Osteonecrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2026-04-17Clinical Trial Update: The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head
The Cleveland Clinic-sponsored trial evaluating Genex for early-stage osteonecrosis of the femoral head is currently active but not recruiti…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Alendronate for Osteonecrosis in Adults With Sickle Cell Disease [Phase 2]
A Phase 2 clinical trial is evaluating alendronate for treating osteonecrosis in adults with sickle cell disease and is currently recruiting…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Phase II Trial of RAB001 (LLP2A-Alendronate) for Steroid-Induced Early-Stage Osteonecrosis of the Femoral Head [Phase 2]
This is a Phase II trial update for RAB001 (LLP2A-Alendronate) evaluating steroid-induced early-stage osteonecrosis of the femoral head; the…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Early Feasibility Study of Cartilage Defect Repair [NA]
Clinical trial update indicating that Cytex Therapeutics is recruiting for an early feasibility study of Cartilage Defect Repair addressing …
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Exactech Shoulder Post Market Clinical Follow-up Study
Exactech is conducting a post-market clinical follow-up study for shoulder implants, and participant recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Effect of HBOT on Femoral Head Avascular Necrosis (AVN) [NA]
Clinical trial update on evaluating hyperbaric oxygen therapy for femoral head osteonecrosis/avascular necrosis; status is not yet recruitin…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System
Clinical trial update indicating the Trabecular Metal Reverse Shoulder System outcomes study by Zimmer Biomet is active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis
A registry is being established to collect data on patients undergoing segmental mandibular defect reconstruction after oral squamous cell c…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Sickle Cell Disease (SCD) Bone Pain Study [NA]
Clinical trial update from UC Davis on sickle cell disease-related bone pain; the study is active but not recruiting, with results posted in…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: ACI-C Versus AMIC. A Randomized Trial Comparing Two Methods for Repair of Cartilage Defects in the Knee [NA]
A randomized trial comparing two knee cartilage repair methods (ACI-C vs AMIC) is active but not recruiting, with results posted on 2025-02-…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Imaging of Osteonecrosis With Ferumoxytol-Enhanced MRI [Phase 4]
This Phase 4 clinical trial investigated ferumoxytol-enhanced MRI for imaging osteonecrosis and has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Hypertension Intervention to Reduce Osteonecrosis in Children With Acute Lymphoblastic Leukemia/Lymphoma [Phase 2]
Phase 2 trial evaluating whether a hypertension intervention reduces osteonecrosis in children with acute lymphoblastic leukemia or lymphoma…
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CLINICAL_TRIALS trial_result · 2021-04-23Clinical Trial Update: Oxford Signature vs. Conventional Global Study [NA]
Clinical trial update for Oxford Signature versus conventional treatment in knee osteoarthritis; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: Post Market Clinical Follow-Up of the Zimmer Stafit Acetabular System
Post-market clinical follow-up study of the Zimmer Stafit Acetabular System has been terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: Avenir Müller Hip Stem Post Market Surveillance Study
Post-market surveillance study for the Avenir Müller Hip Stem completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Core Decompression With or Without Cement Packing for ONFH [Phase 1, Phase 2]
Phase 1/2 trial update on core decompression with or without cement packing for osteonecrosis shows completed status.
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CLINICAL_TRIALS trial_result · 2019-05-01Clinical Trial Update: A Short Metaphyseal Fitting Total Hip Arthroplasty in Young and Elderly Patients [Phase 4]
Phase 4 clinical trial update on a short metaphyseal fitting total hip arthroplasty in young and elderly patients; completed study.
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CLINICAL_TRIALS research · 2017-11-20Clinical Trial Update: Autologous Bone Marrow Stem Cell Transplantation for Osteonecrosis in Sickle Cell Disease [Phase 1, Phase 2]
This entry provides an update on a Phase 1/Phase 2 clinical trial evaluating autologous bone marrow stem cell transplantation for osteonecro…
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CLINICAL_TRIALS withdrawal · 2016-09-23Clinical Trial Update: Zoledronic Acid Treatment of Spontaneous Osteonecrosis of the Knee [Phase 2]
A Phase 2 trial of zoledronic acid for spontaneous osteonecrosis of the knee has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-08-04Clinical Trial Update: Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement [Phase 4]
A phase 4 multicenter study evaluating the long-term performance of the DePuy ASR hip system in resurfacing and primary total hip replacemen…
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CLINICAL_TRIALS research · 2015-10-06Clinical Trial Update: Direct Anterior Versus Posterior Total Hip Arthroplasty Surgical Approaches [NA]
A clinical trial comparing direct anterior versus posterior approaches for total hip arthroplasty is being conducted by New Lexington Clinic…
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CLINICAL_TRIALS research · 2015-01-07Clinical Trial Update: Osteoporosis and Knee Insufficiency Fracture
Clinical trial update concerning osteoporosis-related knee insufficiency fractures led by University of Sao Paulo General Hospital. The curr…
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CLINICAL_TRIALS research · 2014-11-18Clinical Trial Update: Talar Avascular Necrosis: Surgical Angiogenesis vs. Core Decompression [NA]
A clinical trial update comparing surgical angiogenesis versus core decompression for talar osteonecrosis (avascular necrosis).
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: Talar Avascular Necrosis: Surgical Angiogenesis vs. Core Decompression [NA]
This clinical trial compares surgical angiogenesis to core decompression for talar osteonecrosis, with the current status listed as UNKNOWN.
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Osteonecroses in Pediatric Patients With ALL
This clinical trial update describes observations of osteonecrosis in pediatric patients with acute lymphoblastic leukemia, associated with …