Osteonecrosis of the Jaw
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Piezoeletric Surgery vs Conventional Surgery for Treatment of MRONJ [NA]
A clinical trial comparing piezoelectric surgery to conventional surgery for treating medication-related osteonecrosis of the jaw is not yet…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Medication Related Osteonecrosis of the Jaws (MRONJ) in a Cohort of Patients Treated by Antiresorptive Drugs
A ClinicalTrials.gov update indicates a study is recruiting to evaluate medication-related osteonecrosis of the jaw in patients treated with…
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CLINICAL_TRIALS other · 2024-05-17Clinical Trial Update: Leukocyte- and Platelet-Rich Fibrin in the Surgical Treatment of Medication-related Osteonecrosis of the Jaw [NA]
A clinical trial is evaluating leukocyte- and platelet-rich fibrin as a surgical adjunct in the treatment of medication-related osteonecrosi…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Impact of Topical Pentoxifylline and Tocopherol in Treatment and Prevention of Medically-related Osteonecrosis of the Jaws [NA]
A completed clinical trial evaluating topical pentoxifylline and tocopherol for treatment and prevention of osteonecrosis of the jaw related…
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CLINICAL_TRIALS trial_result · 2018-01-08Clinical Trial Update: Plasma Rich in Growth Factors for Treatment of Medication Related Osteonecrosis of the Jaw [Phase 2, Phase 3]
Clinical trial evaluating plasma rich in growth factors for osteonecrosis of the jaw associated with medications; current status is unknown …
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CLINICAL_TRIALS withdrawal · 2017-04-11Clinical Trial Update: Genetics in Predicting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid [NA]
A clinical trial evaluating genetic predictors of bisphosphonate-related osteonecrosis of the jaw in cancer patients treated with zoledronic…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Clinical Trial of Use of Autologous Bone Marrow Stem Cells Seeded on Porous Tricalcium Phosphate Matrix and Demineralized Bone Matrix in Patients With Osteonecrosis [Phase 1]
Phase 1 clinical trial update evaluating autologous bone marrow stem cells seeded on a porous tricalcium phosphate matrix and demineralized …
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EMA guidance · 2015-03-27Further measures to minimise risk of osteonecrosis of the jaw with bisphosphonate medicine
EMA announces enhanced risk-minimisation measures for osteonecrosis of the jaw associated with bisphosphonate medicines, including expanded …
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CLINICAL_TRIALS research · 2014-12-02Clinical Trial Update: Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer
A clinical trial update examining genetic risk factors for osteonecrosis of the jaw in patients with metastatic cancer, including those expo…
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: Bisphosphonate-Associated Jaw Osteonecrosis and PET Imaging
This completed clinical trial from the University of Arkansas studied bisphosphonate-associated osteonecrosis of the jaw and related jaw con…
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CLINICAL_TRIALS research · 2013-01-04Clinical Trial Update: Proposal For The Development Of A Well Defined Database For Patients With Oral Bisphosphonate-Related Osteonecrosis
This document outlines a proposal to develop a standardized database for patients with oral bisphosphonate-related osteonecrosis of the jaw.
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CLINICAL_TRIALS trial_result · 2011-06-16Clinical Trial Update: CONDOR Study of Osteonecrosis of the Jaws (TMJ)
A completed update on the CONDOR trial evaluating osteonecrosis of the jaw (jaw/TMJ region).
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CLINICAL_TRIALS trial_result · 2011-06-16Clinical Trial Update: DPBRN Retrospective Cohort Study of Osteonecrosis of the Jaw
This clinical trial update reports the completion of a retrospective cohort study conducted by the Dental Practice-Based Research Network on…
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CLINICAL_TRIALS trial_result · 2009-01-29Clinical Trial Update: The Influence of Bisphosphonates in the Oral Cavity in Children
This completed pediatric trial from Hadassah Medical Organization examined the effects of bisphosphonates on the oral cavity, including oste…