Partial Epilepsy
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CLINICAL_TRIALS trial_result · 2026-08-13Clinical Trial Update: Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures [Phase 3]
A Phase 3 clinical trial evaluates cenobamate for safety and efficacy in pediatric subjects aged 2-17 with partial-onset seizures; study sta…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Recording "Fast Ripples" Using Microelectrodes During Stereo-encephalography in Patients With Drug-resistant Partial Epilepsy [NA]
A completed clinical trial evaluating recording fast ripples with microelectrodes during stereo-encephalography in people with drug-resistan…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW) [Phase 4]
A Phase 4 trial comparing low versus standard daily doses of antiepileptic drugs in newly diagnosed, previously untreated epilepsy. Results …
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Contribution of Genetics, Non-invasive Methods and Neuropsychology in Focal Cryptogenic Epilepsies [NA]
This completed clinical trial investigated the contribution of genetics, non-invasive methods, and neuropsychology in focal cryptogenic epil…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study
A completed pilot trial assessing cerebral oxygen saturation and cytochrome oxidase redox state in children with partial epilepsy.
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CLINICAL_TRIALS trial_result · 2023-03-15Clinical Trial Update: A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures [Phase 2]
A Phase 2 randomized trial of ganaxolone in adults with uncontrolled partial-onset seizures has completed and posted results.
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CLINICAL_TRIALS trial_result · 2023-01-17Clinical Trial Update: Open-label Extension to Protocol 1042-0600 [Phase 2]
Open-label extension study update for a Phase 2 trial in partial epilepsies; results posted after completion.
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures [Phase 2]
Phase 2 double-blind, randomized, placebo-controlled trial evaluating YKP3089 as adjunctive therapy for partial onset seizures; results were…
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CLINICAL_TRIALS trial_result · 2022-04-11Clinical Trial Update: Efficacy and Safety of YKP3089 in Subjects With Treatment Resistant Partial Onset Seizures [Phase 2]
Phase 2 trial update on YKP3089 for treatment-resistant partial onset seizures; results posted.
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Epilepsy [Phase 3]
Phase 3 trial results for deep brain stimulation of the anterior nucleus of the thalamus in partial epilepsy have been completed.
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Phase II BGG492 Capsule Extension for Partial Epilepsy [Phase 2]
Phase II extension trial update for BGG492 capsule in partial epilepsy (partial onset seizures) completed.
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CLINICAL_TRIALS trial_result · 2019-11-27Clinical Trial Update: Efficacy of Fluoxetine in Reducing Ictal Hypoventilation in Patients With Partial Epilepsy [NA]
Clinical trial update evaluating fluoxetine for reducing ictal hypoventilation in patients with uncontrolled partial epilepsy has completed …
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CLINICAL_TRIALS trial_result · 2018-12-07Clinical Trial Update: PRX-00023 Therapy in Localization-Related Epilepsy [Phase 2]
Phase 2 trial update for PRX-00023 in localization-related epilepsy (temporal lobe). Trial status terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Brain P-gp and Inflammation in People With Epilepsy
This clinical trial update reports the completion of a study evaluating brain P-glycoprotein and inflammation in people with partial epileps…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Study of PK and Safety of OXC (Oxcarbazepine) XR (Extended Release) as Adjunctive Therapy in Pediatric Epilepsy Patients [Phase 1]
A Phase 1 study evaluated the pharmacokinetics and safety of oxcarbazepine extended-release as adjunctive therapy in pediatric patients with…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Serotonin Receptors in Seizure Disorders
An update on a completed clinical trial exploring the role of serotonin receptors in partial epilepsy, sponsored by the National Institute o…
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Randomized Controlled Trial to Assess Effects of Lacosamide on Sleep and Wake in Adults With Focal Epilepsy [Phase 4]
A Phase 4 randomized trial assessed lacosamide's effects on sleep and wakefulness in adults with focal epilepsy. The study completed and res…
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: Localizing the Epileptogenic Zone With High Resolution Electroencephalography [NA]
A completed clinical trial evaluated high-resolution electroencephalography to localize the epileptogenic zone in patients with partial epil…
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CLINICAL_TRIALS trial_result · 2015-08-20Clinical Trial Update: Levetiracetam Versus Oxcarbazepine as Monotherapy to Evaluate Efficacy and Safety in Subjects With Newly or Recently Diagnosed Partial Epilepsy [Phase 4]
A Phase 4 study compared levetiracetam with oxcarbazepine as monotherapy in patients with newly or recently diagnosed partial epilepsy, with…
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CLINICAL_TRIALS trial_result · 2014-12-19Clinical Trial Update: Study to Evaluate Pharmacokinetics and Tolerability of Multiple Doses of Eslicarbazepine Acetate and Oxcarbazepine [Phase 1]
Phase 1 study evaluating the pharmacokinetics and tolerability of multiple doses of eslicarbazepine acetate and oxcarbazepine in partial epi…
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CLINICAL_TRIALS trial_result · 2014-12-12Clinical Trial Update: Effect of Repeat Administration of Eslicarbazepine Acetate on the Pharmacokinetics of a Combined Oral Contraceptive [Phase 1]
Phase 1 study evaluating whether repeat administration of eslicarbazepine acetate affects the pharmacokinetics of a combined oral contracept…
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CLINICAL_TRIALS trial_result · 2014-11-26Clinical Trial Update: Hormonal and Lipid Levels in Male Subjects After a Switch From Carbamazepine to Lacosamide [Phase 3]
A Phase 3 trial assessing hormonal and lipid changes in male subjects after switching from carbamazepine to lacosamide for epilepsy; the stu…
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CLINICAL_TRIALS trial_result · 2014-07-22Clinical Trial Update: Vimpat® Added as Adjunctive Therapy to One Baseline Antiepileptic Drug
Trial evaluated Vimpat (lacosamide) as adjunctive therapy to one baseline antiepileptic drug in partial epilepsy; results have been posted a…
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CLINICAL_TRIALS trial_result · 2014-04-15Clinical Trial Update: Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) as Adjunctive Therapy for Refractory Partial Seizures [Phase 3]
Phase 3 trial updating on the efficacy and safety of eslicarbazepine acetate as adjunctive therapy for refractory partial seizures.
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: Evaluation of Efficacy and Safety of OXC XR as Adjunctive Therapy for Partial Seizures [Phase 3]
Phase 3 trial evaluating the efficacy and safety of OXC XR as adjunctive therapy for partial seizures; results have been posted.