Pain Management
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Sign up freeTop drugs studied for this disease
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FDA approval · 2026-08-14FDA Approved: BUPRENORPHINE AND NALOXONE — Supplemental Application (Camber Pharmaceuticals, Inc.)
Supplemental approval for a generic buprenorphine/naloxone product by Camber Pharmaceuticals, Inc. (ANDA 219850).
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CLINICAL_TRIALS trial_result · 2026-08-04Clinical Trial Results: Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Intensive Rehabilitation [Phase 2]
Phase 2 trial results on using conditioning and open-label placebo (COLP) to reduce opioid dose in intensive rehabilitation for spinal cord …
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CLINICAL_TRIALS trial_result · 2026-07-29Clinical Trial Results: The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain [Phase 4]
Phase 4 clinical trial comparing intravenous versus oral dexamethasone for postoperative nausea, vomiting, and pain; results completed and p…
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CLINICAL_TRIALS trial_result · 2026-07-22Clinical Trial Update: Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Liver Resection [Phase 3]
Phase 3 trial comparing patient-controlled epidural analgesia to intravenous patient-controlled analgesia for postoperative pain after elect…
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FDA approval · 2025-04-02FDA Approved: LIDOCAINE HYDROCHLORIDE — Original Application (Anthea Pharma Private Limited)
FDA approved a generic lidocaine hydrochloride product from Anthea Pharma Private Limited under an Original Application (ANDA 219535).
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Post-partum Non-pharmacologic Pain Management [NA]
A completed clinical trial evaluating post-partum non-pharmacologic pain management with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Regional Block for Postoperative Free Flap Care [Phase 4]
Phase 4 clinical trial assessing regional block for postoperative free flap pain management has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-07-25Clinical Trial Update: Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation [NA]
Clinical trial update reporting completion and posted results for a study evaluating transcutaneous electrical nerve stimulation (TENS) for …
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Comparison Between Bupivacaine and Bupivacaine With Dexmedetomidine in Caudal Block for Post Operative Pain Control [Phase 4]
Phase 4 trial comparing bupivacaine alone versus bupivacaine with dexmedetomidine for caudal block in postoperative pain control has complet…
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Pain Management in Pediatric Adenotonsillectomy [Phase 3]
A Phase 3 clinical trial update focusing on pain management in pediatric adenotonsillectomy is in progress, with current status not disclose…
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: Smartphone Technology to Alleviate Malignant Pain (STAMP) [NA]
A completed clinical trial evaluating smartphone technology (STAMP) for alleviating malignant pain in cancer patients; results posted in 202…
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CLINICAL_TRIALS trial_result · 2022-12-21Clinical Trial Update: Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia [Phase 3]
Phase 3 trial comparing intravenous subdissociative-dose ketamine to morphine for prehospital analgesia was terminated.
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CLINICAL_TRIALS withdrawal · 2022-11-03Clinical Trial Update: Articaine vs Lidocaine for Pediatric Dental Procedures [Phase 4]
Phase 4 trial comparing articaine to lidocaine for pediatric dental procedures has been withdrawn.
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CLINICAL_TRIALS trial_result · 2022-08-31Clinical Trial Update: Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery [Phase 4]
Phase 4 trial update evaluating regional anesthesia to reduce opioid use after functional endoscopic sinus surgery completed with results po…
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CLINICAL_TRIALS trial_result · 2022-07-19Clinical Trial Update: Suprainguinal Fascia Iliaca (SIFI) Block Improves Analgesia Following Total Hip Arthroplasty [Phase 4]
Phase 4 trial update on Suprainguinal Fascia Iliaca block showing analgesia improvement after Total Hip Arthroplasty (terminated with result…
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CLINICAL_TRIALS trial_result · 2022-07-18Clinical Trial Update: Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section [Phase 4]
Phase 4 trial update comparing EXPAREL to standard of care for pain management in elective cesarean section; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-06-10Clinical Trial Update: Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery [Phase 4]
Phase 4 clinical trial update evaluating a multi-modal anesthesia protocol for pain management in patients undergoing posterior lumbar spina…
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CLINICAL_TRIALS trial_result · 2022-05-26Clinical Trial Update: Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine [Phase 4]
Phase 4 trial updating post-cesarean analgesia using epidural morphine after epidural 2-chloroprocaine has completed with results posted in …
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CLINICAL_TRIALS trial_result · 2022-03-14Clinical Trial Update: Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet) [Phase 2]
Phase 2 trial comparing analgesic efficacy of MSIR/acetaminophen versus oxycodone/acetaminophen for pain management; trial completed with po…
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CLINICAL_TRIALS trial_result · 2022-02-23Clinical Trial Update: Efficacy of Local Anesthetic Through Continuous Infusion [Phase 3]
Phase 3 clinical trial evaluating the efficacy of a local anesthetic delivered through continuous infusion for pain control.
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease [Phase 3]
Phase 3 trial exploring hypnosis as a non-pharmacologic approach to manage pain and symptoms in sickle cell disease patients has completed.
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CLINICAL_TRIALS trial_result · 2021-08-03Clinical Trial Update: Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia [NA]
A completed clinical trial evaluated the combination of dexmedetomidine with low-dose nalmefene for preventing remifentanil-induced postoper…
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CLINICAL_TRIALS trial_result · 2021-06-01Clinical Trial Update: Dose-finding Study of Intrathecal Paracetamol Administered Immediately Before Spinal Anaesthesia [Phase 1, Phase 2]
Phase 1/2 dose-finding trial investigating intrathecal paracetamol administered before spinal anesthesia for pain management has completed w…
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CLINICAL_TRIALS trial_result · 2021-05-06Clinical Trial Update: MORphine Use in the Fascia Iliaca Compartment Block With UltraSound [Phase 4]
Phase 4 trial investigating morphine use in fascia iliaca compartment block with ultrasound for analgesia, currently terminated.
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CLINICAL_TRIALS trial_result · 2021-03-22Clinical Trial Update: EUS-Coeliac Plexus Block Versus Radiofrequency Ablation in Pain Relief of Patients With Malignancy [Phase 4]
A Phase 4 trial comparing EUS-Coeliac Plexus Block to radiofrequency ablation for pain relief in patients with pancreatic cancer/pancreatic …