Osteoarthritis of the Knee
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: 3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Knee Osteoarthritis [Phase 3]
A 3-year Phase 3 open-label trial evaluating Lorecivivint for knee osteoarthritis was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty [Phase 4]
A Phase 4 trial comparing dexamethasone versus dexmedetomidine as adjuvants to an erector spinae plane block for pain management after knee …
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: pAF for the Treatment of Osteoarthritis [Phase 1, Phase 2]
Clinical trial update for pAF in osteoarthritis of the knee. Phase 1 and Phase 2 studies have been completed, with results posted on 2026-03…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Technology Interventions to Improve Outcomes After Knee Replacement [NA]
A completed clinical trial evaluated technology-based interventions to improve outcomes after knee replacement, and results have been posted…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: The Energize! Study for Adults With Knee Replacement [NA]
The Energize! Study for adults undergoing knee replacement has completed and posted its results. The trial was sponsored by the University o…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Impact of a Technique of Massage During the First Week of Hospitalization on the Recycling of the Mobility of the Knee Further to the Installation of Knee Replacement [NA]
The study evaluated a massage technique during the first week after knee replacement to improve knee mobility. The trial has completed.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty
A clinical trial comparing navigation-assisted OrthoPilot Elite with robotic-assisted MAKO for total knee arthroplasty, currently recruiting…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success [NA]
IMAGES is a trial investigating whether metabolic imaging can identify signals that predict success of genicular artery embolization in knee…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Image Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis [NA]
A clinical trial is evaluating image-guided genicular nerve radiofrequency ablation for osteoarthritis of the knee, with recruitment not yet…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: The Effectiveness of BETY in Knee Osteoarthritis With Intra-Articular Injections [NA]
A clinical trial update indicates that a study evaluating BETY for knee osteoarthritis with intra-articular injections is currently recruiti…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Extended Oral Tranexamic Acid After Primary Total Knee Arthroplasty [NA]
This clinical trial update notes a study evaluating extended oral tranexamic acid after primary total knee arthroplasty, currently not yet r…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain [Phase 3]
A Phase III study evaluating SL1002 for osteoarthritis of the knee is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Native Alignment in the Setting of an Arthritic Knee in Total Knee Arthroplasty [NA]
The clinical trial evaluating native alignment in total knee arthroplasty for osteoarthritis of the knee has been terminated.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy [NA]
This clinical trial compares rehabilitation after total knee arthroplasty using a smart orthotic versus standard outpatient physical therapy…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Effectiveness of Stanley Paris Manual Therapy vs. Conventional Physiotherapy in Reducing Pain and Improving Function in Grade II Knee Osteoarthritis [NA]
A completed clinical trial comparing Stanley Paris Manual Therapy to conventional physiotherapy for grade II knee osteoarthritis. The study …
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: A Long-Term Safety and Efficacy Study of Lorecivivint in Subjects With Osteoarthritis of the Knee [Phase 3]
Phase 3 long-term safety and efficacy study of lorecivivint in osteoarthritis of the knee has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Pilot Study to Identify and Validate Digital Biomarkers in Osteoarthritis of the Knee [NA]
A completed pilot clinical trial aimed at identifying and validating digital biomarkers for osteoarthritis of the knee.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Cross-Education From Unilateral Strength and Balance Training in Older Adults With Bilateral Knee Osteoarthritis [NA]
This entry updates a clinical trial investigating cross-education from unilateral strength and balance training in older adults with bilater…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis [NA]
This ClinicalTrials.gov entry (NCT06940479) from the University of Colorado, Denver, studies changes in synovial fluid before and after GAE …
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CLINICAL_TRIALS other · 2026-03-24Clinical Trial Update: A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee [Phase 2]
Phase 2 trial update for PCRX-201 assessing safety and tolerability in osteoarthritis of the knee; currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform [NA]
This entry reports the completion of a prospective multicenter longitudinal cohort study evaluating Zimmer Biomet's Mymobility Platform for …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Corticosteroid Meniscectomy Randomized Trial [Phase 4]
Phase 4 randomized trial evaluating the use of corticosteroids in patients undergoing meniscectomy for knee conditions.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Platelet Rich Plasma for Musculoskeletal Conditions [NA]
A University of Utah-sponsored clinical trial is recruiting to evaluate platelet-rich plasma for several osteoarthritis indications and rela…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Effects of Including Interferential Current in a Therapeutic Exercise Program in Individuals With Knee Osteoarthritis [NA]
This clinical trial update notes a study evaluating whether adding interferential current to a therapeutic exercise program benefits individ…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA [NA]
A completed clinical trial evaluating periarticular multimodal drug injection for pain management after primary unilateral total knee arthro…