Osteoarthritis
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CLINICAL_TRIALS withdrawal · 2026-02-27Clinical Trial Update: Genicular Embolization Using Doxycycline Sclerotherapy [Phase 2]
The Phase 2 trial evaluating genicular embolization with doxycycline scleros therapy for chronic knee pain due to osteoarthritis has been wi…
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CLINICAL_TRIALS withdrawal · 2026-02-27Clinical Trial Update: Stromal Vascular Fraction (SVF) for Knee Post-Trauma Osteoarthritis (PTOA) [EARLY_Phase 1]
The EARLY Phase 1 trial evaluating Stromal Vascular Fraction for knee post-trauma osteoarthritis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: The Phosphodiesterase 3 Inhibitor Cilostazol as an Adjunct to Conventional Therapy in Patients With Osteoarthritis [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating cilostazol as an adjunct to conventional therapy for osteoarthritis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-01-22Clinical Trial Update: Surgical Weight-Loss to Improve Functional Status Trajectories Following Total Knee Arthroplasty (SWIFT Trial)
The SWIFT trial investigating surgical weight-loss to improve functional status after total knee arthroplasty has been terminated.
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CLINICAL_TRIALS withdrawal · 2024-12-24Clinical Trial Update: PMCF Study on the Safety, Performance and Clinical Benefits Data of the NexGen TM Augmentation Patella
The PMCF study evaluating the safety, performance and clinical benefits data of the NexGen TM Augmentation Patella has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-10-09Clinical Trial Update: The Clinical Impact of Diet on Medical Conditions Treated Within Bundled Payment Models: a Pilot Study [NA]
A pilot clinical trial evaluating the impact of diet on conditions treated under bundled payment models has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Validate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects [Phase 2]
Phase 2 trial evaluating oxytocin for peripheral analgesic effects in knee osteoarthritis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-02-06Clinical Trial Update: Investigating RELEARN Neurofeedback as Treatment for Chronic Musculoskeletal Pain [Phase 2, Phase 3]
A Phase 2/Phase 3 trial investigating RELEARN Neurofeedback for chronic musculoskeletal pain has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2022-10-27Clinical Trial Update: Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement [Phase 4]
A Phase 4 trial evaluating intraoperative injections for postoperative pain control during total hip replacement has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2022-02-18Clinical Trial Update: A Study of Etoricoxib in Participants With Osteoarthritis Not Responding to Analgesic Drugs (MK-0663-142) [Phase 4]
A Phase 4 clinical trial of etoricoxib in osteoarthritis participants not responding to analgesics was withdrawn.
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EMA withdrawal · 2022-02-15EMA Refused: Raylumis (tanezumab) — Pfizer Europe MA EEIG
The EMA refused the marketing authorization for Raylumis (tanezumab) from Pfizer Europe MA EEIG for osteoarthritis and pain, with a decision…
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CLINICAL_TRIALS withdrawal · 2020-01-23Clinical Trial Update: Liposomal Bupivacaine Versus Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Total Knee Arthroplasty [Phase 4]
Phase 4 trial comparing liposomal bupivacaine to standard bupivacaine with dexamethasone for knee surgery was withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-10-23Clinical Trial Update: Intraarticular Platelet-rich Plasma Injections Versus Corticosteroid Injections in Primary Knee Osteoarthritis [Phase 4]
A Phase 4 clinical trial comparing intraarticular platelet-rich plasma injections to corticosteroid injections for primary knee osteoarthrit…
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CLINICAL_TRIALS withdrawal · 2019-01-31Clinical Trial Update: Comparing X-3 To N2vac Polyethylene With the Triathlon Total Knee System [Phase 4]
A Phase 4 clinical trial comparing X-3 to N2vac polyethylene used with the Triathlon Total Knee System for osteoarthritis has been withdrawn…
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CLINICAL_TRIALS withdrawal · 2017-12-12Clinical Trial Update: "Blind" vs. Fluoroscopy-Guided Steroid Injections for Knee Osteoarthritis [NA]
A clinical trial comparing blind versus fluoroscopy-guided steroid injections for knee osteoarthritis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-08-10Clinical Trial Update: Safety and Feasibility Study of Autologous Stromal Vascular Fraction (SVF) Cells for Treatment of Osteoarthritis [Phase 1, Phase 2]
A clinical trial update indicates that the Phase 1/Phase 2 safety and feasibility study of autologous stromal vascular fraction (SVF) cells …
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CLINICAL_TRIALS withdrawal · 2017-07-07Clinical Trial Update: Retrospective Study on Cenos Stem With BoneMaster HA
A retrospective study of Cenos Stem with BoneMaster HA for osteoarthritis was withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-06-28Clinical Trial Update: A Multi-centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Polyethylene-on-metal Bearing in Primary Total Hip Replacement [Phase 4]
Phase 4 multi-centre study assessing the long-term performance of the Pinnacle hip cup with a polyethylene-on-metal bearing in primary total…
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CLINICAL_TRIALS withdrawal · 2017-06-21Clinical Trial Update: A Clinical Investigation of the Comprehensive®, BioModular®, and Bi-Angular® Shoulder Systems
A clinical trial update indicates the investigation of the Comprehensive®, BioModular®, and Bi-Angular® Shoulder Systems sponsored by Biomet…
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CLINICAL_TRIALS withdrawal · 2017-06-21Clinical Trial Update: Vanguard Knee Anterior Stabilized Versus Posterior Stabilized Bearing Study [NA]
A clinical trial comparing Vanguard knee anterior-stabilized versus posterior-stabilized bearing implants sponsored by Zimmer Biomet has bee…
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CLINICAL_TRIALS withdrawal · 2017-06-21Clinical Trial Update: Pro Osteon Bone Void Filler Study
A clinical trial of Pro Osteon Bone Void Filler sponsored by Zimmer Biomet has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-06-21Clinical Trial Update: A Clinical Investigation of Recovery Following Hip Resurfacing or Total Hip Arthroplasty [NA]
A clinical trial evaluating recovery after hip resurfacing or total hip arthroplasty has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-06-21Clinical Trial Update: Total Knee Replacement Using Simplex® or Cobalt™ Bone Cement
A clinical trial comparing Simplex and Cobalt bone cements for total knee replacement has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-06-19Clinical Trial Update: Clinical Evaluation on HA Coated Dynamic Hip Screws for Trochanteric Femoral Fractures [NA]
A Zimmer Biomet trial evaluating HA-coated Dynamic Hip Screws for trochanteric femoral fractures has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-04-19Clinical Trial Update: Treatment of Chronic Pain From Osteoarthritis [Phase 4]
A Phase 4 clinical trial investigating treatment for chronic pain associated with osteoarthritis has been withdrawn.