Osteoarthritis of the Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-11-04Clinical Trial Update: Improving Motivation for Physical Activity in Arthritis Clinical Trial [NA]
A Northwestern University clinical trial aimed at improving motivation for physical activity in people with knee osteoarthritis and rheumato…
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CLINICAL_TRIALS trial_result · 2013-10-30Clinical Trial Update: Supporting Decision Making for Musculoskeletal Preference-Sensitive Care [NA]
This clinical trial update notes the completion and posting of results for a study aimed at supporting decision making in musculoskeletal ca…
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CLINICAL_TRIALS trial_result · 2013-10-23Clinical Trial Update: Descriptive Study of Strength Training Exercises to Activate the Muscles of the Operated Leg After Total Knee Replacement [Phase 1]
A Phase 1 descriptive trial conducted at Copenhagen University Hospital Hvidovre evaluating strength training to activate the muscles of the…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: Outcome EnduRo Versus LINK SL Rotating Hinge Knee
Clinical trial update comparing EnduRo versus LINK SL Rotating Hinge Knee for knee osteoarthritis; the trial status is currently unknown.
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CLINICAL_TRIALS trial_result · 2013-09-11Clinical Trial Update: The Difference Between Rehabilitation With or Without Strength Training After Total Knee Replacement [Phase 2]
A phase 2 study comparing rehabilitation with strength training versus rehabilitation without strength training after total knee replacement…
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CLINICAL_TRIALS trial_result · 2013-09-06Clinical Trial Update: The Importance of Different Implant Surfaces of the Tibial Component for Migration and Adaptive Bone Remodeling in Uncemented Total Knee Arthroplasty (Vanguard Versus Regenerex) [Phase 4]
A Phase 4 clinical trial comparing Vanguard and Regenerex tibial implant surfaces in uncemented total knee arthroplasty evaluated migration …
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CLINICAL_TRIALS research · 2013-09-05Clinical Trial Update: Blood Levels of Local Anaesthetic in Knee Arthroplasty Using a Continuous Infusion Device
This clinical trial update investigates blood levels of a local anaesthetic delivered by a continuous infusion device in knee replacement su…
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CLINICAL_TRIALS trial_result · 2013-08-29Clinical Trial Update: Intrathecal Diamorphine Versus Femoral Nerve Block in Primary Total Knee Arthroplasty [NA]
This completed clinical trial compares intrathecal diamorphine with a femoral nerve block for pain management in primary total knee arthropl…
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CLINICAL_TRIALS trial_result · 2013-08-22Clinical Trial Update: The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee Arthroplasty [Phase 4]
Phase 4 clinical trial evaluating adductor canal blockade for reducing pain and opioid use after revision knee arthroplasty; the study has c…
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CLINICAL_TRIALS trial_result · 2013-07-08Clinical Trial Update: A Study to Evaluate the Effectiveness and Safety of Slow Release Hydromorphone HCL for Treatment of Patients With Osteoarthritis [Phase 3]
A Phase 3 clinical trial evaluating slow-release hydromorphone hydrochloride for osteoarthritis of the hip and knee has completed.
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CLINICAL_TRIALS trial_result · 2013-07-03Clinical Trial Update: Efficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee Pain [Phase 4]
A Phase 4 study reported results on the efficacy and safety of the fentanyl transdermal patch in adults with knee osteoarthritis.
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: Experimental Study of Strength Training to Activate the Quadriceps Muscle After Total Knee Arthroplasty [NA]
A completed clinical trial evaluating a quadriceps-strengthening intervention to activate the quadriceps after total knee arthroplasty in kn…
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CLINICAL_TRIALS trial_result · 2013-06-19Clinical Trial Update: Teriparatide for Improved Knee Prosthesis Fixation [Phase 2]
A Phase 2 clinical trial evaluating teriparatide for improving fixation of knee prostheses in osteoarthritis of the knee has completed. The …
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CLINICAL_TRIALS trial_result · 2013-06-11Clinical Trial Update: Blood Levels of Local Anaesthetic in Knee Arthroplasty
This completed clinical trial measured blood levels of a local anaesthetic used during knee arthroplasty. The trial was sponsored by Golden …
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CLINICAL_TRIALS research · 2013-06-11Clinical Trial Update: 'M'-Technique, Guided Imagery, or Standard of Care on Anxiety and Pain Pre- & Post-operatively in Elective Joint Replacement Patients [NA]
This clinical trial investigates whether the M-Technique, guided imagery, or standard care affects anxiety and pain before and after electiv…
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CLINICAL_TRIALS trial_result · 2013-06-10Clinical Trial Update: Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Affected Knee Osteoarthritis by Rheumatoid Arthritis [Phase 2, Phase 3]
A completed Phase 2 and Phase 3 trial evaluating transplantation of bone marrow–derived mesenchymal stem cells for knee osteoarthritis assoc…
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CLINICAL_TRIALS trial_result · 2013-05-31Clinical Trial Update: Clinical Efficacy Study Comparing VisionScope Imaging (VSI) to Magnetic Resonance Imaging (MRI) in Injuries of the Knee [NA]
A completed clinical efficacy study compared VisionScope Imaging (VSI) to MRI for knee injuries, including meniscal tears, loose bodies, and…
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CLINICAL_TRIALS trial_result · 2013-05-21Clinical Trial Update: A Study Of The Safety And Efficacy Of PF-04191834 In Patients With Osteoarthritis Of The Knee [Phase 2]
A Phase 2 study of PF-04191834 for osteoarthritis of the knee was terminated, and results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-05-21Clinical Trial Update: Efficacy and Safety of Single, Low-dose Dexamethasone in Patients After Total Knee Arthroplasty [Phase 4]
Phase 4 trial assessing the efficacy and safety of a single low-dose dexamethasone given after total knee arthroplasty in patients with knee…
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CLINICAL_TRIALS trial_result · 2013-05-17Clinical Trial Update: Aerobic Exercise Intervention for Knee Osteoarthritis [NA]
This update notes the completion of a Mayo Clinic-sponsored clinical trial evaluating aerobic exercise as an intervention for knee osteoarth…
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CLINICAL_TRIALS trial_result · 2013-05-15Clinical Trial Update: A Study of ABT-652 in Combination With a Nonsteroidal Anti-Inflammatory Drug (NSAID) in Adults With Osteoarthritis Pain of the Knee [Phase 2]
A Phase 2 study evaluating ABT-652 in combination with a nonsteroidal anti-inflammatory drug for knee osteoarthritis pain has completed.
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Preoperative Alignment of Total Knee Replacement [Phase 3]
Phase 3 clinical trial update on preoperative alignment for total knee replacement; results have been posted.
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Assays for and Reversal of New Anticoagulants
Clinical trial update describing assays and reversal approaches for newer anticoagulants, with relevance to patients with atrial fibrillatio…
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CLINICAL_TRIALS withdrawal · 2013-05-01Clinical Trial Update: DePuy Revision TKA Implant 5yr Survivorship
The clinical trial evaluating the five-year survivorship of the DePuy revision total knee arthroplasty implant has been withdrawn. No furthe…
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CLINICAL_TRIALS trial_result · 2013-04-23Clinical Trial Update: Echogenic Versus Stimulating Needle and Catheter for Sciatic Blocks [Phase 3]
This entry reports the completion of a Phase 3 trial comparing echogenic versus stimulating needles and catheters for sciatic nerve blocks, …