Pancreatic Ductal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: JDB153 Combined With Serplulimab for Pancreatic Cancer After Standard Treatment Failure [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating JDB153 in combination with Serplulimab for refractory pancreatic ductal adenocarcinoma; the study is not…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Endoscopic Ultrasound Radiofrequency Ablation and Immunotherapy Pembrolizumab for Locally Advanced Unresectable and Metastatic Pancreatic Duct Adenocarcinoma [Phase 2]
Phase 2 study evaluating endoscopic ultrasound-guided radiofrequency ablation combined with pembrolizumab for locally advanced unresectable …
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Oncological Safety of Spleen Preservation in Left Pancreatectomy for Pancreatic Ductal Adenocarcinoma (SPLENDID)
This clinical trial evaluates the oncological safety of spleen preservation during left pancreatectomy for resectable pancreatic ductal aden…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma [Phase 1]
Phase 1 clinical trial update evaluating the combination of ivosidenib with mFOLFIRINOX in patients with resectable pancreatic ductal adenoc…
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CLINICAL_TRIALS withdrawal · 2025-09-04Clinical Trial Update: PET Imaging Using 64Cu-Tz-SarAr and hu5B1-TCO in People With Pancreatic, Colorectal, Bladder Cancer or Cancers With Elevated CA19.9 [Phase 1]
Phase 1 trial evaluating PET imaging agents 64Cu-Tz-SarAr and hu5B1-TCO in pancreatic, colorectal, and bladder cancers (including cancers wi…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Imaging Study of 18F-FAC PET Scans to Assess Standard Treatment in People With Pancreatic Cancer [EARLY_Phase 1]
A phase 1 imaging trial using 18F-FAC PET scans to assess standard treatment in people with pancreatic cancer, currently active but not recr…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: First-line Regimen With QL1706 Plus Chemo ± Bev in PDAC Patients [Phase 2]
This entry describes an ongoing Phase 2 trial evaluating first-line therapy with QL1706 plus chemotherapy with or without bevacizumab in pan…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: CD318-targeted CAR-T Cell Therapy in Patients With Pancreatic Cancer (ResCPa) [Phase 1, Phase 2]
A CD318-targeted CAR-T cell therapy (ResCPa) is being studied in pancreatic cancer patients in Phase 1 and Phase 2, and the trial is not yet…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Mesopancreatic Excision for Pancreatic Duct Adenocarcinoma. [NA]
A clinical trial update on mesopancreatic excision for pancreatic ductal adenocarcinoma, which is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating the KRAS G12D-targeting agent RMC-9805 is currently recruiting for multiple solid tumor indications incl…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC [Phase 1, Phase 2]
This clinical trial update describes a master protocol for TCR-modified T cell therapy targeting an HLA-restricted KRAS antigen, studied in …
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours [Phase 1]
A Phase 1 study of [225Ac]-FPI-2059 in adults with solid tumours was terminated.
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma [Phase 2]
Phase 2 clinical trial update on the Ad5.F35-hGCC-PADRE cancer vaccine for pancreatic, colorectal, gastric, and esophageal adenocarcinomas; …
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation [Phase 2]
The Miami 'EMPIRE' trial is a Phase 2 study evaluating immuno-radiation for eradication of metastatic pancreatic ductal adenocarcinoma. The …
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Artificial Intelligence-powered Low-Dose Computed Tomography for Screening of Pancreatic Cancer
A clinical trial update describes an artificial intelligence–driven, low-dose CT screening method being studied for pancreatic cancer and re…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer [Phase 2]
Phase 2 trial evaluating niraparib in combination with dostarlimab for germline or somatic BRCA1/2 and PALB2-mutated metastatic pancreatic c…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Study of GnP RegimenCombined With Serplulimab and Stereotactic Body Radiation Therapy as First-line Treatment for Locally Advanced Pancreatic Cancer [Phase 2]
Phase 2 clinical trial evaluating gemcitabine/nab-paclitaxel (GnP) plus serplulimab and stereotactic body radiation therapy as first-line tr…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Trial of First-line L-glutamine With Gemcitabine and Nab-paclitaxel in Advanced Pancreatic Cancer [Phase 1]
A Phase 1 clinical trial evaluating first-line L-glutamine in combination with gemcitabine and nab-paclitaxel for advanced pancreatic cancer…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Early Detection of PDAC in Patients With Chronic Pancreatitis
A completed clinical trial evaluating early detection approaches for pancreatic ductal adenocarcinoma in patients with chronic pancreatitis.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Clinical Performance of Medical Device Software "Lipidica 1.0" for Processing Data Generated by Lipidomic Analysis in Pancreatic Cancer Screening [NA]
An update on the clinical performance study of Lipidica 1.0, a medical device software that analyzes lipidomic data for pancreatic cancer sc…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor [Phase 1, Phase 2]
Update on a Phase I/II autologous engineered TCR T-cell therapy trial for advanced pancreatic ductal adenocarcinoma, non-small cell lung can…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Anti-CD38 Antibody With KRAS Vaccine and Anti-PD-1 Antibody in Subjects With Pancreatic Ductal Adenocarcinoma and Refractory Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial tests an anti-CD38 antibody with a KRAS vaccine and an anti-PD-1 antibody in pancreatic ductal adenocarcinoma and r…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: OSE2101+FOLFIRI, or FOLFIRI Maintenance After FOLFIRINOX-based Induction Therapy in Advanced or Metastatic PDAC [Phase 2]
This entry describes a Phase 2 trial evaluating OSE2101 with FOLFIRI, or FOLFIRI maintenance after FOLFIRINOX induction, in advanced or meta…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer [Phase 2]
Phase 2 clinical trial evaluating neoadjuvant FOLFIRINOX plus pembrolizumab followed by surgery for resectable pancreatic ductal adenocarcin…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: A Study to Determine if the Drug, Pyrvinium Pamoate, is Safe and Tolerable in Patients With Pancreatic Cancer [Phase 1]
This document updates the status of a Phase 1 trial evaluating Pyrvinium Pamoate for safety and tolerability in pancreatic cancer. The study…