to-left shunt-related…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure [NA]
A clinical trial is evaluating medical therapy with or without transcatheter closure of a patent foramen ovale in patients with patent foram…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years [Phase 3]
A Phase 3 clinical trial is evaluating PFO closure versus oral anticoagulants or antiplatelet therapy to prevent recurrent stroke in adults …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Discontinuation of Antithrombotic Treatment Following Patent Foramen Ovale Closure in Young Patients With Cryptogenic Stroke [NA]
A clinical trial update describing the plan to discontinue antithrombotic therapy after patent foramen ovale closure in young patients with …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: NobleStitch EL STITCH Trial is a PFO Comparative Trial [NA]
The NobleStitch EL STITCH Trial is a comparative study evaluating patent foramen ovale closure for stroke prevention and is currently recrui…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion [NA]
This clinical trial update describes a study comparing the Occlutech Flex II PFO Occluder to standard PFO occlusion in patients with stroke …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Non-Invasive Detection of Right-to-Left Cardiac Shunts
This clinical trial update describes a study evaluating a non-invasive method to detect right-to-left cardiac shunts in patients with patent…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Non-Invasive Detection of Pulmonary Right-to-Left Shunts Using the SONAS Ultrasound Device [NA]
A recruiting clinical trial evaluating a non-invasive SONAS ultrasound device to detect pulmonary right-to-left shunts in patients with here…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: CeraFlex PFO Closure System PMCF Study
A post-market clinical follow-up (PMCF) study for Lifetech Scientific's CeraFlex PFO Closure System is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine [NA]
A clinical trial comparing biodegradable and metal occluders for patients with patent foramen ovale and migraine is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study [NA]
The REDUCE Post Approval Study is evaluating antiplatelet strategies to reduce recurrent stroke in patients with patent foramen ovale treate…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Internal Microstructure of Patent Foramen Ovale Related to Stroke
A clinical trial is recruiting to investigate the internal microstructure of the patent foramen ovale and its relationship to stroke. The sp…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study
A clinical trial from National University Hospital, Singapore, investigating the relationship between ischemic stroke and patent foramen ova…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome
Update on the SECRETO Study Consortium trial investigating causes, triggers, and outcomes of cryptogenic stroke in young adults. The study i…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: WSO BEAT STROKE Initiative [NA]
This clinical trial update describes the WSO BEAT STROKE Initiative evaluating stroke and patent foramen ovale with related atrial fibrillat…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Russian Registry of Endovascular Closure of PFO
A Russian clinical trial registry entry for endovascular closure of patent foramen ovale is currently recruiting, sponsored by the National …
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Swartz Sheath With Angioplasty Guidewire-Assisted Technique for Patent Foramen Ovale Closure (STAGE-PFO) [NA]
Clinical trial update for the STAGE-PFO study evaluating a Swartz sheath with an angioplasty guidewire-assisted technique for patent foramen…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: Amplatzer PFO Occluder Post-marketing Surveillance Study
Post-marketing surveillance study for the Amplatzer PFO Occluder by Abbott Medical Devices is active but not recruiting. The study tracks sa…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: The PROOF Trial - Prospective, Open-label, Multicenter, Non-randomized Investigation on Percutaneous Patent Foramen Ovale (PFO) Closure Using the Occlutech PFO Occluder to Prevent Recurrence of Stroke in Patients With Cryptogenic Stroke and High Risk PFO
The PROOF trial, a prospective open-label multicenter non-randomized study evaluating percutaneous closure of patent foramen ovale with the …
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Long-term Procedural and Device Related Complications of PFO Closure
This clinical trial update describes a study evaluating long-term procedural and device-related complications of patent foramen ovale closur…
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CLINICAL_TRIALS research · 2019-02-04Clinical Trial Update: PFO ACCESS Registry
Clinical trial registry entry for the PFO ACCESS Registry (NCT00583401) indicates the study is no longer available, suggesting it has been t…
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CLINICAL_TRIALS research · 2016-09-07Clinical Trial Update: Patent Foramen Ovale and the Risk of Postoperative Delirium Following Elective Hip and Knee Arthroplasty Surgeries
A completed clinical trial investigating whether patent foramen ovale influences the risk of postoperative delirium after elective hip or kn…
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CLINICAL_TRIALS research · 2015-03-09Clinical Trial Update: Influence of Position on Detection of Patent Foramen Ovale by Simultaneous Transesophageal Echo and Transcranial Doppler
This entry reports an update on a study examining how body position affects detection of patent foramen ovale using simultaneous transesopha…
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CLINICAL_TRIALS research · 2011-06-30Clinical Trial Update: InterSEPT: In-Tunnel SeptRx European PFO Trial [NA]
An update on the InterSEPT European PFO trial by SeptRx, Inc. indicates the trial status is currently unknown.