Osteoarthritis of Knee
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty [Phase 2]
Phase 2 clinical trial evaluating cannabidiol to reduce postoperative opioid use after primary total knee arthroplasty. The study is current…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal Block Combined With IPACK Block in Total Knee Arthroplasty [NA]
An ongoing clinical trial is evaluating liposomal bupivacaine versus ropivacaine, combined with either perineural dexamethasone or dexmedeto…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Effect of Combined Adductor Canal and AFCN Block on Postoperative Inflammation
A clinical trial evaluating whether combining adductor canal and AFCN nerve blocks reduces postoperative inflammation after total knee arthr…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Intra-Articular Catheter Total Knee Arthroplasty [Phase 4]
Phase 4 trial update on an intra-articular catheter method for continuous local infiltration analgesia in total knee arthroplasty; enrollmen…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Functional Impact at 12 Months Post-op of Posterior Cruciate Ligament Conservation During Robotic-assisted Surgery (MAKO) for Total Knee Replacement. [NA]
This clinical trial assesses functional outcomes 12 months after posterior cruciate ligament-conserving, robotic-assisted total knee replace…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Surgeon Physiologic Stress During Unicompartmental Knee Arthroplasty: Manual vs Computer-Assisted Technique
A clinical trial comparing manual versus computer-assisted techniques for unicompartmental knee arthroplasty, focusing on surgeon physiologi…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA) Procedure [NA]
Clinical trial evaluating the safety and effectiveness of the REAL INTELLIGENCE CORI system in total knee arthroplasty is currently recruiti…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Determinants for Return to Work After Primary Knee Arthroplasty [NA]
A clinical trial exploring determinants of returning to work after primary knee arthroplasty (knee replacement) is currently active but not …
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty [Phase 4]
Phase 4 clinical trial investigating how the route of dexamethasone affects pain and inflammation in iPACK with adductor canal block for kne…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Minimal Sedation During Knee Replacement Surgery [NA]
An ongoing Mayo Clinic trial is evaluating minimal sedation during knee replacement surgery (Total Knee Arthroplasty) and is currently recru…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Using a Smart Implantable Device to Compare Early Recovery in Two Different Knee Arthroplasty Approaches [NA]
A clinical trial evaluating a smart implantable device to compare early recovery between two knee arthroplasty approaches; recruitment has n…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Adductor Canal Block and IPACK Block vs Adductor Canal Block and the Gastrosoleus Interfascial Block After Total Knee Arthroplasty [NA]
This clinical trials registry entry describes a study comparing two anesthesia block strategies after total knee arthroplasty (adductor cana…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia [Phase 4]
A Phase 4 clinical trial comparing hyperbaric bupivacaine versus hyperbaric prilocaine for spinal anesthesia in total knee arthroplasty is c…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine [Phase 3]
A Phase 3 clinical trial evaluating whether intrathecal morphine reduces postoperative urinary retention in patients undergoing revision kne…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Cemented vs Cementless Persona Keel RCT [NA]
Clinical trial update showing an active but not recruiting randomized study comparing cemented versus cementless Persona Keel knee prosthese…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Clinical Utility and Gait Analysis of NextAR System AUS
This clinical trial update notes ongoing recruitment for evaluating the clinical utility and gait analysis of the NextAR System in patients …
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: The Effect of TENS on Early Patient Outcomes After Total Knee Arthroplasty [NA]
A clinical trial update indicates a study assessing the effect of transcutaneous electrical nerve stimulation (TENS) on early outcomes after…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Coupling of IPACK Block With Adductor Canal Block Versus Adductor Canal Block Alone on Pain, Functional Recovery and Inflammatory Response After Knee Replacement [NA]
This clinical trial will compare IPACK block plus adductor canal block to adductor canal block alone for knee replacement, assessing pain, f…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Combined Cyclic Compression Cryotherapy and Phased Rehabilitation Training for Recovery After Knee Replacement [NA]
This clinical trial update describes a study evaluating the combination of cyclic compression cryotherapy and phased rehabilitation training…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: The Effect of Benson's Relaxation Exercise on Anxiety and Kinesiophobia in Patients With Total Knee Arthroplasty [NA]
This clinical trial update reports on evaluating Benson's Relaxation Exercise for reducing anxiety and kinesiophobia in patients undergoing …
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Effect of Different Cold Therapy Programs in Patients Received Total Knee Arthroplasty Operation [NA]
This ongoing clinical trial is evaluating different cold therapy programs in patients who have undergone total knee arthroplasty.
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Efficacy of Microparticle Geniculate Artery Embolization in Total Knee Prosthesis Patients With Pain Resistant to Medical Treatment. A Prospective Randomized Controlled Trial [NA]
A prospective randomized controlled trial is evaluating whether microparticle embolization of the geniculate arteries can reduce chronic kne…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Patient Outcomes With Robotic-Assisted Total Knee Arthroplasty [NA]
A clinical trial update indicating enrollment by invitation for evaluating patient outcomes after robotic-assisted total knee arthroplasty.
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty [Phase 2]
A Phase 2 clinical trial is evaluating perioperative vitamin C to reduce persistent pain after total knee arthroplasty. The study is current…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Evaluation of Ioband Coverage Waterproof Dressing Versus Isolated Waterproof Dressing After Primary Total Knee Arthroplasty [NA]
This clinical trial update reports a study evaluating two waterproof dressings (Ioband Coverage Waterproof Dressing vs. isolated waterproof …