Osteoarthritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-07-14Clinical Trial Update: Comparison of Stability and Outcomes in Single-radius Femoral Component for Total Knee Arthroplasty
This clinical trial update compares the stability and outcomes of a single-radius femoral component used in total knee arthroplasty. The stu…
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CLINICAL_TRIALS trial_result · 2011-07-06Clinical Trial Update: Is There Increased Polyethylene Wear and Increased Periprosthetic Bone Loss in Femur in Reverse Hybrid Technique Compared With Conventional Cemented Technique in Total Hip Replacement? [NA]
The trial update reports completion of a clinical study comparing reverse hybrid cementless/cemented total hip replacement to conventional c…
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CLINICAL_TRIALS trial_result · 2011-06-29Clinical Trial Update: An Effectiveness and Safety Study of Two Doses of Acetaminophen Extended Release Caplets in the Treatment of Osteoarthritis of the Hip or Knee [Phase 3]
Phase 3 clinical trial update evaluating two dosing regimens of extended-release acetaminophen caplets for hip or knee osteoarthritis, focus…
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CLINICAL_TRIALS trial_result · 2011-06-17Clinical Trial Update: Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee [Phase 3]
A Phase 3 efficacy and safety trial of Naproxcinod for knee osteoarthritis has completed, with results providing an update on the drug's per…
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CLINICAL_TRIALS trial_result · 2011-06-17Clinical Trial Update: Analgesic Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee [Phase 3]
Phase 3 trial evaluating Naproxcinod for analgesic efficacy and safety in osteoarthritis of the knee has completed.
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CLINICAL_TRIALS trial_result · 2011-06-17Clinical Trial Update: To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension [Phase 1]
Phase 1 trial comparing naproxcinod to naproxen and ibuprofen to assess effects on arterial blood pressure in osteoarthritis patients with c…
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CLINICAL_TRIALS trial_result · 2011-06-17Clinical Trial Update: A Study to Assess the Effects of Naproxcinod and Naproxen on Blood Pressure Measurements in Osteoarthritis Patients With Controlled High Blood Pressure [Phase 1]
Phase 1 trial evaluating the blood pressure effects of Naproxcinod versus Naproxen in osteoarthritis patients with controlled hypertension.
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CLINICAL_TRIALS trial_result · 2011-06-17Clinical Trial Update: Double-Blind Follow-on Safety Study of HZT-501 (Ibuprofen 800 mg/Famotidine 26.6 mg) in Subjects Who Have Completed Participation in HZ-CA-301 (NCT00450658) or HZ-CA-303 (NCT00450216) [Phase 3]
A completed Phase 3 double-blind follow-on safety study of HZT-501 (ibuprofen 800 mg / famotidine 26.6 mg) in participants from prior trials…
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: A Study to Evaluate the Effectiveness and Safety of Multiple Doses of Tapentadol(CG5503) in Patients Awaiting Joint Replacement Surgery [Phase 3]
A Phase 3 study evaluating multiple doses of tapentadol (CG5503) in patients awaiting joint replacement surgery has completed, assessing eff…
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CLINICAL_TRIALS trial_result · 2011-06-14Clinical Trial Update: Effect of Glucosamine on Joint Structure and Quality of Life (JOG) [NA]
Completed clinical trial evaluating glucosamine's effect on joint structure and quality of life in people with osteoarthritis. Sponsor: Univ…
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FDA approval · 2011-06-13FDA Approved: NABUMETONE — Original Application (Actavis Pharma, Inc.)
FDA approves the original application for Nabumetone as a generic (ANDA) drug manufactured by Actavis Pharma, Inc.
