Osteoarthritis of the Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-03-25Clinical Trial Update: The Use of Fibrin Sealant to Reduce Bleeding After Total Knee Replacement [NA]
A completed clinical trial evaluated whether fibrin sealant can reduce bleeding after total knee replacement.
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CLINICAL_TRIALS trial_result · 2013-03-14Clinical Trial Update: Efficacy Study of Neridronate to Treat Painful Osteoarthritis of the Knee With Bone Marrow Lesions. [Phase 2]
A Phase 2 clinical trial evaluating neridronate for pain in knee osteoarthritis with bone marrow lesions; the current status is unknown.
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CLINICAL_TRIALS trial_result · 2013-03-06Clinical Trial Update: Gait Retraining to Reduce Knee Osteoarthritis Pain [Phase 1, Phase 2]
Update on a gait retraining intervention for knee osteoarthritis, studied in a combined Phase 1/Phase 2 trial and now completed.
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CLINICAL_TRIALS trial_result · 2013-03-06Clinical Trial Update: Early Ambulation After Adductor Canal Block for Total Knee Arthroplasty [NA]
The study evaluating early ambulation after adductor canal block for total knee arthroplasty was terminated.
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CLINICAL_TRIALS trial_result · 2013-02-22Clinical Trial Update: Accuracy of MRI-based Patients Matched Instruments vs Jig-based Instruments in Total Knee Arthroplasty (TKA) [NA]
This completed clinical trial update evaluates the accuracy of MRI-based, patient-matched instruments versus traditional jig-based instrumen…
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CLINICAL_TRIALS trial_result · 2013-02-15Clinical Trial Update: Scorpio® Cruciate Retaining (CR) Outcomes Study [NA]
The Scorpio Cruciate Retaining knee replacement outcomes study was terminated, with results posted in February 2013.
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CLINICAL_TRIALS withdrawal · 2013-02-07Clinical Trial Update: The Effectiveness of Antibiotic Cement (ABC) Compared to Regular Cement in Reducing the Rate of Infection Following Total Knee Arthroplasty: The ABC Trial [Phase 3]
A Phase 3 trial comparing antibiotic cement to regular cement to reduce infection after total knee arthroplasty has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: Cost-Effectiveness of Web-Based Follow Ups [NA]
Completed clinical trial evaluating the cost-effectiveness of web-based follow-ups for patients with knee or hip osteoarthritis.
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CLINICAL_TRIALS trial_result · 2013-01-25Clinical Trial Update: Periarticular Multimodal Drug Injections in Total Knee Arthroplasty [Phase 4]
Phase 4 clinical trial evaluating periarticular multimodal drug injections in total knee arthroplasty; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Efficacy of Spearmint Tea in Relieving Osteoarthritis of the Knee [Phase 4]
Phase 4 clinical trial update showing efficacy of spearmint tea in relieving symptoms of osteoarthritis of the knee.
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: Knee Arthroplasty Performed With Conventional and Customized Instrumentation [Phase 4]
A Phase 4 clinical trial evaluating conventional versus customized instrumentation in knee arthroplasty has completed, with results posted i…
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee [Phase 2]
Phase 2 trial of ABT-652 in adults with osteoarthritis of the knee has completed, with no results detailed in the update.
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CLINICAL_TRIALS research · 2012-12-13Clinical Trial Update: Shared Decision Making in Patients With Osteoarthritis of the Hip and Knee [NA]
This clinical trial update reports a completed study from the University of California, San Francisco on shared decision making in patients …
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CLINICAL_TRIALS trial_result · 2012-12-12Clinical Trial Update: A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee [Phase 1]
A Phase 1 safety and tolerability study of PF-05089771 in healthy subjects and in individuals with osteoarthritis of the knee has completed.
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CLINICAL_TRIALS trial_result · 2012-11-21Clinical Trial Update: The Efficacy and Safety of Intraarticular Sodium Hyaluronate (Hyalgan) After Proximal Tibial Osteotomy in Treatment of Knee Osteoarthritis Patients [Phase 2]
Phase 2 clinical trial evaluating efficacy and safety of intraarticular Hyalgan (sodium hyaluronate) after proximal tibial osteotomy in knee…
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CLINICAL_TRIALS trial_result · 2012-11-21Clinical Trial Update: Study of Evaluating the Duration of Efficacy of One Intra Articular Injection of Sodium Hyaluronate 2.0% in Patients With Painful Osteoarthritis of the Knee [Phase 2]
This document reports on a Phase 2 clinical trial evaluating the duration of efficacy of a single intra-articular injection of 2.0% sodium h…
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CLINICAL_TRIALS trial_result · 2012-11-07Clinical Trial Update: Is Botox Effective in Relieving Pain From Knee Osteoarthritis? [Phase 1]
A Phase 1 trial sponsored by Mayo Clinic evaluated whether Botox (onabotulinumtoxinA) can relieve pain in knee osteoarthritis; the study sta…
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CLINICAL_TRIALS trial_result · 2012-10-23Clinical Trial Update: Cupping in Osteoarthritis of the Knee [NA]
This clinical trial update notes that the study evaluating cupping for osteoarthritis of the knee has completed.
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CLINICAL_TRIALS trial_result · 2012-10-05Clinical Trial Update: A Study Comparing Duloxetine Versus Placebo in Patients Taking a Nonsteroidal Anti-inflammatory Drug (NSAID) for Knee Pain Due to Osteoarthritis [Phase 3]
Phase 3 study comparing duloxetine to placebo in knee osteoarthritis patients using NSAIDs; the trial is completed and results were posted i…
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CLINICAL_TRIALS trial_result · 2012-08-27Clinical Trial Update: A Study Comparing the Effectiveness and Safety of Varying Dose Strengths (100, 200, 300 and 400 mg) of Extended-release Tramadol HCl With Placebo for the Treatment of Osteoarthritis(OA) of the Knee and/or Hip [Phase 3]
It summarizes a completed Phase 3 trial comparing multiple doses of extended-release tramadol hydrochloride with placebo for osteoarthritis …
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CLINICAL_TRIALS research · 2012-07-23Clinical Trial Update: Preoperative Strength Training in Patients With Total Knee Arthroplasty [NA]
ClinicalTrials.gov entry for a study evaluating preoperative strength training in patients undergoing total knee arthroplasty; current statu…
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: Evaluation of Clinical Endpoints of Two Diclofenac Sodium Gel 1% [Phase 3]
Phase 3 trial evaluating clinical endpoints for two diclofenac sodium 1% gel formulations in osteoarthritis of the knee. The study has compl…
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CLINICAL_TRIALS trial_result · 2012-07-10Clinical Trial Update: Impact of Noninvasive Targeted Pulsed Electromagnetic Field (tPEMF) on Opioid Use, Pain, and Joint Function Following Total Knee Arthroplasty [Phase 4]
Phase 4 trial evaluating noninvasive targeted pulsed electromagnetic field (tPEMF) to reduce opioid use and improve pain and knee function a…
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CLINICAL_TRIALS trial_result · 2012-06-29Clinical Trial Update: Outcome of Patients After Total Knee Replacement: A Comparison of Femoral Nerve Block and Epidural Anesthesia [NA]
Completed clinical trial comparing femoral nerve block versus epidural anesthesia for total knee replacement, reporting patient outcomes inc…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: Investigation of Specific Protein/Markers in Patients With Osteoarthritis of the Knee Having a Total Knee Replacement
A completed AstraZeneca-sponsored clinical trial investigated specific proteins/markers in patients with osteoarthritis of the knee undergoi…