Pain Acute
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Transauricular Vagal Nerve Stimulation, Pressure Pain and Interoception [NA]
A completed clinical trial evaluating transauricular vagal nerve stimulation for acute pain and its impact on pressure pain and interoceptio…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: The Effect of Heart Sound and White Noise on Pain and Physiological Parameters During Hepatitis B Vaccine Injection [NA]
A clinical trial evaluating whether heart sounds and white noise can reduce pain and alter physiological responses during Hepatitis B vaccin…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Intraoperative Methadone in Children Undergoing Surgery [Phase 3]
Phase 3 trial investigating intraoperative methadone in children undergoing surgery was terminated.
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CLINICAL_TRIALS trial_result · 2024-02-22Clinical Trial Update: Effect of High-dose Naloxone Following Third Molar Extraction [Phase 2]
Phase 2 clinical trial evaluating high-dose naloxone after third molar extraction; completed study with healthy subjects and hyperalgesia in…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKA [Phase 4]
Phase 4 clinical trial comparing femoral triangle block with popliteal plexus block, femoral triangle block, and adductor canal block for an…
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CLINICAL_TRIALS trial_result · 2023-08-29Clinical Trial Update: Lidocaine Intravenous in the Emergency Department For Sickle Cell Crisis [Phase 2]
Phase 2 trial investigating intravenous lidocaine for emergency department management of sickle cell crisis.
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty [Phase 4]
A Phase 4 clinical trial examined how combinations of paracetamol, ibuprofen, and dexamethasone affect patient-controlled morphine use in th…
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: Adjunct VR Pain Management in Acute Brain Injury [NA]
A completed clinical trial investigating adjunct VR pain management for acute brain injury, with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-02-28Clinical Trial Update: Prehospital Analgesia in Adults Using Inhaled Methoxyflurane : A Feasibility Study [Phase 4]
Phase 4 feasibility study on prehospital analgesia in adults using inhaled methoxyflurane for acute trauma pain.
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CLINICAL_TRIALS trial_result · 2023-02-23Clinical Trial Update: Liposomal Bupivacaine vs Peripheral Nerve Block [Phase 4]
A Phase 4 trial comparing liposomal bupivacaine to peripheral nerve block was terminated; results were posted in 2023. No detailed efficacy …
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CLINICAL_TRIALS trial_result · 2023-02-09Clinical Trial Update: Phase III Efficacy and Tolerability Trial of the Fixed Dose Combination of Etodolac 400 mg and Cyclobenzaprine 10 mg Versus Isolated Active Substances in Pain Control After Impacted Third Molar Extraction [Phase 3]
A Phase III trial evaluating a fixed-dose combination of etodolac and cyclobenzaprine versus individual components for pain control after im…
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CLINICAL_TRIALS trial_result · 2023-01-19Clinical Trial Update: Lidocaine Before Esophageal Manometry and Ambulatory pH Monitoring [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial evaluating lidocaine as a pre-procedure intervention for pain related to esophageal manometry and ambulator…
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CLINICAL_TRIALS trial_result · 2023-01-11Clinical Trial Update: Lornoxicam Versus Etodolac After Third Molar Surgery [Phase 4]
A Phase 4 clinical trial comparing lornoxicam to etodolac after third molar surgery has completed.
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CLINICAL_TRIALS trial_result · 2022-09-27Clinical Trial Update: Vibration Analgesia in Propofol Infusion During Anesthesia Induction [NA]
A completed clinical trial evaluating vibration analgesia during propofol infusion for anesthesia induction in acute pain conditions, with r…
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CLINICAL_TRIALS trial_result · 2022-09-13Clinical Trial Update: Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain [Phase 4]
Phase 4 clinical trial investigating ketamine with multilevel paravertebral block for postoperative pain after video-assisted thoracic surge…
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CLINICAL_TRIALS trial_result · 2022-06-30Clinical Trial Update: Eye Tracking as a Biomarker of Cannabis Effects [Phase 2]
Phase 2 trial investigating eye tracking as a biomarker of cannabis effects; the study was terminated with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-05-20Clinical Trial Update: Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment [Phase 4]
Phase 4 clinical trial evaluating the effect of paracetamol and ketorolac on RANK-L levels in patients starting orthodontic treatment.
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CLINICAL_TRIALS trial_result · 2022-05-02Clinical Trial Update: Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients [Phase 3]
Phase 3 clinical trial evaluating analgesic effects of cannabidiol for acute pain after simple tooth extractions.
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: Ibuprofen Plus Acetaminophen for Enhanced Pain Reduction [Phase 4]
A Phase 4 clinical trial updating on the use of ibuprofen plus acetaminophen for enhanced acute pain reduction is underway, with status curr…
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CLINICAL_TRIALS trial_result · 2022-03-25Clinical Trial Update: Ice Immersion Using Virtual Reality & Augmented Reality [NA]
A completed clinical trial investigating ice immersion using virtual reality and augmented reality for pain conditions, with results posted …
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CLINICAL_TRIALS trial_result · 2022-03-10Clinical Trial Update: Prospective Evaluation of Topical Analgesia for Laceration Repair in the Emergency Department [Phase 4]
Phase 4 trial evaluating topical analgesia for laceration repair in the emergency department has completed.
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CLINICAL_TRIALS trial_result · 2022-02-10Clinical Trial Update: Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children [Phase 3]
Phase 3 clinical trial comparing caudal block to dorsal penile nerve block plus ring block for postoperative pain management in infant and p…
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CLINICAL_TRIALS trial_result · 2021-11-09Clinical Trial Update: ESP in Breast Surgery Due to Cancer [Phase 4]
Phase 4 clinical trial update on ESP in breast surgery for breast cancer, focusing on pain management in an acute setting.
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: Tramadol Simultaneously With Sciatic Nerve Block for Calcaneus Fracture Osteosynthesis [Phase 4]
A Phase 4 clinical trial evaluated tramadol used with a sciatic nerve block for pain management after calcaneus fracture osteosynthesis; the…
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CLINICAL_TRIALS research · 2021-08-05Clinical Trial Update: Development and Validation of a Digital Pain-Reduction Kit for Musculoskeletal Injuries [NA]
A completed clinical trial investigating a digital pain-reduction kit for musculoskeletal injuries, with results posted in 2021.