Palmoplantar Pustulosis
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase III Randomized Controlled Trial Evaluating the Efficacy and Safety of Tofacitinib Combined With Imatinib in Patients With Moderate-to-Severe Palmoplantar Pustulosis [Phase 3]
A Phase III randomized trial evaluating the efficacy and safety of combining tofacitinib with imatinib for moderate-to-severe palmoplantar p…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis [Phase 3]
A Phase 3 clinical trial evaluating the efficacy and safety of bimekizumab in palmoplantar pustulosis is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Clinical Observation of Xeligekimab in the Treatment of Moderate to Severe Palmoplantar Pustulosis [Phase 4]
A Phase 4 clinical trial update for Xeligekimab in treating moderate to severe Palmoplantar Pustulosis, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers
Clinical trial update notes ongoing sample collection from participants with acne, atopic dermatitis, chronic hand eczema, hidradenitis supp…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis [Phase 2]
Phase 2 clinical trial update evaluating the efficacy and safety of Delgocitinib cream 20 mg/g in adults with palmoplantar pustulosis, curre…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Efficacy and Tolerability of Deucravacitinib in the Management of Palmoplantar Pustulosis [NA]
A terminated clinical trial evaluated the efficacy and tolerability of Deucravacitinib in palmoplantar pustulosis, sponsored by Peking Unive…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: A Registry Study of Palmoplantar Pustulosis (PPP) Treatment Patterns, Disease Burden and Treatment Outcomes in Japan
A completed registry study in Japan examined how palmoplantar pustulosis is treated, the disease burden, and treatment outcomes.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Deucravacitinib for the Treatment of Palmoplantar Pustulosis [Phase 4]
A Phase 4 trial evaluating deucravacitinib for palmoplantar pustulosis was terminated, with results posted on 2025-12-16.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: A Prospective, Single-arm, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Ivarmacitinib in the Treatment of Palmoplantar Pustulosis [NA]
Prospective, single-arm, open-label study to evaluate the efficacy and safety of Ivarmacitinib in palmoplantar pustulosis. The trial is curr…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Phase 3, Randomized Study of Apremilast in Japanese Participants With Palmoplantar Pustulosis (PPP) [Phase 3]
Phase 3 randomized study of apremilast in Japanese participants with palmoplantar pustulosis has completed. Results have been posted.
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Construction of a Psoriasis and Psoriatic Arthritis Diagnostic Model Based on Multidimensional Nail Information
A study is being developed to build a diagnostic model for psoriasis and psoriatic arthritis based on multidimensional nail information; the…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: A Study to Test Long-term Treatment With Spesolimab in People With Palmoplantar Pustulosis (PPP) Who Took Part in Previous Studies With Spesolimab [Phase 2]
Clinical trial update reports termination of a Phase 2 long-term treatment study of Spesolimab for palmoplantar pustulosis and posted result…
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: A Phase 2b Study to Evaluate RIST4721 in Palmoplantar Pustulosis (PPP) [Phase 2]
Phase 2b trial of RIST4721 in palmoplantar pustulosis was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-02-14Clinical Trial Update: A Study of KHK4827 in Subjects With Palmoplantar Pustulosis [Phase 3]
Phase 3 trial of KHK4827 in palmoplantar pustulosis has been completed.
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CLINICAL_TRIALS trial_result · 2022-12-05Clinical Trial Update: Study of Subcutaneous Risankizumab Injection to Assess Change in Palmoplantar Pustulosis Area and Severity Index [PPPASI] in Adult Japanese Participants With Palmoplantar Pustulosis [Phase 3]
Phase 3 trial completed evaluating subcutaneous risankizumab for Palmoplantar Pustulosis (PPP) in adult Japanese participants, measuring PPP…
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CLINICAL_TRIALS trial_result · 2022-07-28Clinical Trial Update: A Study to Test How Effective and Safe Different Doses of BI 655130 Are in Patients With a Moderate to Severe Form of the Skin Disease Palmoplantar Pustulosis [Phase 2]
This Phase 2 trial update reports the completion and results posting for evaluating different doses of BI 655130 in adults with moderate-to-…
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CLINICAL_TRIALS trial_result · 2022-05-31Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Palmoplantar Pustulosis [Phase 2]
Phase 2 study evaluating the efficacy and safety of Imsidolimab (ANB019) in adults with palmoplantar pustulosis has completed, with results …
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CLINICAL_TRIALS trial_result · 2022-03-03Clinical Trial Update: A Study to Evaluate RIST4721 in Palmoplantar Pustulosis (PPP) [Phase 2]
Phase 2 study of RIST4721 in palmoplantar pustulosis has completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-01-06Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Japanese Subjects With Palmoplantar Pustulosis [Phase 2]
A Phase 2 trial evaluated the efficacy and safety of apremilast (CC-10004) in Japanese patients with palmoplantar pustulosis; the study comp…
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Apremilast in Patients With Moderate to Severe Palmoplantar Pustulosis (PPP) (APLANTUS) [Phase 2]
Phase 2 clinical trial update for apremilast in moderate to severe palmoplantar pustulosis (PPP) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-04-30Clinical Trial Update: Anakinra for Inflammatory Pustular Skin Diseases [Phase 2]
Phase 2 trial update on anakinra for inflammatory pustular skin diseases (Sneddon-Wilkinson, Acrodermatitis Continua of Hallopeau) with comp…
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: Initial Dosing of BI 655130 in Palmoplantar Pustulosis Patients [Phase 2]
Phase 2 trial update showing initial dosing of BI 655130 in patients with palmoplantar pustulosis (a form of psoriasis); results have been p…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: An Efficacy and Safety of Guselkumab in Participants With Palmoplantar Pustulosis [Phase 3]
Phase 3 trial results evaluating the efficacy and safety of guselkumab in palmoplantar pustulosis; the study is completed with results poste…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: A Study of the Efficacy, Safety and Tolerability of CNTO 1959, a Human Anti-IL 23 Monoclonal Antibody in Participants With Palmoplantar Pustulosis [Phase 2]
Phase 2 study of CNTO 1959 (guselkumab) in palmoplantar pustulosis completed to assess efficacy, safety and tolerability.
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CLINICAL_TRIALS trial_result · 2014-07-10Clinical Trial Update: Immune Signature of Palmoplantar Pustulosis
This clinical trial update notes the completion of a study assessing immune signatures in palmoplantar pustulosis.