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CLINICAL_TRIALS trial_result · 2011-06-09Clinical Trial Update: Safety and Efficacy of Autologous Bone Marrow Stem Cells for Treating Osteoarthritis [Phase 1, Phase 2]
The document describes a Phase 1/Phase 2 clinical trial evaluating the safety and efficacy of autologous bone marrow stem cells for treating…
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CLINICAL_TRIALS trial_result · 2011-06-09Clinical Trial Update: A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain [Phase 3]
A Phase 3 study evaluating 90-day safety of Tapentadol immediate-release versus Oxycodone immediate-release in adults with chronic pain, inc…
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CLINICAL_TRIALS research · 2011-06-09Clinical Trial Update: Arthroscopic Ankle Arthrodesis: Measuring Post-operative Pain to Assess the Potential for Outpatient Surgery.
This clinical trial update investigates arthroscopic ankle arthrodesis and measures postoperative pain to evaluate whether the procedure cou…
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CLINICAL_TRIALS trial_result · 2011-06-08Clinical Trial Update: Civamide in OA of the Knee(s) [Phase 3]
A Phase 3 trial evaluating civamide for knee osteoarthritis has completed. The sponsor is Winston Laboratories.
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CLINICAL_TRIALS trial_result · 2011-06-07Clinical Trial Update: Safety and Tolerability of PG110 in Patients With Knee Osteoarthritis Pain [Phase 1]
Phase 1 safety and tolerability study of PG110 in patients with knee osteoarthritis pain has been completed.
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CLINICAL_TRIALS trial_result · 2011-05-19Clinical Trial Update: Double-Blind,Randomized,Placebo-Controlled Efficacy & Safety Study of EUFLEXXA™ for Treatment of OA of the First CMC [Phase 2, Phase 3]
A double-blind, randomized, placebo-controlled study evaluating EUFLEXXA for osteoarthritis of the first carpometacarpal joint has completed…
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CLINICAL_TRIALS trial_result · 2011-05-18Clinical Trial Update: Efficacy and Safety of Tapentadol Extended Release Tablets in the Treatment of Moderate to Severe Pain in Subjects With Knee Osteoarthritis [Phase 2]
Phase 2 trial results evaluate the efficacy and safety of tapentadol extended-release tablets for moderate-to-severe pain in knee osteoarthr…
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, Compared With Placebo in Patients With Osteoarthritis [Phase 4]
A Phase 4 clinical trial comparing fentanyl transdermal patch to placebo in patients with osteoarthritis has completed.
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: Moxibustion for Knee Osteoarthritis [Phase 1, Phase 2]
The document notes completion of Phase 1 and Phase 2 clinical trials evaluating moxibustion for idiopathic osteoarthritis.
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CLINICAL_TRIALS trial_result · 2011-05-10Clinical Trial Update: Prescription Methods Assessment Project (PMAP) [NA]
The Prescription Methods Assessment Project (PMAP) clinical trial conducted by the American Academy of Family Physicians has been terminated…
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CLINICAL_TRIALS trial_result · 2011-05-09Clinical Trial Update: Effect of Cemented Stem Design on Periprosthetic Bone Mass Following Primary Total Hip Arthroplasty
This completed clinical trial evaluated whether cemented stem design in primary total hip arthroplasty influences periprosthetic bone mass.
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CLINICAL_TRIALS trial_result · 2011-04-29Clinical Trial Update: A 2 Week Blinded Study For Pain Due To Arthritis Of The Knee [Phase 2]
Pfizer-sponsored Phase 2 blinded trial for knee osteoarthritis was terminated; no results are provided in the available summary.
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CLINICAL_TRIALS trial_result · 2011-04-28Clinical Trial Update: Hydrotherapy Versus Physiotherapy for Short-term Rehabilitation After Primary TKR [NA]
Completed clinical trial comparing hydrotherapy to conventional physiotherapy for short-term rehabilitation after primary total knee replace…
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CLINICAL_TRIALS trial_result · 2011-04-27Clinical Trial Update: Predictive Genetic Risk Assessment Trial
This Mayo Clinic-sponsored trial on Predictive Genetic Risk Assessment has completed, investigating genetic risk prediction across multiple …