Pancreatic Cancer
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: LYNPARZA Pancreas Cancer Japan Post-Marketing Surveillance (PMS)
A post-marketing surveillance study for olaparib (LYNPARZA) in pancreatic cancer in Japan has completed.
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: SLOG vs mFOLFIRINOX as the First-line Treatment in Locally Advanced Uncresectable or Metastatic Pancreatic Cancer [Phase 2]
Completed Phase 2 trial comparing SLOG regimen to modified FOLFIRINOX as first-line therapy for locally advanced unresectable or metastatic …
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer [Phase 2]
Phase 2 clinical trial evaluating telotristat ethyl for weight stability in advanced pancreatic cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Paravertebral Block vs no Block in Open Pancreaticoduodenectomy [Phase 4]
A Phase 4 trial comparing paravertebral block to no block in open pancreaticoduodenectomy was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics [NA]
A clinical trial update for the HOPE-Genomics intervention aimed at improving cancer patients' knowledge of genomics, with results posted on…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Different Patterns of Target Delineation in SBRT for Locally Advanced Pancreatic Cancer [NA]
This clinical trial update presents completed results on different patterns of target delineation in SBRT for locally advanced pancreatic ca…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: A Trial of YL-13027 in Combination With Gemcitabine and Nab-paclitaxel in Patients With Refractory Metastatic Pancreatic Cancer [Phase 1]
Phase 1 trial evaluating YL-13027 in combination with gemcitabine and Nab-paclitaxel in patients with refractory metastatic pancreatic cance…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, Radiation Dosimetry, and PET Imaging Properties of 89Zr-labeled hNd2 (NMK89) in Patients With Pancreatic Cancer [Phase 1]
Phase 1 study of NMK89, a 89Zr-labeled hNd2 radiotracer, evaluating safety, tolerability, pharmacokinetics, radiation dosimetry, and PET ima…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Portal Vein Stenting for Malignant Obstruction: Feasibility, Safety, and Clinical Outcomes
This completed clinical trial evaluates portal vein stenting for malignant obstruction, reporting on feasibility and safety and detailing ob…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers [Phase 1]
Phase 1 clinical trial evaluating hypofractionated radiotherapy in combination with durvalumab (MEDI4736) and tremelimumab in patients with …
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy [NA]
This clinical trial update describes PROACTIVE, a study assessing surgical resection outcomes after neoadjuvant chemotherapy in locally adva…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Paricalcitol Addition to Chemotherapy in Patients With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma [Phase 2]
Clinical trial update on adding paricalcitol to chemotherapy for previously untreated metastatic pancreatic ductal adenocarcinoma; the Phase…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Cabozantinib and Pembrolizumab in Metastatic Pancreas [Phase 2]
A Phase 2 trial evaluating the combination of cabozantinib and pembrolizumab in metastatic pancreatic cancer has completed, with results pos…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies [NA]
A clinical trial is evaluating high dose-rate brachytherapy for unresectable primary and metastatic liver malignancies. The study is current…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005) [Phase 2]
Phase 2 trial evaluating pembrolizumab plus lenvatinib in previously treated patients with select solid tumors; results on efficacy and safe…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Anamorelin Study for Advanced Pancreatic Cancer [Phase 2]
Phase 2 trial of anamorelin in metastatic pancreatic cancer was terminated, with results posted on 2025-11-17.
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Clinical Trial of SOT102 Antibody Drug Conjugate in Patients With Advanced Gastric and Pancreatic Adenocarcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial of SOT102 antibody-drug conjugate in advanced gastric and pancreatic adenocarcinoma has been terminated; results ha…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial [NA]
A clinical trial update indicates the Comprehensive Radiobiology Assessment trial examining microenvironment effects of radiotherapy is curr…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors [Phase 1, Phase 2]
Phase I/II trial of autologous T cells engineered to express T-cell receptors (TCRs) in patients with solid tumors was terminated with resul…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: ABT-888 With Modified FOLFOX6 in Patients With Metastatic Pancreatic Cancer [Phase 1, Phase 2]
This update reports results from a Phase 1/2 trial of ABT-888 (veliparib) in combination with a modified FOLFOX6 regimen for metastatic panc…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 trial update reports termination of NUV-868 as monotherapy and in combination with olaparib or enzalutamide in adults with adva…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery [Phase 1]
A Phase 1 trial evaluating an investigational neoantigen vaccine for pancreatic cancer has completed, exploring the vaccine in the pre-surgi…
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Respiratory-gated Stereotactic Body Radiation Therapy for Adenocarcinoma of the Pancreas or Periampullary Region [NA]
This document provides an update on a completed clinical trial evaluating respiratory-gated SBRT for pancreatic adenocarcinoma and periampul…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Safety, Tolerability, and Efficacy of mFOLFIRINOX ± BNT321 as Adjuvant Therapy Following Curative Resection in Patients With Pancreatic Adenocarcinoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating the safety, tolerability, and efficacy of the modified FOLFIRINOX regimen with or without BNT321 as adjuvant ther…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors [Phase 2]
A Phase 2 trial evaluating niraparib in patients with advanced PALB2-mutated tumors was terminated; results have been posted for multiple so…