Pancreatic Neuroendocrine Tumor
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CLINICAL_TRIALS trial_result · 2026-08-25Clinical Trial Results: Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors [Phase 2]
Phase 2 trial results for nab-sirolimus in patients with well-differentiated neuroendocrine tumors (NETs) of the gastrointestinal tract, lun…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Multicenter Trial of ESK981 in Patients With Select Solid Tumors [Phase 2]
This document reports a Phase 2 multicenter clinical trial of ESK981 in select solid tumors. The study is currently recruiting across specif…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) [Phase 2]
This Phase 2 trial update covers belzutifan (MK-6482) for advanced pheochromocytoma/paraganglioma, pancreatic neuroendocrine tumors, von Hip…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors [Phase 1]
This clinical trial update outlines a phase 1 study testing the addition of sunitinib malate to Lutetium-177 dotatate (Lutathera) for pancre…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors [Phase 2]
This entry describes a Phase 2 clinical trial on the natural history and management of Von Hippel-Lindau–associated pancreatic neuroendocrin…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Testing the Addition of An Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Pancreatic Neuroendocrine Tumors [Phase 1]
Phase 1 trial evaluating addition of M3814 (Peposertib) to Lutetium-177 dotatate for pancreatic neuroendocrine tumors; study currently activ…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors [Phase 2, Phase 3]
A Phase 2/Phase 3 trial is evaluating Zanzalintinib versus Everolimus in locally advanced or metastatic neuroendocrine tumors, including pan…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Endoscopic Ultrasound-Guided Radiofrequency Ablation for Pancreatic Cystic Neoplasms and Pancreatic Neuroendocrine Tumors [NA]
A clinical trial is actively recruiting to evaluate endoscopic ultrasound-guided radiofrequency ablation for pancreatic cystic neoplasms and…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs. [Phase 1]
This is a Phase 1 clinical trial update for RayzeBio's RYZ401 in subjects with solid tumors expressing somatostatin receptors; the study is …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001) [NA]
A clinical trial update shows ongoing recruitment for an individualized mRNA neoantigen vaccine, mRNA-0523-L001, to treat several advanced e…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy [Phase 3]
Phase 3 trial update for RYZ101 versus standard of care in patients with inoperable, well-differentiated SSTR-positive gastroenteropancreati…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Plasma cfDNA Fragmentomics for Early pNET Detection and Differential Diagnosis of Solid Pancreatic Tumors
A clinical trial sponsored by Fudan University is recruiting to evaluate plasma cfDNA fragmentomics for early detection of pancreatic neuroe…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating a gene-modified immune cell therapy after a conditioning regimen for metastatic melanoma and other metas…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors [Phase 2]
A Phase 2 trial investigates the combination of atezolizumab and bevacizumab in several rare solid tumors, with the study currently not recr…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Management of Pancreatic Cystic Lesions Using Artificial Intelligence Based on EUS and Multimodal Data
A clinical trial is actively recruiting to evaluate AI-based management of pancreatic cystic lesions using endoscopic ultrasound and multimo…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas [Phase 2]
A Phase 2 clinical trial evaluating temozolomide plus SurVaxM (survivin long peptide vaccine) for progressing metastatic neuroendocrine carc…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders
A Mayo Clinic-sponsored clinical trial update recruiting to collect medical information and tissue samples from patients with pancreatic can…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: AI-Powered Precision Decision-Making for Pancreatic Diseases
An ongoing clinical trial evaluating AI-powered precision decision-making for pancreatic diseases. Recruitment is currently in progress.
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: CompArative Analysis Between, Thymic, pulmonaRy and Pancreatic Well Differentiated High Grade Neuroendocrine Tumors
An ongoing European Institute of Oncology trial is comparing thymic, pulmonary, and pancreatic well-differentiated high-grade neuroendocrine…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors [Phase 1]
Phase 1 trial of a survivin long peptide vaccine in patients with metastatic neuroendocrine tumors has completed, assessing safety and preli…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: FTT PET/CT in Pancreatic Neuroendocrine Tumors [Phase 1]
A Phase 1 clinical trial evaluating FTT PET/CT imaging in pancreatic neuroendocrine tumors is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms
The trial is currently recruiting to evaluate a genetic predisposition testing program in patients with pancreatic neuroendocrine tumor.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Pancreatic Neuroendocrine Tumour - Optimal Surgical Debulking or Not [NA]
This clinical trial in pancreatic neuroendocrine tumor is evaluating whether optimal surgical debulking provides benefit. It is currently re…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Outcomes After Laparoscopic Versus Open Pancreaticoduodenectomy [NA]
A clinical trial evaluating outcomes after laparoscopic versus open pancreaticoduodenectomy for pancreatic and periampullary cancers is curr…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Abemaciclib in Treating Patients With Advanced, Refractory, and Unresectable Digestive System Neuroendocrine Tumors [Phase 2]
This Phase 2 trial evaluates Abemaciclib in patients with advanced, unresectable, and/or metastatic digestive system neuroendocrine tumors; …