Pancreatic Ductal Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2025-11-19Clinical Trial Update: Phase I Study of Cosibelimab and Balixafortide in Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1]
This clinical trial update notes a Phase I study of cosibelimab in combination with balixafortide for metastatic pancreatic ductal adenocarc…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Study of Changes and Characteristics of Genes in Patients With Pancreatic Cancer for Better Treatment Selection
A completed study examining genetic changes and gene characteristics in pancreatic ductal adenocarcinoma patients to help tailor treatments.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Phase II Clinical Study Evaluating SSGJ-706 in Combination Therapy for Advanced Gastrointestinal Cancers [Phase 2]
Phase II clinical study evaluating SSGJ-706 in combination therapy for advanced gastrointestinal cancers is not yet recruiting. The study in…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: HRS-4642 Combined With Nimotuzumab in the Treatment of Recurrent or Metastatic Pancreatic Ductal Adenocarcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating HRS-4642 in combination with nimotuzumab for recurrent or metastatic pancreatic ductal adenocarcinoma …
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer [Phase 2]
Phase 2 study of Botensilimab in metastatic pancreatic ductal adenocarcinoma is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer
A UC San Francisco-backed clinical trial is evaluating whether hyperpolarized 13C MRI can predict response to therapy in pancreatic ductal a…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS [Phase 1, Phase 2]
A Phase 1/Phase 2 study evaluating RMC-6236 in patients with advanced solid tumors harboring RAS mutations, including non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer [Phase 1, Phase 2]
ClinicalTrials.gov reports an ongoing Phase 1/2 study evaluating sonoporation in combination with chemotherapy for locally advanced or metas…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) [Phase 1, Phase 2]
Spevatamig (PT886) is being studied as a monotherapy or in combination with chemotherapy and/or immune checkpoint inhibitors in Phase 1/2 tr…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Adaptive Radiation for Locally Advanced Unresectable Pancreatic Cancer [NA]
An ongoing clinical trial is evaluating adaptive radiation therapy for locally advanced, unresectable pancreatic ductal adenocarcinoma and i…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE) [Phase 2, Phase 3]
A Phase 2/3 trial evaluating the diagnostic performance of GEH300079 (68Ga) PET/CT for detecting pancreatic cancer in patients with colorect…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: 24BRO681 : Alternating Gnp and mFOLFIRINOX for BR-PDAC [Phase 2]
Phase 2 trial evaluating alternating gemcitabine/nab-paclitaxel and modified FOLFIRINOX in BRCA-related pancreatic ductal adenocarcinoma.
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describing safety, tolerability, and imaging with [68Ga]Ga-DPI-4452 and safety, tolerability, and efficacy…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial update reports on the combination of MGC018 and MGD019 in participants with advanced solid tumors, including castration-r…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies [Phase 1]
A Phase 1 study of JANX008 in advanced or metastatic solid tumors is currently recruiting, evaluating multiple indications including Non-Sma…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins. [EARLY_Phase 1]
An early-phase study evaluating the Ga-68 labeled FF58 radiotracer in selected solid tumors overexpressing integrins has been terminated.
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: Safety and Efficacy of Mitazalimab in Combination With Chemotherapy in Pancreatic Cancer Patients [Phase 1, Phase 2]
This document reports a Phase 1/2 clinical trial evaluating mitazalimab in combination with chemotherapy for metastatic pancreatic ductal ad…
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CLINICAL_TRIALS other · 2025-10-02Clinical Trial Update: Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma [Phase 2]
Phase 2 imaging trial evaluating 68Ga-FAPI-46 PET/CT for imaging cancer-associated fibroblasts in localized pancreatic ductal adenocarcinoma…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC) [Phase 1]
Phase 1 clinical trial update for ProAgio in pancreatic ductal adenocarcinoma, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Safety and Tolerance of Epigenetic and Immunomodulating Drugs Combined With Chemotherapeutics in Patients Suffering From Advanced Pancreatic Cancer [Phase 1, Phase 2]
This completed Phase 1/2 study evaluated the safety and tolerability of combining epigenetic and immunomodulating drugs with standard chemot…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: A Single-Arm, Open-Label, Multicenter Phase I/II Clinical Study of GFH276 in Patients With RAS-Mutant Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a single-arm, open-label Phase I/II study of GFH276 in patients with RAS-mutant advanced solid tumors, …
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Utility of ctDNA in Early Switch of First-line mFOLFIRINOX in Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating whether circulating tumor DNA can guide an early switch from first-line mFOLFIRINOX in metastatic pancre…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Prospectively Defining Metastatic Pancreatic Ductal Adenocarcinoma Subtypes by Comprehensive Genomic Analysis
A clinical trial designed to prospectively define subtypes of metastatic pancreatic ductal adenocarcinoma using comprehensive genomic analys…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas [Phase 3]
Phase 3 clinical trial evaluating Glubran 2, a modified cyanoacrylate tissue adhesive, for use in soft pancreas during pancreatic and periam…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: UCSF PANC Cyst Registry
Update on the UCSF PANC Cyst Registry clinical trial, which is currently recruiting and investigating pancreatic cysts and pancreatic neopla…