Osteoarthritis of the Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS) [NA]
An upcoming clinical trial sponsored by Pamukkale University compares platelet-rich plasma injections with activated cytokine-rich serum inj…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Comparison of a Single RTX-GRT7039 and Placebo Intra-articular Injection for Pain Associated With Osteoarthritis of the Knee [Phase 3]
A Phase 3 trial comparing a single RTX-GRT7039 intra-articular injection to placebo in knee osteoarthritis has completed and posted results.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization [NA]
SakuraBead is being studied as a resorbable embolic agent for genicular artery embolization in knee osteoarthritis; the trial is currently a…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Evaluation of Muscle Oxygenation and Recovery Dynamics in Individuals With Knee Osteoarthritis
A clinical trial update shows ongoing recruitment for a study measuring muscle oxygenation and recovery dynamics in individuals with knee os…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Counterpain PXM Versus Diclofenac Versus Piroxicam [Phase 3]
Phase 3 trial comparing Counterpain PXM versus Diclofenac and Piroxicam for ankle sprain, back pain, knee osteoarthritis, tennis elbow, and …
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Muscle Recovery After Total Knee Arthroplasty
Clinical trial update reporting results on muscle recovery after total knee arthroplasty in knee osteoarthritis patients.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR) [Phase 1, Phase 2]
A Phase 1/2 clinical trial is currently recruiting to evaluate recombinant human growth hormone for knee osteoarthritis (KORR).
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Metformin Safety and Efficacy in Osteoarthritis. [Phase 3]
A Phase 3 clinical trial is evaluating the safety and efficacy of metformin in knee osteoarthritis and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Feasibility of Choose to Move Replacement Ready [NA]
A University of British Columbia feasibility study is evaluating the Choose to Move Replacement Ready program and is currently recruiting. T…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Knee Injections for Obese Patients With Knee Arthritis [Phase 4]
This clinical trial update describes a Phase 4 study evaluating knee injections for obese patients with knee osteoarthritis, currently recru…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: A Phase 1/2a Study to Evaluate Single Intraarticular Injections of 3 Dose Levels of SYN321 and Placebo in Patients With Symptomatic Knee Osteoarthritis [Phase 1, Phase 2]
A completed Phase 1/2a study evaluated three intraarticular dose levels of SYN321 versus placebo for symptomatic knee osteoarthritis.
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CLINICAL_TRIALS other · 2026-03-06Clinical Trial Update: Low Frequency Ultrasound for Osteoarthritis Healing and Rehabilitation [NA]
Clinical trial NCT06562374 sponsored by The University of Texas Medical Branch evaluating low-frequency ultrasound for osteoarthritis of the…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Multimodal Treatment of Knee Osteoarthritis: Therapeutic Exercise and Noninvasive Neuromodulation (NESA) Versus Therapeutic Exercise and Transcutaneous Electrical Nerve Stimulation (TENS) in People Over 60 Years of Age. [NA]
Clinical trial comparing two noninvasive treatment approaches for knee osteoarthritis in adults over 60: therapeutic exercise with noninvasi…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Measurement of Osteoarthritic Patient Pain Through Electrodermal Activity Signals [NA]
A clinical trial is exploring whether electrodermal activity signals can quantify pain in knee osteoarthritis, currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: A Trial of Intraoperative Fibrin Sealant on Postoperative Recovery After Total Knee Replacement [Phase 4]
A Phase 4 clinical trial evaluating intraoperative fibrin sealant for improving postoperative recovery after total knee replacement has been…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Results Between Robotic-assisted and Manual Total Knee Arthroplasty With Kinematic Alignment [NA]
This clinical trial update compares robotic-assisted total knee arthroplasty with manual total knee arthroplasty using kinematic alignment.
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Peripheral Nerve Blocks and Postoperative Pain and Mobilization After Total Knee Arthroplasty
Clinical trial evaluating peripheral nerve blocks to improve postoperative pain control and mobilization after total knee arthroplasty has c…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Persona IQ Cohort Study
The document reports that a Zimmer Biomet study, the Persona IQ Cohort Study, is currently enrolling by invitation to evaluate the Persona I…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Personalized Digital Training Intervention to Reduce Inflammation by Correcting Pathological Movement Patterns in Pre-stage Knee Osteoarthritis After Anterior Cruciate Ligament Reconstruction [NA]
A clinical trial is investigating a personalized digital training program designed to reduce knee inflammation by correcting pathological mo…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Evaluation of Outcomes of the Triathlon Hinge Knee (THK) System
An ongoing clinical trial sponsored by The Cleveland Clinic is recruiting to evaluate outcomes of the Triathlon Hinge Knee System for knee j…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Wound Closure Materials and Techniques in Hip and Knee Arthroplasty [NA]
Clinical trial registry entry for a study comparing wound closure materials and techniques in hip and knee arthroplasty. The study is curren…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Safety and Performance of the Journey™ II UNI Unicompartmental Knee System
Completed clinical trial NCT03768128 evaluating the safety and performance of the Journey II UNI Unicompartmental Knee System in knee degene…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Clinical Performance and Safety of the Unicompartmental Univation® XF Pro Implant
This clinical trial entry describes planned evaluation of the Ununicompartmental Univation XF Pro knee implant's performance and safety in g…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA [Phase 4]
Phase 4 clinical trial update noting a study comparing Zynrelef liposomal bupivacaine to periarticular injections for post-operative pain re…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Muscle Fatigability and Trip-specific Fall Risk in Adults With Knee Osteoarthritis [NA]
This clinical trial update reports on a completed study examining muscle fatigability and trip-related fall risk in adults with knee osteoar…